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ONC

BeOne Medicines Ltd

244 hedge funds and large institutions have $8.34B invested in BeOne Medicines Ltd in 2025 Q2 according to their latest regulatory filings, with 28 funds opening new positions, 91 increasing their positions, 83 reducing their positions, and 50 closing their positions.

New
Increased
Maintained
Reduced
Closed

28.12% more ownership

Funds ownership: 3.32%31.44% (+28%)

11% more call options, than puts

Call options by funds: $36.7M | Put options by funds: $33.2M

10% more repeat investments, than reductions

Existing positions increased: 91 | Existing positions reduced: 83

9% less funds holding

Funds holding: 267244 (-23)

11% less funds holding in top 10

Funds holding in top 10: 98 (-1)

28% less capital invested

Capital invested by funds: $11.6B → $8.34B (-$3.24B)

44% less first-time investments, than exits

New positions opened: 28 | Existing positions closed: 50

Holders
244
Holders Change
-23
Holders Change %
-8.61%
% of All Funds
3.21%
Holding in Top 10
8
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-11.11%
% of All Funds
0.11%
New
28
Increased
91
Reduced
83
Closed
50
Calls
$36.7M
Puts
$33.2M
Net Calls
+$3.51M
Net Calls Change
+$2.37M
Name Holding Trade Value Shares
Change
Change in
Stake
JFG
126
Jefferies Financial Group
New York
$702K
PCM
127
Penserra Capital Management
California
$702K -$1.51M -6,174 -68%
LPL Financial
128
LPL Financial
California
$697K +$135K +551 +24%
Cambridge Investment Research Advisors
129
Cambridge Investment Research Advisors
Iowa
$681K +$690K +2,815 New
Bank of New York Mellon
130
Bank of New York Mellon
New York
$671K -$736 -3 -0.1%
QCG
131
Quadrant Capital Group
Ohio
$630K +$583K +2,377 +1,047%
PWM
132
Perigon Wealth Management
California
$581K +$5.15K +21 +0.9%
YIH
133
Y-Intercept (HK)
Hong Kong
$564K +$571K +2,328 New
XC
134
XY Capital
Hong Kong
$559K -$14.3M -58,107 -96%
VPIM
135
Vanguard Personalized Indexing Management
California
$537K +$185K +753 +51%
BCI
136
Brinker Capital Investments
Pennsylvania
$524K +$531K +2,164 New
NW
137
NewEdge Wealth
Pennsylvania
$523K +$17.4K +71 +4%
BC
138
Bayforest Capital
United Kingdom
$520K +$250K +1,019 +90%
Arrowstreet Capital
139
Arrowstreet Capital
Massachusetts
$505K -$9.02M -36,777 -95%
FRM
140
Fox Run Management
Connecticut
$496K +$503K +2,050 New
Manulife (Manufacturers Life Insurance)
141
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$487K -$13.3M -54,236 -96%
TSS
142
Two Sigma Securities
New York
$480K +$487K +1,984 New
PCMH
143
Polymer Capital Management (HK)
Hong Kong
$460K +$466K +1,900 New
Cetera Investment Advisers
144
Cetera Investment Advisers
Illinois
$455K +$26K +106 +6%
Ameriprise
145
Ameriprise
Minnesota
$445K -$1,000K -4,076 -69%
VAS
146
Vestmark Advisory Solutions
Massachusetts
$445K -$368K -1,499 -45%
Invesco
147
Invesco
Georgia
$422K -$68.7K -280 -14%
P
148
&Partners
Tennessee
$413K +$51.7K +211 +14%
Pictet Asset Management
149
Pictet Asset Management
Switzerland
$412K +$199K +810 +91%
Kayne Anderson Rudnick Investment Management
150
Kayne Anderson Rudnick Investment Management
California
$396K +$363K +1,480 +955%

ONC Hedge Fund Activity: Q2 2025 in Review

244 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in BeOne Medicines Ltd (ONC) for Q2 2025, worth a combined $8.34B — down 28% from $11.6B a quarter earlier.

Sellers outnumbered buyers: 50 funds closed out of ONC and 28 opened new positions — a net loss of 22 holders — while 83 trimmed existing stakes and 91 added.

The largest buyer was UBS Group, adding an estimated $28.5M. The largest seller was Baillie Gifford & Co, exiting entirely with an estimated $988M sold.

  • 244 institutional investors held BeOne Medicines Ltd (ONC) as of Q2 2025, down from 267 in Q1 2025.
  • Funds reported $8.34B of BeOne Medicines Ltd stock for Q2 2025, down 28% quarter-over-quarter.
  • 28 funds opened new BeOne Medicines Ltd positions in Q2 2025 and 50 closed out, a net change of -22 holders.
  • The largest BeOne Medicines Ltd buyer in Q2 2025 was UBS Group, an estimated $28.5M added.
  • The largest BeOne Medicines Ltd seller in Q2 2025 was Baillie Gifford & Co, an estimated $988M sold.

Based on aggregated 13F filings for Q2 2025.