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NextCure
NXTC

24 hedge funds and large institutions have $26.9M invested in NextCure in 2025 Q4 according to their latest regulatory filings, with 9 funds opening new positions, 5 increasing their positions, 3 reducing their positions, and 2 closing their positions.

New
Increased
Maintained
Reduced
Closed

436% more capital invested

Capital invested by funds: $5.03M → $26.9M (+$21.9M)

350% more first-time investments, than exits

New positions opened: 9 | Existing positions closed: 2

67% more repeat investments, than reductions

Existing positions increased: 5 | Existing positions reduced: 3

41% more funds holding

Funds holding: 17 → 24 (+7)

22.06% more ownership

Funds ownership: 32.06% → 54.13% (+22%)

Holders
24
Holders Change
+7
Holders Change %
+41.18%
% of All Funds
0.29%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
9
Increased
5
Reduced
3
Closed
2
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

Rank Fund Capital Flow
1
IC
Ikarian Capital
Texas
+$2.47M
2
SCM
Silverarc Capital Management
Massachusetts
+$1.82M
3
EAM
Exome Asset Management
New York
+$1.71M
4
AIC
AWM Investment Company
New York
+$1.22M
5
BFM
Boothbay Fund Management
New York
+$721K

Top Sellers

Rank Fund Capital Flow
1
CCC
Cable Car Capital
California
-$370K
2
Acadian Asset Management
Acadian Asset Management
Massachusetts
-$103K
3
BlackRock
BlackRock
New York
-$34.1K
4
UBS Group
UBS Group
Switzerland
-$2.73K
5
Citigroup
Citigroup
New York
-$6
Name Holding Trade Value Shares
Change 		Change in
Stake
AAA
1
Affinity Asset Advisors
New York
$3.51M +$574K +55,412 +29%
IC
2
Ikarian Capital
Texas
$3.38M +$2.47M +238,303 New
SCM
3
Squadron Capital Management
Illinois
$3.36M +$2.46M +236,966 New
SI
4
Sofinnova Investments
California
$3.16M – – –
SCM
5
Silverarc Capital Management
Massachusetts
$2.5M +$1.82M +176,057 New
EAM
6
Exome Asset Management
New York
$2.34M +$1.71M +165,000 New
P
7
Pfizer
New York
$2.24M – – –
AIC
8
AWM Investment Company
New York
$1.67M +$1.22M +117,371 New
Vanguard Group
9
Vanguard Group
Pennsylvania
$1.3M +$248K +23,927 +35%
BFM
10
Boothbay Fund Management
New York
$988K +$721K +69,617 New
Renaissance Technologies
11
Renaissance Technologies
New York
$477K +$54.9K +5,300 +19%
BlackRock
12
BlackRock
New York
$394K -$34.1K -3,293 -11%
Acadian Asset Management
13
Acadian Asset Management
Massachusetts
$379K -$103K -9,910 -27%
Geode Capital Management
14
Geode Capital Management
Massachusetts
$329K +$37.7K +3,636 +19%
CPA
15
Cardiff Park Advisors
California
$310K – – –
Millennium Management
16
Millennium Management
New York
$185K +$135K +13,033 New
Marshall Wace
17
Marshall Wace
United Kingdom
$160K +$117K +11,292 New
SCM
18
Sio Capital Management
New York
$155K – – –
Barclays
19
Barclays
United Kingdom
$79.8K – – –
UBS Group
20
UBS Group
Switzerland
$4.8K -$2.73K -263 -44%
Bank of America
21
Bank of America
North Carolina
$2.45K +$1.55K +150 +652%
Morgan Stanley
22
Morgan Stanley
New York
$937 +$684 +66 New
JP Morgan Chase
23
JP Morgan Chase
New York
$866 – – –
BNP Paribas Financial Markets
24
BNP Paribas Financial Markets
France
$454 – – –
CCC
25
Cable Car Capital
California
– -$370K -63,178 Closed
1
2

NXTC Hedge Fund Activity: Q4 2025 in Review

24 of the 8,245 institutional investors tracked by Wall St. Rank reported a position in NextCure (NXTC) for Q4 2025, worth a combined $26.9M — up 436% from $5.03M a quarter earlier.

Buyers outnumbered sellers: 9 funds opened new NXTC positions and 2 closed out — a net gain of 7 holders — while 5 added to existing stakes and 3 trimmed.

The largest buyer was Ikarian Capital, opening a new position worth an estimated $2.47M. The largest seller was Cable Car Capital, exiting entirely with an estimated $370K sold.

  • 24 institutional investors held NextCure (NXTC) as of Q4 2025, up from 17 in Q3 2025.
  • Funds reported $26.9M of NextCure stock for Q4 2025, up 436% quarter-over-quarter.
  • 9 funds opened new NextCure positions in Q4 2025 and 2 closed out, a net change of +7 holders.
  • The largest NextCure buyer in Q4 2025 was Ikarian Capital, an estimated $2.47M added.
  • The largest NextCure seller in Q4 2025 was Cable Car Capital, an estimated $370K sold.

Based on aggregated 13F filings for Q4 2025.