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NUVL

Nuvalent
NUVL

Delisted

NUVL was delisted on the 14th of July, 2026.

205 hedge funds and large institutions have $5.11B invested in Nuvalent in 2025 Q1 according to their latest regulatory filings, with 24 funds opening new positions, 78 increasing their positions, 74 reducing their positions, and 35 closing their positions.

New
Increased
Maintained
Reduced
Closed

46% more call options, than puts

Call options by funds: $23.4M | Put options by funds: $16.1M

8% more funds holding in top 10

Funds holding in top 10: 1213 (+1)

1.34% more ownership

Funds ownership: 107.57%108.92% (+1.3%)

5% more repeat investments, than reductions

Existing positions increased: 78 | Existing positions reduced: 74

5% less funds holding

Funds holding: 216205 (-11)

8% less capital invested

Capital invested by funds: $5.53B → $5.11B (-$416M)

31% less first-time investments, than exits

New positions opened: 24 | Existing positions closed: 35

Holders
205
Holders Change
-11
Holders Change %
-5.09%
% of All Funds
2.75%
Holding in Top 10
13
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+8.33%
% of All Funds
0.17%
New
24
Increased
78
Reduced
74
Closed
35
Calls
$23.4M
Puts
$16.1M
Net Calls
+$7.37M
Net Calls Change
-$19.6M
Name Holding Trade Value Shares
Change
Change in
Stake
DM
1
Deerfield Management
New York
$1.28B
Fidelity Investments
2
Fidelity Investments
Massachusetts
$705M +$22.1M +282,867 +3%
PBA
3
Paradigm Biocapital Advisors
New York
$374M -$7.35M -93,946 -2%
Vanguard Group
4
Vanguard Group
Pennsylvania
$315M -$4.69M -60,026 -1%
BlackRock
5
BlackRock
New York
$266M -$8.07M -103,216 -3%
CC
6
Commodore Capital
New York
$132M +$18.2M +233,400 +14%
PA
7
Perceptive Advisors
New York
$116M -$77.1M -986,009 -38%
T. Rowe Price Associates
8
T. Rowe Price Associates
Maryland
$103M +$11.9M +152,692 +12%
BCLSI
9
Bain Capital Life Sciences Investors
Massachusetts
$103M
Wellington Management Group
10
Wellington Management Group
Massachusetts
$102M +$12.3M +157,809 +12%
State Street
11
State Street
Massachusetts
$101M -$4.61M -59,021 -4%
Janus Henderson Group
12
Janus Henderson Group
United Kingdom
$95.7M +$101M +1,293,580 +7,785%
WP
13
Woodline Partners
California
$85.5M +$47.2K +604 +0.1%
VPC
14
Vestal Point Capital
New York
$76.2M +$37.1M +475,000 +79%
PCH
15
Polar Capital Holdings
United Kingdom
$67.1M
Geode Capital Management
16
Geode Capital Management
Massachusetts
$63.4M +$1.72M +21,968 +3%
B
17
Braidwell
Connecticut
$59.6M +$46.9M +599,710 +249%
FFM
18
Fairmount Funds Management
Pennsylvania
$51.6M -$46.1M -590,101 -45%
Pictet Asset Management
19
Pictet Asset Management
Switzerland
$39.3M -$6.85M -87,640 -14%
DCM
20
Driehaus Capital Management
Illinois
$37.7M -$20.5M -262,206 -33%
LGM
21
Logos Global Management
California
$35.5M +$39.1M +500,000 New
AAA
22
Affinity Asset Advisors
New York
$32.6M +$13.7M +175,000 +61%
Goldman Sachs
23
Goldman Sachs
New York
$32.2M +$12.5M +159,873 +54%
T. Rowe Price Investment Management
24
T. Rowe Price Investment Management
Maryland
$32M +$35.2M +450,774 New
BCM
25
Boxer Capital Management
California
$31.9M -$52.4M -670,192 -60%

NUVL Hedge Fund Activity: Q1 2025 in Review

205 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Nuvalent (NUVL) for Q1 2025, worth a combined $5.11B — down 7.5% from $5.53B a quarter earlier.

Sellers outnumbered buyers: 35 funds closed out of NUVL and 24 opened new positions — a net loss of 11 holders — while 74 trimmed existing stakes and 78 added.

The largest buyer was Janus Henderson Group, adding an estimated $101M. The largest seller was Perceptive Advisors, cutting an estimated $77.1M.

  • 205 institutional investors held Nuvalent (NUVL) as of Q1 2025, down from 216 in Q4 2024.
  • Funds reported $5.11B of Nuvalent stock for Q1 2025, down 7.5% quarter-over-quarter.
  • 24 funds opened new Nuvalent positions in Q1 2025 and 35 closed out, a net change of -11 holders.
  • The largest Nuvalent buyer in Q1 2025 was Janus Henderson Group, an estimated $101M added.
  • The largest Nuvalent seller in Q1 2025 was Perceptive Advisors, an estimated $77.1M sold.

Based on aggregated 13F filings for Q1 2025.