Natera
NTRA
786 hedge funds and large institutions have $30.3B invested in Natera in 2025 Q4 according to their latest regulatory filings, with 186 funds opening new positions, 278 increasing their positions, 240 reducing their positions, and 63 closing their positions.
195% more first-time investments, than exits
New positions opened: 186 | Existing positions closed: 63
63% more funds holding in top 10
Funds holding in top 10: 16 → 26 (+10)
46% more capital invested
Capital invested by funds: $20.8B → $30.3B (+$9.48B)
41% more call options, than puts
Call options by funds: $117M | Put options by funds: $83.2M
16% more repeat investments, than reductions
Existing positions increased: 278 | Existing positions reduced: 240
15% more funds holding
Funds holding: 686 → 786 (+100)
1.37% more ownership
Funds ownership: 94.14% → 95.51% (+1.4%)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Coatue Management
New York
|
+$514M |
| 2 |
Wellington Management Group
Boston,
Massachusetts
|
+$505M |
| 3 |
JP Morgan Chase
New York
|
+$256M |
| 4 |
Arrowstreet Capital
Boston,
Massachusetts
|
+$130M |
| 5 |
T. Rowe Price Investment Management
Baltimore,
Maryland
|
+$104M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
T. Rowe Price Associates
Baltimore,
Maryland
|
-$224M |
| 2 |
Citadel Advisors
Miami,
Florida
|
-$164M |
| 3 |
DFO
Duquesne Family Office
New York
|
-$147M |
| 4 |
FAM
Fred Alger Management
New York
|
-$131M |
| 5 |
RI
RTW Investments
New York
|
-$104M |
NTRA Hedge Fund Activity: Q4 2025 in Review
786 of the 8,284 institutional investors tracked by Wall St. Rank reported a position in Natera (NTRA) for Q4 2025, worth a combined $30.3B — up 46% from $20.8B a quarter earlier.
Buyers outnumbered sellers: 186 funds opened new NTRA positions and 63 closed out — a net gain of 123 holders — while 278 added to existing stakes and 240 trimmed.
The largest buyer was Coatue Management, adding an estimated $514M. The largest seller was T. Rowe Price Associates, cutting an estimated $224M.
- 786 institutional investors held Natera (NTRA) as of Q4 2025, up from 686 in Q3 2025.
- Funds reported $30.3B of Natera stock for Q4 2025, up 46% quarter-over-quarter.
- 186 funds opened new Natera positions in Q4 2025 and 63 closed out, a net change of +123 holders.
- The largest Natera buyer in Q4 2025 was Coatue Management, an estimated $514M added.
- The largest Natera seller in Q4 2025 was T. Rowe Price Associates, an estimated $224M sold.
Based on aggregated 13F filings for Q4 2025.