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784 hedge funds and large institutions have $30.3B invested in Natera in 2025 Q4 according to their latest regulatory filings, with 184 funds opening new positions, 279 increasing their positions, 239 reducing their positions, and 63 closing their positions.

New
Increased
Maintained
Reduced
Closed

192% more first-time investments, than exits

New positions opened: 184 | Existing positions closed: 63

63% more funds holding in top 10

Funds holding in top 10: 1626 (+10)

46% more capital invested

Capital invested by funds: $20.8B → $30.3B (+$9.48B)

41% more call options, than puts

Call options by funds: $117M | Put options by funds: $83.2M

17% more repeat investments, than reductions

Existing positions increased: 279 | Existing positions reduced: 239

14% more funds holding

Funds holding: 686784 (+98)

1.37% more ownership

Funds ownership: 94.14%95.51% (+1.4%)

Holders
784
Holders Change
+98
Holders Change %
+14.29%
% of All Funds
9.54%
Holding in Top 10
26
Holding in Top 10 Change
+10
Holding in Top 10 Change %
+62.5%
% of All Funds
0.32%
New
184
Increased
279
Reduced
239
Closed
63
Calls
$117M
Puts
$83.2M
Net Calls
+$34.1M
Net Calls Change
-$78.8M
Name Holding Trade Value Shares
Change
Change in
Stake
JP Morgan Chase
1
JP Morgan Chase
New York
$2.94B +$256M +1,225,420 +11%
Vanguard Group
2
Vanguard Group
Pennsylvania
$2.82B -$17.2M -82,609 -0.7%
T. Rowe Price Associates
3
T. Rowe Price Associates
Maryland
$2.49B -$224M -1,075,426 -9%
BlackRock
4
BlackRock
New York
$2.49B -$21.9M -104,910 -1%
Wellington Management Group
5
Wellington Management Group
Massachusetts
$1.14B +$505M +2,420,263 +95%
FCM
6
Farallon Capital Management
California
$897M -$70.7M -339,086 -8%
State Street
7
State Street
Massachusetts
$739M -$34.2M -163,720 -5%
Coatue Management
8
Coatue Management
New York
$603M +$514M +2,463,008 +1,446%
Geode Capital Management
9
Geode Capital Management
Massachusetts
$596M +$2.44M +11,689 +0.5%
AQR Capital Management
10
AQR Capital Management
Connecticut
$595M +$41.6M +199,234 +8%
Franklin Resources
11
Franklin Resources
California
$581M -$27.2M -130,460 -5%
DFO
12
Duquesne Family Office
New York
$575M -$147M -703,175 -22%
CHP
13
Castle Hook Partners
New York
$497M +$87.7M +420,621 +24%
Massachusetts Financial Services
14
Massachusetts Financial Services
Massachusetts
$469M +$4.37M +20,927 +1%
FAM
15
Fred Alger Management
New York
$418M -$131M -629,271 -26%
Norges Bank
16
Norges Bank
Norway
$372M +$339M +1,625,553 New
SI
17
Sofinnova Investments
California
$355M
RI
18
RTW Investments
New York
$344M -$104M -500,000 -25%
Fidelity Investments
19
Fidelity Investments
Massachusetts
$338M +$75.6M +362,642 +33%
Capital World Investors
20
Capital World Investors
California
$328M +$4.25M +20,371 +1%
Invesco
21
Invesco
Georgia
$304M +$22.6M +108,437 +9%
Morgan Stanley
22
Morgan Stanley
New York
$283M -$10.3M -49,203 -4%
Lord, Abbett & Co
23
Lord, Abbett & Co
New Jersey
$279M +$23.1M +110,715 +10%
Arrowstreet Capital
24
Arrowstreet Capital
Massachusetts
$270M +$130M +620,954 +111%
Federated Hermes
25
Federated Hermes
Pennsylvania
$233M +$46.3M +222,161 +28%