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648 hedge funds and large institutions have $22.1B invested in Natera in 2025 Q2 according to their latest regulatory filings, with 109 funds opening new positions, 273 increasing their positions, 197 reducing their positions, and 55 closing their positions.

New
Increased
Maintained
Reduced
Closed

123% more call options, than puts

Call options by funds: $105M | Put options by funds: $47.1M

98% more first-time investments, than exits

New positions opened: 109 | Existing positions closed: 55

39% more repeat investments, than reductions

Existing positions increased: 273 | Existing positions reduced: 197

20% more capital invested

Capital invested by funds: $18.4B → $22.1B (+$3.67B)

8% more funds holding

Funds holding: 598648 (+50)

0.36% less ownership

Funds ownership: 96.22%95.86% (-0.36%)

21% less funds holding in top 10

Funds holding in top 10: 2419 (-5)

Holders
648
Holders Change
+50
Holders Change %
+8.36%
% of All Funds
8.53%
Holding in Top 10
19
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-20.83%
% of All Funds
0.25%
New
109
Increased
273
Reduced
197
Closed
55
Calls
$105M
Puts
$47.1M
Net Calls
+$57.8M
Net Calls Change
+$76.9M
Name Holding Trade Value Shares
Change
Change in
Stake
Allianz Asset Management
76
Allianz Asset Management
Germany
$34.9M -$7.1M -45,534 -18%
Royal Bank of Canada
77
Royal Bank of Canada
Ontario, Canada
$34.3M +$4.93M +31,648 +18%
SEI Investments
78
SEI Investments
Pennsylvania
$34.1M -$6.14M -39,400 -16%
CWG
79
C WorldWide Group
Denmark
$33.8M
APM
80
Avidity Partners Management
Texas
$33.7M +$12.5M +80,100 +67%
California State Teachers Retirement System (CalSTRS)
81
California State Teachers Retirement System (CalSTRS)
California
$33.4M +$7.48M +48,004 +32%
Barclays
82
Barclays
United Kingdom
$33.3M +$2.63M +16,848 +9%
Wells Fargo
83
Wells Fargo
California
$32.9M +$10.5M +67,642 +53%
A
84
AustralianSuper
Australia
$32.8M +$30.2M +194,026 New
MC
85
Maplelane Capital
New York
$31.6M +$16.7M +107,000 +134%
Schroder Investment Management Group
86
Schroder Investment Management Group
United Kingdom
$31.4M -$14.5M -92,804 -33%
Millennium Management
87
Millennium Management
New York
$29.8M -$12.3M -79,174 -31%
Handelsbanken Fonder
88
Handelsbanken Fonder
Sweden
$29.5M +$4.96M +31,800 +22%
D.E. Shaw & Co
89
D.E. Shaw & Co
New York
$29.4M -$10.8M -69,298 -29%
Envestnet Asset Management
90
Envestnet Asset Management
Illinois
$29.1M +$1.5M +9,651 +6%
Loomis, Sayles & Company
91
Loomis, Sayles & Company
Massachusetts
$28.8M -$12.9M -82,680 -33%
RhumbLine Advisers
92
RhumbLine Advisers
Massachusetts
$28.6M +$2.47M +15,847 +10%
BWLSA
93
Blue Water Life Science Advisors
California
$28.1M -$6.55M -42,000 -20%
Neuberger Berman Group
94
Neuberger Berman Group
New York
$27.9M +$243K +1,557 +1%
Citigroup
95
Citigroup
New York
$27.5M -$2.89M -18,514 -10%
Two Sigma Advisers
96
Two Sigma Advisers
New York
$25.8M +$810K +5,200 +4%
Mitsubishi UFJ Asset Management
97
Mitsubishi UFJ Asset Management
Japan
$25.4M +$1.39M +8,895 +6%
Amundi
98
Amundi
France
$25.2M -$53.5M -343,056 -69%
Ensign Peak Advisors
99
Ensign Peak Advisors
Utah
$25M +$4.8M +30,806 +26%
WorldQuant Millennium Advisors
100
WorldQuant Millennium Advisors
New York
$24.9M +$13.1M +83,882 +132%

NTRA Hedge Fund Activity: Q2 2025 in Review

648 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Natera (NTRA) for Q2 2025, worth a combined $22.1B — up 20% from $18.4B a quarter earlier.

Buyers outnumbered sellers: 109 funds opened new NTRA positions and 55 closed out — a net gain of 54 holders — while 273 added to existing stakes and 197 trimmed.

The largest buyer was JP Morgan Chase, adding an estimated $509M. The largest seller was Citadel Advisors, cutting an estimated $203M.

  • 648 institutional investors held Natera (NTRA) as of Q2 2025, up from 598 in Q1 2025.
  • Funds reported $22.1B of Natera stock for Q2 2025, up 20% quarter-over-quarter.
  • 109 funds opened new Natera positions in Q2 2025 and 55 closed out, a net change of +54 holders.
  • The largest Natera buyer in Q2 2025 was JP Morgan Chase, an estimated $509M added.
  • The largest Natera seller in Q2 2025 was Citadel Advisors, an estimated $203M sold.

Based on aggregated 13F filings for Q2 2025.