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686 hedge funds and large institutions have $20.8B invested in Natera in 2025 Q3 according to their latest regulatory filings, with 111 funds opening new positions, 268 increasing their positions, 230 reducing their positions, and 65 closing their positions.

New
Increased
Maintained
Reduced
Closed

143% more call options, than puts

Call options by funds: $192M | Put options by funds: $79M

71% more first-time investments, than exits

New positions opened: 111 | Existing positions closed: 65

17% more repeat investments, than reductions

Existing positions increased: 268 | Existing positions reduced: 230

6% more funds holding

Funds holding: 648686 (+38)

1.72% less ownership

Funds ownership: 95.86%94.14% (-1.7%)

6% less capital invested

Capital invested by funds: $22.1B → $20.8B (-$1.28B)

16% less funds holding in top 10

Funds holding in top 10: 1916 (-3)

Holders
686
Holders Change
+38
Holders Change %
+5.86%
% of All Funds
9%
Holding in Top 10
16
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-15.79%
% of All Funds
0.21%
New
111
Increased
268
Reduced
230
Closed
65
Calls
$192M
Puts
$79M
Net Calls
+$113M
Net Calls Change
+$55M
Name Holding Trade Value Shares
Change
Change in
Stake
GKIM
51
GW&K Investment Management
Massachusetts
$66.6M -$2.38M -15,035 -4%
First Trust Advisors
52
First Trust Advisors
Illinois
$65.8M -$740K -4,679 -1%
ZCI
53
Zevenbergen Capital Investments
Washington
$63.5M -$1.81M -11,417 -3%
Swiss National Bank
54
Swiss National Bank
Switzerland
$60.2M -$2.36M -14,900 -4%
FCM
55
Frontier Capital Management
Massachusetts
$59.4M -$2.52M -15,950 -4%
UBS Group
56
UBS Group
Switzerland
$59.2M +$2.5M +15,826 +5%
Dimensional Fund Advisors
57
Dimensional Fund Advisors
Texas
$58.4M +$5.81M +36,751 +11%
Balyasny Asset Management
58
Balyasny Asset Management
Illinois
$57.5M +$9.98M +63,060 +21%
VOYA Investment Management
59
VOYA Investment Management
Georgia
$57.4M -$205K -1,297 -0.4%
WorldQuant Millennium Advisors
60
WorldQuant Millennium Advisors
New York
$57.3M +$33M +208,283 +141%
Qube Research & Technologies (QRT)
61
Qube Research & Technologies (QRT)
United Kingdom
$56.6M +$23M +145,224 +70%
Ninety One (UK)
62
Ninety One (UK)
United Kingdom
$55.4M -$34.6M -218,812 -39%
AllianceBernstein
63
AllianceBernstein
Tennessee
$55M -$5.03M -31,795 -9%
Jennison Associates
64
Jennison Associates
New York
$54.8M -$8.56M -54,107 -14%
Legal & General Group
65
Legal & General Group
United Kingdom
$54.1M +$743K +4,698 +1%
Holocene Advisors
66
Holocene Advisors
New York
$51.8M -$39.7M -250,855 -44%
Royal Bank of Canada
67
Royal Bank of Canada
Ontario, Canada
$51.6M +$18.6M +117,575 +58%
Ameriprise
68
Ameriprise
Minnesota
$49.6M -$99.1M -626,686 -67%
RCMU
69
Rokos Capital Management (UK)
United Kingdom
$49.3M
Assenagon Asset Management
70
Assenagon Asset Management
Luxembourg
$49.2M +$12.8M +80,684 +36%
Renaissance Technologies
71
Renaissance Technologies
New York
$48M -$30.9M -195,300 -40%
Wells Fargo
72
Wells Fargo
California
$46.6M +$15M +94,522 +49%
Amundi
73
Amundi
France
$45.4M +$17.5M +110,824 +71%
Two Sigma Investments
74
Two Sigma Investments
New York
$45.3M +$4.61M +29,122 +12%
PAM
75
Panagora Asset Management
Massachusetts
$44.5M +$29.2M +184,697 +201%

NTRA Hedge Fund Activity: Q3 2025 in Review

686 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Natera (NTRA) for Q3 2025, worth a combined $20.8B — down 5.8% from $22.1B a quarter earlier.

Buyers outnumbered sellers: 111 funds opened new NTRA positions and 65 closed out — a net gain of 46 holders — while 268 added to existing stakes and 230 trimmed.

The largest buyer was JP Morgan Chase, adding an estimated $159M. The largest seller was Invesco, cutting an estimated $103M.

  • 686 institutional investors held Natera (NTRA) as of Q3 2025, up from 648 in Q2 2025.
  • Funds reported $20.8B of Natera stock for Q3 2025, down 5.8% quarter-over-quarter.
  • 111 funds opened new Natera positions in Q3 2025 and 65 closed out, a net change of +46 holders.
  • The largest Natera buyer in Q3 2025 was JP Morgan Chase, an estimated $159M added.
  • The largest Natera seller in Q3 2025 was Invesco, an estimated $103M sold.

Based on aggregated 13F filings for Q3 2025.