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648 hedge funds and large institutions have $22.1B invested in Natera in 2025 Q2 according to their latest regulatory filings, with 109 funds opening new positions, 273 increasing their positions, 197 reducing their positions, and 55 closing their positions.

New
Increased
Maintained
Reduced
Closed

123% more call options, than puts

Call options by funds: $105M | Put options by funds: $47.1M

98% more first-time investments, than exits

New positions opened: 109 | Existing positions closed: 55

39% more repeat investments, than reductions

Existing positions increased: 273 | Existing positions reduced: 197

20% more capital invested

Capital invested by funds: $18.4B → $22.1B (+$3.67B)

8% more funds holding

Funds holding: 598648 (+50)

0.36% less ownership

Funds ownership: 96.22%95.86% (-0.36%)

21% less funds holding in top 10

Funds holding in top 10: 2419 (-5)

Holders
648
Holders Change
+50
Holders Change %
+8.36%
% of All Funds
8.53%
Holding in Top 10
19
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-20.83%
% of All Funds
0.25%
New
109
Increased
273
Reduced
197
Closed
55
Calls
$105M
Puts
$47.1M
Net Calls
+$57.8M
Net Calls Change
+$76.9M
Name Holding Trade Value Shares
Change
Change in
Stake
Renaissance Technologies
51
Renaissance Technologies
New York
$83.4M +$22.8M +146,100 +42%
Arrowstreet Capital
52
Arrowstreet Capital
Massachusetts
$81.6M +$17.1M +109,417 +29%
GKIM
53
GW&K Investment Management
Massachusetts
$72.4M +$14.9M +95,891 +29%
First Trust Advisors
54
First Trust Advisors
Illinois
$69.9M -$626K -4,016 -1%
ZCI
55
Zevenbergen Capital Investments
Washington
$68.6M -$3.69M -23,683 -6%
Jennison Associates
56
Jennison Associates
New York
$66.6M -$671K -4,304 -1%
Swiss National Bank
57
Swiss National Bank
Switzerland
$65.7M +$5.45M +35,000 +10%
FCM
58
Frontier Capital Management
Massachusetts
$65M -$2.14M -13,712 -3%
AllianceBernstein
59
AllianceBernstein
Tennessee
$63.1M -$65.2M -418,694 -53%
VOYA Investment Management
60
VOYA Investment Management
Georgia
$60.5M +$11.3M +72,709 +25%
UBS Group
61
UBS Group
Switzerland
$59.4M -$106K -680 -0.2%
ClearBridge Investments
62
ClearBridge Investments
New York
$57.8M +$3.78M +24,283 +8%
Legal & General Group
63
Legal & General Group
United Kingdom
$56M +$12.1M +77,547 +31%
Dimensional Fund Advisors
64
Dimensional Fund Advisors
Texas
$55.1M +$5.4M +34,661 +12%
RCMU
65
Rokos Capital Management (UK)
United Kingdom
$51.8M
Balyasny Asset Management
66
Balyasny Asset Management
Illinois
$49.7M -$16.9M -108,500 -27%
Deutsche Bank
67
Deutsche Bank
Germany
$45.6M +$3.66M +23,455 +10%
Two Sigma Investments
68
Two Sigma Investments
New York
$42.6M +$27.4M +175,999 +230%
SC
69
Samlyn Capital
New York
$40.3M +$447K +2,869 +1%
EHI
70
Eagle Health Investments
Connecticut
$39.9M -$6.83M -43,800 -16%
Point72 Asset Management
71
Point72 Asset Management
Connecticut
$39.7M -$60.7M -389,781 -62%
JF
72
Jump Financial
Illinois
$39.7M +$2.93M +18,821 +9%
Assenagon Asset Management
73
Assenagon Asset Management
Luxembourg
$38M -$32.1M -205,730 -48%
California Public Employees Retirement System
74
California Public Employees Retirement System
California
$36.7M +$4.57M +29,296 +16%
Qube Research & Technologies (QRT)
75
Qube Research & Technologies (QRT)
United Kingdom
$34.9M -$45M -288,742 -58%

NTRA Hedge Fund Activity: Q2 2025 in Review

648 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Natera (NTRA) for Q2 2025, worth a combined $22.1B — up 20% from $18.4B a quarter earlier.

Buyers outnumbered sellers: 109 funds opened new NTRA positions and 55 closed out — a net gain of 54 holders — while 273 added to existing stakes and 197 trimmed.

The largest buyer was JP Morgan Chase, adding an estimated $509M. The largest seller was Citadel Advisors, cutting an estimated $203M.

  • 648 institutional investors held Natera (NTRA) as of Q2 2025, up from 598 in Q1 2025.
  • Funds reported $22.1B of Natera stock for Q2 2025, up 20% quarter-over-quarter.
  • 109 funds opened new Natera positions in Q2 2025 and 55 closed out, a net change of +54 holders.
  • The largest Natera buyer in Q2 2025 was JP Morgan Chase, an estimated $509M added.
  • The largest Natera seller in Q2 2025 was Citadel Advisors, an estimated $203M sold.

Based on aggregated 13F filings for Q2 2025.