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686 hedge funds and large institutions have $20.8B invested in Natera in 2025 Q3 according to their latest regulatory filings, with 111 funds opening new positions, 268 increasing their positions, 230 reducing their positions, and 65 closing their positions.

New
Increased
Maintained
Reduced
Closed

143% more call options, than puts

Call options by funds: $192M | Put options by funds: $79M

71% more first-time investments, than exits

New positions opened: 111 | Existing positions closed: 65

17% more repeat investments, than reductions

Existing positions increased: 268 | Existing positions reduced: 230

6% more funds holding

Funds holding: 648686 (+38)

1.72% less ownership

Funds ownership: 95.86%94.14% (-1.7%)

6% less capital invested

Capital invested by funds: $22.1B → $20.8B (-$1.28B)

16% less funds holding in top 10

Funds holding in top 10: 1916 (-3)

Holders
686
Holders Change
+38
Holders Change %
+5.86%
% of All Funds
9%
Holding in Top 10
16
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-15.79%
% of All Funds
0.21%
New
111
Increased
268
Reduced
230
Closed
65
Calls
$192M
Puts
$79M
Net Calls
+$113M
Net Calls Change
+$55M
Name Holding Trade Value Shares
Change
Change in
Stake
Citadel Advisors
26
Citadel Advisors
Florida
$144M +$11.9M +75,221 +9%
AIM
27
ARK Investment Management
Florida
$144M -$6.93M -43,799 -5%
Sumitomo Mitsui Trust Group
28
Sumitomo Mitsui Trust Group
Japan
$142M -$14.1M -88,968 -9%
American Century Companies
29
American Century Companies
Missouri
$136M +$37.8M +238,679 +39%
NM
30
NWI Management
New York
$134M -$3.02M -19,117 -2%
ClearBridge Investments
31
ClearBridge Investments
New York
$129M +$72.6M +459,178 +134%
Federated Hermes
32
Federated Hermes
Pennsylvania
$128M +$4.62M +29,221 +4%
UBS AM
33
UBS AM
Illinois
$123M -$23M -145,656 -16%
Bank of America
34
Bank of America
North Carolina
$123M +$25.6M +161,972 +27%
Northern Trust
35
Northern Trust
Illinois
$120M +$1.32M +8,322 +1%
N
36
Nuveen
North Carolina
$105M -$9.65M -60,995 -9%
Raymond James Financial
37
Raymond James Financial
Florida
$105M -$28.7M -181,633 -22%
Charles Schwab
38
Charles Schwab
California
$104M -$51.2M -323,730 -33%
Bank of New York Mellon
39
Bank of New York Mellon
New York
$103M -$9.72M -61,469 -9%
NAMA
40
Nikko Asset Management Americas
New York
$101M -$14.3M -90,468 -13%
Chevy Chase Trust
41
Chevy Chase Trust
Maryland
$96.4M +$302K +1,907 +0.3%
Victory Capital Management
42
Victory Capital Management
Texas
$95.5M -$26.1M -165,275 -22%
DCM
43
Driehaus Capital Management
Illinois
$94.4M -$63.1M -398,937 -40%
Westfield Capital Management
44
Westfield Capital Management
Massachusetts
$92.7M -$14.9M -94,087 -14%
Arrowstreet Capital
45
Arrowstreet Capital
Massachusetts
$90M +$12M +75,750 +16%
Millennium Management
46
Millennium Management
New York
$85M +$55.6M +351,433 +199%
EP
47
Eversept Partners
New York
$83.6M -$43.8M -276,731 -35%
Allspring Global Investments
48
Allspring Global Investments
North Carolina
$76.8M -$7.46M -47,131 -9%
Principal Financial Group
49
Principal Financial Group
Iowa
$69.1M -$29M -183,106 -30%
O
50
OrbiMed
New York
$69.1M -$26M -164,134 -28%

NTRA Hedge Fund Activity: Q3 2025 in Review

686 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Natera (NTRA) for Q3 2025, worth a combined $20.8B — down 5.8% from $22.1B a quarter earlier.

Buyers outnumbered sellers: 111 funds opened new NTRA positions and 65 closed out — a net gain of 46 holders — while 268 added to existing stakes and 230 trimmed.

The largest buyer was JP Morgan Chase, adding an estimated $159M. The largest seller was Invesco, cutting an estimated $103M.

  • 686 institutional investors held Natera (NTRA) as of Q3 2025, up from 648 in Q2 2025.
  • Funds reported $20.8B of Natera stock for Q3 2025, down 5.8% quarter-over-quarter.
  • 111 funds opened new Natera positions in Q3 2025 and 65 closed out, a net change of +46 holders.
  • The largest Natera buyer in Q3 2025 was JP Morgan Chase, an estimated $159M added.
  • The largest Natera seller in Q3 2025 was Invesco, an estimated $103M sold.

Based on aggregated 13F filings for Q3 2025.