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686 hedge funds and large institutions have $20.8B invested in Natera in 2025 Q3 according to their latest regulatory filings, with 111 funds opening new positions, 268 increasing their positions, 230 reducing their positions, and 65 closing their positions.

New
Increased
Maintained
Reduced
Closed

143% more call options, than puts

Call options by funds: $192M | Put options by funds: $79M

71% more first-time investments, than exits

New positions opened: 111 | Existing positions closed: 65

17% more repeat investments, than reductions

Existing positions increased: 268 | Existing positions reduced: 230

6% more funds holding

Funds holding: 648686 (+38)

1.72% less ownership

Funds ownership: 95.86%94.14% (-1.7%)

6% less capital invested

Capital invested by funds: $22.1B → $20.8B (-$1.28B)

16% less funds holding in top 10

Funds holding in top 10: 1916 (-3)

Holders
686
Holders Change
+38
Holders Change %
+5.86%
% of All Funds
9%
Holding in Top 10
16
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-15.79%
% of All Funds
0.21%
New
111
Increased
268
Reduced
230
Closed
65
Calls
$192M
Puts
$79M
Net Calls
+$113M
Net Calls Change
+$55M
Name Holding Trade Value Shares
Change
Change in
Stake
MSRPS
351
Maryland State Retirement & Pension System
Maryland
$1.02M
N
352
Natixis
France
$1.01M +$989K +6,251 New
NERM
353
New England Research & Management
Illinois
$1M +$740K +4,675 +302%
BEI
354
Benjamin Edwards Inc
Missouri
$999K -$24.2K -153 -2%
YIH
355
Y-Intercept (HK)
Hong Kong
$991K -$610K -3,854 -39%
IMCOOI
356
Investment Management Corp of Ontario (IMCO)
Canada
$983K +$476K +3,008 +97%
BHCM
357
Brevan Howard Capital Management
Jersey
$953K +$569K +3,597 +155%
FDCDDQ
358
Federation des caisses Desjardins du Quebec
Quebec, Canada
$934K +$21.4K +135 +2%
Calamos Advisors
359
Calamos Advisors
Illinois
$930K -$3.22M -20,345 -78%
US Bancorp
360
US Bancorp
Minnesota
$925K -$306K -1,932 -25%
PCM
361
Prelude Capital Management
New York
$922K +$42.1K +266 +5%
William Blair & Company
362
William Blair & Company
Illinois
$920K +$474K +2,999 +110%
Robeco Institutional Asset Management
363
Robeco Institutional Asset Management
Netherlands
$912K -$947K -5,989 -51%
NAM
364
NorthCrest Asset Manangement
Minnesota
$900K +$498K +3,146 +143%
M&T Bank
365
M&T Bank
New York
$897K -$160K -1,009 -15%
SF
366
Summit Financial
New Jersey
$890K +$875K +5,532 New
Royal London Asset Management
367
Royal London Asset Management
United Kingdom
$886K
GCS
368
Gordian Capital (Singapore)
Singapore
$853K -$364K -2,300 -30%
AFM
369
Abbot Financial Management
Massachusetts
$853K +$16.3K +103 +2%
I
370
InceptionR
California
$829K -$272K -1,719 -25%
CCIA
371
Campbell & Co Investment Adviser
Maryland
$828K +$814K +5,145 New
IFO
372
Intrepid Family Office
Florida
$805K -$79.1K -500 -9%
DILIC
373
Dai-ichi Life Insurance Company
Japan
$778K
AC
374
Allstate Corporation
Illinois
$775K +$762K +4,816 New
Brown Advisory
375
Brown Advisory
Maryland
$753K +$28.3K +179 +4%

NTRA Hedge Fund Activity: Q3 2025 in Review

686 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Natera (NTRA) for Q3 2025, worth a combined $20.8B — down 5.8% from $22.1B a quarter earlier.

Buyers outnumbered sellers: 111 funds opened new NTRA positions and 65 closed out — a net gain of 46 holders — while 268 added to existing stakes and 230 trimmed.

The largest buyer was JP Morgan Chase, adding an estimated $159M. The largest seller was Invesco, cutting an estimated $103M.

  • 686 institutional investors held Natera (NTRA) as of Q3 2025, up from 648 in Q2 2025.
  • Funds reported $20.8B of Natera stock for Q3 2025, down 5.8% quarter-over-quarter.
  • 111 funds opened new Natera positions in Q3 2025 and 65 closed out, a net change of +46 holders.
  • The largest Natera buyer in Q3 2025 was JP Morgan Chase, an estimated $159M added.
  • The largest Natera seller in Q3 2025 was Invesco, an estimated $103M sold.

Based on aggregated 13F filings for Q3 2025.