|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$112M
|
+$140M
|
+5,254,407
|
New
|
|
|
2
|
|
$56.8M
|
+$70.8M
|
+2,662,180
|
New
|
|
|
3
|
Baker Bros. Advisors
New York
|
$22.7M
|
+$28.3M
|
+1,062,120
|
New
|
|
|
4
|
Temasek Holdings
Singapore
|
$16.9M
|
+$21M
|
+790,527
|
New
|
|
|
5
|
Foresite Capital Management III
Larkspur,
California
|
$16.3M
|
+$20.3M
|
+763,688
|
New
|
|
|
6
|
BlackRock Advisors
Wilmington,
Delaware
|
$13.1M
|
+$16.4M
|
+615,749
|
New
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$8.89M
|
+$11.1M
|
+416,564
|
New
|
|
|
8
|
EcoR1 Capital
San Francisco,
California
|
$6.63M
|
+$8.27M
|
+310,695
|
New
|
|
|
9
|
|
$6.43M
|
+$8.02M
|
+301,358
|
New
|
|
|
10
|
Franklin Resources
San Mateo,
California
|
$6.41M
|
+$7.98M
|
+300,000
|
New
|
|
|
11
|
|
$4.8M
|
+$5.99M
|
+225,000
|
New
|
|
|
12
|
BlackRock Fund Advisors
San Francisco,
California
|
$3.5M
|
+$4.36M
|
+163,768
|
New
|
|
|
13
|
|
$3.07M
|
+$3.83M
|
+144,002
|
New
|
|
|
14
|
Tekla Capital Management
Boston,
Massachusetts
|
$1.85M
|
+$2.31M
|
+86,842
|
New
|
|
|
15
|
|
$1.77M
|
+$2.21M
|
+82,994
|
New
|
|
|
16
|
Neuberger Berman Group
New York
|
$1.65M
|
+$2.06M
|
+77,486
|
New
|
|
|
17
|
Northern Trust
Chicago,
Illinois
|
$1.61M
|
+$2.01M
|
+75,683
|
New
|
|
|
18
|
State Street
Boston,
Massachusetts
|
$1.51M
|
+$1.89M
|
+70,874
|
New
|
|
|
19
|
Sectoral Asset Management
Montreal,
Quebec, Canada
|
$1.47M
|
+$3.28M
|
+123,159
|
New
|
|
|
20
|
Geode Capital Management
Boston,
Massachusetts
|
$1.44M
|
+$1.79M
|
+67,346
|
New
|
|
|
21
|
Emerald Acquisition
Seattle,
Washington
|
$1.3M
|
+$1.62M
|
+60,954
|
New
|
|
|
22
|
|
$1.3M
|
+$1.62M
|
+60,925
|
New
|
|
|
23
|
BlackRock Institutional Trust
San Francisco,
California
|
$1.24M
|
+$1.54M
|
+57,913
|
New
|
|
|
24
|
|
$730K
|
+$909K
|
+34,176
|
New
|
|
|
25
|
Landscape Capital Management
Englewood,
New Jersey
|
$582K
|
+$725K
|
+27,268
|
New
|
|
