|
1
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$107M
|
+$28.1M
|
+957,773
|
+31%
|
|
|
2
|
TRV GP III
Boston,
Massachusetts
|
$90.8M
|
-$31.9M
|
-1,085,784
|
-24%
|
|
|
3
|
Redmile Group
San Francisco,
California
|
$84.6M
|
-$3.64M
|
-124,040
|
-4%
|
|
|
4
|
Baker Bros. Advisors
New York
|
$65.1M
|
–
|
–
|
–
|
|
|
5
|
|
$55.4M
|
+$7.92M
|
+269,927
|
+15%
|
|
|
6
|
EcoR1 Capital
San Francisco,
California
|
$52.2M
|
-$1.5M
|
-51,069
|
-3%
|
|
|
7
|
State Street
Boston,
Massachusetts
|
$49.3M
|
+$14.1M
|
+481,606
|
+35%
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$38.9M
|
+$8.9M
|
+303,153
|
+26%
|
|
|
9
|
Wellington Management Group
Boston,
Massachusetts
|
$37M
|
+$1.01M
|
+34,465
|
+3%
|
|
|
10
|
Bain Capital Life Sciences Investors
Boston,
Massachusetts
|
$34.1M
|
–
|
–
|
–
|
|
|
11
|
Boxer Capital
San Diego,
California
|
$32.5M
|
–
|
–
|
–
|
|
|
12
|
Foresite Capital Management IV
Larkspur,
California
|
$32M
|
-$959K
|
-32,658
|
-3%
|
|
|
13
|
Eventide Asset Management
Boston,
Massachusetts
|
$31.8M
|
–
|
–
|
–
|
|
|
14
|
Wasatch Advisors
Salt Lake City,
Utah
|
$31.7M
|
+$4.67M
|
+158,914
|
+15%
|
|
|
15
|
Jennison Associates
New York
|
$24.4M
|
-$28.1K
|
-957
|
-0.1%
|
|
|
16
|
Ponoi II Management
San Francisco,
California
|
$18.2M
|
–
|
–
|
–
|
|
|
17
|
Ponoi Management
San Francisco,
California
|
$18.2M
|
–
|
–
|
–
|
|
|
18
|
Pictet Asset Management (UK)
London,
United Kingdom
|
$18M
|
+$8.15M
|
+277,491
|
+69%
|
|
|
19
|
Fidelity Investments
Boston,
Massachusetts
|
$17.5M
|
+$2.33M
|
+79,532
|
+14%
|
|
|
20
|
Regents of the University of California
Oakland,
California
|
$15.2M
|
+$16.8M
|
+571,212
|
New
|
|
|
21
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$13.5M
|
+$14.9M
|
+507,290
|
+3,902,231%
|
|
|
22
|
Foresite Capital Management V
Larkspur,
California
|
$12M
|
–
|
–
|
–
|
|
|
23
|
|
$11.8M
|
+$10.2M
|
+348,995
|
+371%
|
|
|
24
|
Millennium Management
New York
|
$11.3M
|
+$5.46M
|
+186,051
|
+78%
|
|
|
25
|
Geode Capital Management
Boston,
Massachusetts
|
$10.5M
|
+$2.09M
|
+71,237
|
+22%
|
|
