We are live on ! Find out more
NRIX icon

Nurix Therapeutics

182 hedge funds and large institutions have $2.15B invested in Nurix Therapeutics in 2025 Q4 according to their latest regulatory filings, with 39 funds opening new positions, 93 increasing their positions, 29 reducing their positions, and 28 closing their positions.

New
Increased
Maintained
Reduced
Closed

300% more funds holding in top 10

Funds holding in top 10: 14 (+3)

221% more repeat investments, than reductions

Existing positions increased: 93 | Existing positions reduced: 29

192% more call options, than puts

Call options by funds: $4.74M | Put options by funds: $1.63M

175% more capital invested

Capital invested by funds: $783M → $2.15B (+$1.37B)

39% more first-time investments, than exits

New positions opened: 39 | Existing positions closed: 28

36.63% more ownership

Funds ownership: 110.89%147.52% (+37%)

5% more funds holding

Funds holding: 173182 (+9)

Holders
182
Holders Change
+9
Holders Change %
+5.2%
% of All Funds
2.21%
Holding in Top 10
4
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+300%
% of All Funds
0.05%
New
39
Increased
93
Reduced
29
Closed
28
Calls
$4.74M
Puts
$1.63M
Net Calls
+$3.12M
Net Calls Change
+$2.1M
Name Holding Trade Value Shares
Change
Change in
Stake
BlackRock
1
BlackRock
New York
$168M +$30.3M +2,112,608 +31%
RG
2
Redmile Group
California
$154M +$63.4M +4,415,514 +120%
DTC
3
Deep Track Capital
Connecticut
$133M +$14.1M +979,431 +16%
Vanguard Group
4
Vanguard Group
Pennsylvania
$113M +$21M +1,460,736 +33%
GA
5
General Atlantic
New York
$92.9M +$70.4M +4,897,159 New
Morgan Stanley
6
Morgan Stanley
New York
$92.6M +$37.6M +2,620,323 +116%
VPC
7
Vestal Point Capital
New York
$89M +$17.5M +1,215,000 +35%
BBA
8
Baker Bros. Advisors
New York
$88.4M +$11.2M +776,431 +20%
Fidelity Investments
9
Fidelity Investments
Massachusetts
$80.3M -$66.8M -4,653,379 -52%
State Street
10
State Street
Massachusetts
$67.5M +$10M +697,114 +24%
PA
11
Perceptive Advisors
New York
$67.5M +$30.7M +2,139,728 +151%
Pictet Asset Management
12
Pictet Asset Management
Switzerland
$65.8M +$21.4M +1,487,060 +75%
T. Rowe Price Associates
13
T. Rowe Price Associates
Maryland
$61.6M +$30.9M +2,149,268 +196%
Point72 Asset Management
14
Point72 Asset Management
Connecticut
$60.9M +$4.89M +340,183 +12%
Deutsche Bank
15
Deutsche Bank
Germany
$47.2M +$15.1M +1,047,933 +73%
RCMNY
16
Rubric Capital Management (New York)
New York
$46.9M +$35.5M +2,473,885 New
Geode Capital Management
17
Geode Capital Management
Massachusetts
$45.3M +$7.22M +502,316 +27%
CC
18
Commodore Capital
New York
$43.2M -$21.6M -1,505,055 -40%
B
19
Braidwell
Connecticut
$41.4M +$31.4M +2,183,864 New
KCM
20
Kynam Capital Management
New Jersey
$37.4M -$2.85M -198,248 -9%
TECP
21
Trails Edge Capital Partners
Georgia
$33.1M +$25M +1,743,220 New
AIM
22
ARK Investment Management
Florida
$30.4M +$1.32M +92,135 +6%
EAM
23
Eventide Asset Management
Massachusetts
$24.6M +$18.6M +1,297,893 New
NAMA
24
Nikko Asset Management Americas
New York
$24.5M -$3.83M -266,925 -17%
Sumitomo Mitsui Trust Group
25
Sumitomo Mitsui Trust Group
Japan
$24.5M -$3.83M -266,925 -17%

NRIX Hedge Fund Activity: Q4 2025 in Review

182 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Nurix Therapeutics (NRIX) for Q4 2025, worth a combined $2.15B — up 175% from $783M a quarter earlier.

Buyers outnumbered sellers: 39 funds opened new NRIX positions and 28 closed out — a net gain of 11 holders — while 93 added to existing stakes and 29 trimmed.

The largest buyer was General Atlantic, opening a new position worth an estimated $70.4M. The largest seller was Fidelity Investments, cutting an estimated $66.8M.

  • 182 institutional investors held Nurix Therapeutics (NRIX) as of Q4 2025, up from 173 in Q3 2025.
  • Funds reported $2.15B of Nurix Therapeutics stock for Q4 2025, up 175% quarter-over-quarter.
  • 39 funds opened new Nurix Therapeutics positions in Q4 2025 and 28 closed out, a net change of +11 holders.
  • The largest Nurix Therapeutics buyer in Q4 2025 was General Atlantic, an estimated $70.4M added.
  • The largest Nurix Therapeutics seller in Q4 2025 was Fidelity Investments, an estimated $66.8M sold.

Based on aggregated 13F filings for Q4 2025.