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Nurix Therapeutics

182 hedge funds and large institutions have $2.15B invested in Nurix Therapeutics in 2025 Q4 according to their latest regulatory filings, with 39 funds opening new positions, 93 increasing their positions, 29 reducing their positions, and 28 closing their positions.

New
Increased
Maintained
Reduced
Closed

300% more funds holding in top 10

Funds holding in top 10: 14 (+3)

221% more repeat investments, than reductions

Existing positions increased: 93 | Existing positions reduced: 29

192% more call options, than puts

Call options by funds: $4.74M | Put options by funds: $1.63M

175% more capital invested

Capital invested by funds: $783M → $2.15B (+$1.37B)

39% more first-time investments, than exits

New positions opened: 39 | Existing positions closed: 28

36.63% more ownership

Funds ownership: 110.89%147.52% (+37%)

5% more funds holding

Funds holding: 173182 (+9)

Holders
182
Holders Change
+9
Holders Change %
+5.2%
% of All Funds
2.21%
Holding in Top 10
4
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+300%
% of All Funds
0.05%
New
39
Increased
93
Reduced
29
Closed
28
Calls
$4.74M
Puts
$1.63M
Net Calls
+$3.12M
Net Calls Change
+$2.1M
Name Holding Trade Value Shares
Change
Change in
Stake
SCM
26
Soleus Capital Management
Connecticut
$23.1M -$17.3M -1,203,439 -50%
Citadel Advisors
27
Citadel Advisors
Florida
$21.9M +$8.44M +587,625 +104%
Goldman Sachs
28
Goldman Sachs
New York
$20.4M +$6.54M +455,274 +73%
AAA
29
Affinity Asset Advisors
New York
$18.4M
Charles Schwab
30
Charles Schwab
California
$18.3M +$1.46M +101,512 +12%
LP
31
Longaeva Partners
Illinois
$17.6M +$13.3M +927,729 New
WP
32
Woodline Partners
California
$17.6M +$12.2M +848,900 +1,109%
Northern Trust
33
Northern Trust
Illinois
$15.3M +$1.81M +125,673 +18%
N
34
Nuveen
North Carolina
$14.9M +$9.08M +632,349 +416%
Bank of America
35
Bank of America
North Carolina
$14M +$3.67M +255,504 +53%
Jacobs Levy Equity Management
36
Jacobs Levy Equity Management
New Jersey
$13.9M +$9.93M +691,311 +1,576%
Handelsbanken Fonder
37
Handelsbanken Fonder
Sweden
$10.4M +$388K +27,000 +5%
RPAM
38
Rhenman & Partners Asset Management
Sweden
$10.2M +$2.73M +190,000 +55%
CS
39
Candriam SCA
Luxembourg
$10.1M +$3.91M +271,875 +104%
LGM
40
Logos Global Management
California
$9.48M +$7.18M +500,000 New
EC
41
Elmind Capital
New York
$8.73M +$6.61M +460,000 New
Dimensional Fund Advisors
42
Dimensional Fund Advisors
Texas
$8.18M +$345 +24 +0%
UBS Group
43
UBS Group
Switzerland
$8.03M +$875K +60,879 +17%
Invesco
44
Invesco
Georgia
$6.52M +$2.64M +183,909 +115%
ACH
45
ArrowMark Colorado Holdings
Colorado
$5.97M
Bessemer Group
46
Bessemer Group
New Jersey
$5.8M
IHAM
47
Integral Health Asset Management
New York
$5.69M -$718K -50,000 -14%
Bank of New York Mellon
48
Bank of New York Mellon
New York
$5.47M +$853K +59,385 +26%
Wellington Management Group
49
Wellington Management Group
Massachusetts
$5.22M +$279K +19,388 +8%
KCM
50
Kennedy Capital Management
Missouri
$4.96M +$208K +14,461 +6%

NRIX Hedge Fund Activity: Q4 2025 in Review

182 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Nurix Therapeutics (NRIX) for Q4 2025, worth a combined $2.15B — up 175% from $783M a quarter earlier.

Buyers outnumbered sellers: 39 funds opened new NRIX positions and 28 closed out — a net gain of 11 holders — while 93 added to existing stakes and 29 trimmed.

The largest buyer was General Atlantic, opening a new position worth an estimated $70.4M. The largest seller was Fidelity Investments, cutting an estimated $66.8M.

  • 182 institutional investors held Nurix Therapeutics (NRIX) as of Q4 2025, up from 173 in Q3 2025.
  • Funds reported $2.15B of Nurix Therapeutics stock for Q4 2025, up 175% quarter-over-quarter.
  • 39 funds opened new Nurix Therapeutics positions in Q4 2025 and 28 closed out, a net change of +11 holders.
  • The largest Nurix Therapeutics buyer in Q4 2025 was General Atlantic, an estimated $70.4M added.
  • The largest Nurix Therapeutics seller in Q4 2025 was Fidelity Investments, an estimated $66.8M sold.

Based on aggregated 13F filings for Q4 2025.