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Nkarta
NKTX

119 hedge funds and large institutions have $103M invested in Nkarta in 2025 Q4 according to their latest regulatory filings, with 15 funds opening new positions, 35 increasing their positions, 40 reducing their positions, and 12 closing their positions.

New
Increased
Maintained
Reduced
Closed

25% more first-time investments, than exits

New positions opened: 15 | Existing positions closed: 12

1% less funds holding

Funds holding: 120 → 119 (-1)

2.74% less ownership

Funds ownership: 81.22% → 78.48% (-2.7%)

13% less repeat investments, than reductions

Existing positions increased: 35 | Existing positions reduced: 40

14% less capital invested

Capital invested by funds: $119M → $103M (-$16.3M)

94% less call options, than puts

Call options by funds: $10K | Put options by funds: $157K

100% less funds holding in top 10

Funds holding in top 10: 1 → 0 (-1)

Holders
119
Holders Change
-1
Holders Change %
-0.83%
% of All Funds
1.45%
Holding in Top 10
–
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
–
New
15
Increased
35
Reduced
40
Closed
12
Calls
$10K
Puts
$157K
Net Calls
-$147K
Net Calls Change
-$4.11M

Top Buyers

1
MAM
Monaco Asset Management
Monaco
+$1.15M
2
Renaissance Technologies
Renaissance Technologies
New York
+$1.11M
3
Two Sigma Advisers
Two Sigma Advisers
New York
+$908K
4
Two Sigma Investments
Two Sigma Investments
New York
+$903K
5
BlackRock
BlackRock
New York
+$833K

Top Sellers

1
TCM
Tang Capital Management
California
-$11.1M
2
Citadel Advisors
Citadel Advisors
Florida
-$3.11M
3
Millennium Management
Millennium Management
New York
-$1.29M
4
Royal Bank of Canada
Royal Bank of Canada
Ontario, Canada
-$805K
5
Bank of America
Bank of America
North Carolina
-$665K
Name Holding Trade Value Shares
Change 		Change in
Stake
RCM
1
RA Capital Management
Massachusetts
$20M – – –
BlackRock
2
BlackRock
New York
$7.61M +$833K +416,601 +11%
NMC
3
NEA Management Company
Maryland
$6.6M – – –
SB
4
Samsara BioCapital
California
$6.49M -$520K -260,369 -7%
SOCM
5
SR One Capital Management
Pennsylvania
$6.17M – – –
GP
6
GSK plc
$5.83M +$6.3M +3,150,732 New
Vanguard Group
7
Vanguard Group
Pennsylvania
$4.81M +$211K +105,653 +4%
MAM
8
Monaco Asset Management
Monaco
$4.71M +$1.15M +576,022 +29%
Alyeska Investment Group
9
Alyeska Investment Group
Illinois
$3.86M +$288 +144 +0%
Renaissance Technologies
10
Renaissance Technologies
New York
$3.15M +$1.11M +556,945 +49%
WA
11
Wasatch Advisors
Utah
$2.92M -$123K -61,455 -4%
TCM
12
Tang Capital Management
California
$2.74M -$11.1M -5,574,753 -79%
Citadel Advisors
13
Citadel Advisors
Florida
$2.49M -$3.11M -1,554,525 -54%
State Street
14
State Street
Massachusetts
$2.16M +$42.5K +21,241 +2%
Geode Capital Management
15
Geode Capital Management
Massachusetts
$2.14M +$172K +86,218 +8%
Two Sigma Investments
16
Two Sigma Investments
New York
$1.8M +$903K +451,810 +87%
AIC
17
AWM Investment Company
New York
$1.68M +$212K +106,000 +13%
Blackstone Inc
18
Blackstone Inc
New York
$1.38M – – –
Acadian Asset Management
19
Acadian Asset Management
Massachusetts
$1.28M +$363K +181,391 +36%
PLC
20
Peapod Lane Capital
New York
$1.25M +$9.86K +4,933 +0.7%
Two Sigma Advisers
21
Two Sigma Advisers
New York
$1.2M +$908K +454,300 +236%
JP Morgan Chase
22
JP Morgan Chase
New York
$1.11M +$80.2K +40,145 +7%
Northern Trust
23
Northern Trust
Illinois
$665K -$34.6K -17,290 -5%
Goldman Sachs
24
Goldman Sachs
New York
$629K +$119K +59,458 +21%
AQR Capital Management
25
AQR Capital Management
Connecticut
$590K -$147K -73,573 -19%
1
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NKTX Hedge Fund Activity: Q4 2025 in Review

119 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Nkarta (NKTX) for Q4 2025, worth a combined $103M — down 14% from $119M a quarter earlier.

Buyers outnumbered sellers: 15 funds opened new NKTX positions and 12 closed out — a net gain of 3 holders — while 35 added to existing stakes and 40 trimmed.

The largest buyer was Monaco Asset Management, adding an estimated $1.15M. The largest seller was Tang Capital Management, cutting an estimated $11.1M.

  • 119 institutional investors held Nkarta (NKTX) as of Q4 2025, down from 120 in Q3 2025.
  • Funds reported $103M of Nkarta stock for Q4 2025, down 14% quarter-over-quarter.
  • 15 funds opened new Nkarta positions in Q4 2025 and 12 closed out, a net change of +3 holders.
  • The largest Nkarta buyer in Q4 2025 was Monaco Asset Management, an estimated $1.15M added.
  • The largest Nkarta seller in Q4 2025 was Tang Capital Management, an estimated $11.1M sold.

Based on aggregated 13F filings for Q4 2025.