NuCana
NCNA
9 hedge funds and large institutions have $643K invested in NuCana in 2025 Q4 according to their latest regulatory filings, with 1 funds opening new positions, 3 increasing their positions, 2 reducing their positions, and 2 closing their positions.
50% more repeat investments, than reductions
Existing positions increased: 3 | Existing positions reduced: 2
5.22% less ownership
Funds ownership: 593.39% → 588.17% (-5.2%)
10% less funds holding
Funds holding: 10 → 9 (-1)
23% less capital invested
Capital invested by funds: $836K → $643K (-$192K)
50% less first-time investments, than exits
New positions opened: 1 | Existing positions closed: 2
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
FIA
FNY Investment Advisers
New York
|
+$28K |
| 2 |
RhumbLine Advisers
Boston,
Massachusetts
|
+$18.3K |
| 3 |
Citigroup
New York
|
+$1.59K |
| 4 |
Morgan Stanley
New York
|
+$426 |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
UBS Group
Zurich,
Switzerland
|
-$27.3K |
| 2 |
GRP
Global Retirement Partners
San Rafael,
California
|
-$18.6K |
| 3 |
Jane Street
New York
|
-$5.93K |
| 4 |
TRCT
Tower Research Capital (TRC)
New York
|
-$5.7K |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
|
CG
1
Carlyle Group
Washington,
District of Columbia
| $480K | – | – | – |
|
|
GJIA
2
Glass Jacobson Investment Advisors
Owings Mills,
Maryland
| $54K | – | – | – |
|
|
3
Jane Street
New York
| $40.8K | -$5.93K | -1,433 | -11% |
|
|
FIA
4
FNY Investment Advisers
New York
| $36K | +$28K | +6,774 | +210% |
|
|
5
RhumbLine Advisers
Boston,
Massachusetts
| $17.7K | +$18.3K | +4,414 | +892% |
|
|
6
UBS Group
Zurich,
Switzerland
| $13.2K | -$27.3K | -6,598 | -64% |
|
|
7
Citigroup
New York
| $1.38K | +$1.59K | +383 | New |
|
|
8
Morgan Stanley
New York
| $378 | +$426 | +103 | +5,150% |
|
|
GRP
9
Global Retirement Partners
San Rafael,
California
| – | -$18.6K | -4,000 | Closed |
|
|
TRCT
10
Tower Research Capital (TRC)
New York
| – | -$5.7K | -1,229 | Closed |
|
NCNA Hedge Fund Activity: Q4 2025 in Review
9 of the 8,245 institutional investors tracked by Wall St. Rank reported a position in NuCana (NCNA) for Q4 2025, worth a combined $643K — down 23% from $836K a quarter earlier.
Sellers outnumbered buyers: 2 funds closed out of NCNA and 1 opened new positions — a net loss of 1 holder — while 2 trimmed existing stakes and 3 added.
The largest buyer was FNY Investment Advisers, adding an estimated $28K. The largest seller was UBS Group, cutting an estimated $27.3K.
- 9 institutional investors held NuCana (NCNA) as of Q4 2025, down from 10 in Q3 2025.
- Funds reported $643K of NuCana stock for Q4 2025, down 23% quarter-over-quarter.
- 1 fund opened new NuCana positions in Q4 2025 and 2 closed out, a net change of -1 holder.
- The largest NuCana buyer in Q4 2025 was FNY Investment Advisers, an estimated $28K added.
- The largest NuCana seller in Q4 2025 was UBS Group, an estimated $27.3K sold.
Based on aggregated 13F filings for Q4 2025.