|
1
|
Bellevue Group
Kuesnacht,
Switzerland
|
$103M
|
+$20.3M
|
+115,718
|
+27%
|
|
|
2
|
|
$38.6M
|
-$199K
|
-1,133
|
-0.6%
|
|
|
3
|
BVF Inc
San Francisco,
California
|
$36.1M
|
+$8.36M
|
+47,683
|
+33%
|
|
|
4
|
Pictet Asset Management (UK)
London,
United Kingdom
|
$33.6M
|
+$3.51M
|
+20,000
|
+13%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$32.5M
|
+$2.29M
|
+13,032
|
+8%
|
|
|
6
|
Caxton Corporation
Princeton,
New Jersey
|
$26.8M
|
–
|
–
|
–
|
|
|
7
|
Frazier Management
Seattle,
Washington
|
$17.3M
|
+$6.22M
|
+35,476
|
+63%
|
|
|
8
|
Woodline Partners
San Francisco,
California
|
$14.5M
|
+$7.34M
|
+41,857
|
+121%
|
|
|
9
|
Kingdon Capital Management
New York
|
$12.1M
|
+$2.34M
|
+13,334
|
+26%
|
|
|
10
|
Adage Capital Partners
Boston,
Massachusetts
|
$11.9M
|
+$11M
|
+62,667
|
New
|
|
|
11
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$10.7M
|
+$9.53M
|
+54,375
|
+2,684%
|
|
|
12
|
Millennium Management
New York
|
$9.04M
|
+$3.15M
|
+17,978
|
+60%
|
|
|
13
|
Endurant Capital Management
San Mateo,
California
|
$8.95M
|
+$329K
|
+1,875
|
+4%
|
|
|
14
|
Fidelity Investments
Boston,
Massachusetts
|
$7.88M
|
+$4.62M
|
+26,350
|
+173%
|
|
|
15
|
Sectoral Asset Management
Montreal,
Quebec, Canada
|
$7.78M
|
+$4.58M
|
+26,130
|
+175%
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$7.12M
|
+$864K
|
+4,925
|
+15%
|
|
|
17
|
State Street
Boston,
Massachusetts
|
$5.74M
|
-$46.3K
|
-264
|
-0.9%
|
|
|
18
|
Northern Trust
Chicago,
Illinois
|
$4.64M
|
-$269K
|
-1,533
|
-6%
|
|
|
19
|
SVB Wealth
Boston,
Massachusetts
|
$4.35M
|
+$525K
|
+2,994
|
+15%
|
|
|
20
|
|
$4.17M
|
+$2.83M
|
+16,154
|
+276%
|
|
|
21
|
Two Sigma Advisers
New York
|
$4.02M
|
-$616K
|
-3,513
|
-14%
|
|
|
22
|
Dimensional Fund Advisors
Austin,
Texas
|
$3.63M
|
-$46.1K
|
-263
|
-1%
|
|
|
23
|
Charles Schwab
San Francisco,
California
|
$3.08M
|
+$310K
|
+1,769
|
+12%
|
|
|
24
|
AJU IB Investment Company
Seoul,
South Korea
|
$2.58M
|
–
|
–
|
–
|
|
|
25
|
Tekla Capital Management
Boston,
Massachusetts
|
$2.52M
|
-$238K
|
-1,360
|
-9%
|
|
