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3,660 hedge funds and large institutions have $207B invested in Merck in 2025 Q4 according to their latest regulatory filings, with 549 funds opening new positions, 1,376 increasing their positions, 1,400 reducing their positions, and 131 closing their positions.

New
Increased
Maintained
Reduced
Closed

319% more first-time investments, than exits

New positions opened: 549 | Existing positions closed: 131

67% more funds holding in top 10

Funds holding in top 10: 4677 (+31)

43% more call options, than puts

Call options by funds: $3.76B | Put options by funds: $2.62B

30% more capital invested

Capital invested by funds: $160B → $207B (+$47.2B)

10% more funds holding

Funds holding: 3,3133,660 (+347)

2.9% more ownership

Funds ownership: 76.23%79.13% (+2.9%)

2% less repeat investments, than reductions

Existing positions increased: 1,376 | Existing positions reduced: 1,400

Holders
3,660
Holders Change
+347
Holders Change %
+10.47%
% of All Funds
44.33%
Holding in Top 10
77
Holding in Top 10 Change
+31
Holding in Top 10 Change %
+67.39%
% of All Funds
0.93%
New
549
Increased
1,376
Reduced
1,400
Closed
131
Calls
$3.76B
Puts
$2.62B
Net Calls
+$1.14B
Net Calls Change
+$810M

MRK Hedge Fund Activity: Q4 2025 in Review

3,660 of the 8,257 institutional investors tracked by Wall St. Rank reported a position in Merck (MRK) for Q4 2025, worth a combined $207B — up 30% from $160B a quarter earlier.

Buyers outnumbered sellers: 549 funds opened new MRK positions and 131 closed out — a net gain of 418 holders — while 1,376 added to existing stakes and 1,400 trimmed.

The largest buyer was Wellington Management Group, adding an estimated $1.05B. The largest seller was Arrowstreet Capital, cutting an estimated $823M.

  • 3,660 institutional investors held Merck (MRK) as of Q4 2025, up from 3,313 in Q3 2025.
  • Funds reported $207B of Merck stock for Q4 2025, up 30% quarter-over-quarter.
  • 549 funds opened new Merck positions in Q4 2025 and 131 closed out, a net change of +418 holders.
  • The largest Merck buyer in Q4 2025 was Wellington Management Group, an estimated $1.05B added.
  • The largest Merck seller in Q4 2025 was Arrowstreet Capital, an estimated $823M sold.

Based on aggregated 13F filings for Q4 2025.