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Mineralys Therapeutics

165 hedge funds and large institutions have $889M invested in Mineralys Therapeutics in 2025 Q2 according to their latest regulatory filings, with 41 funds opening new positions, 76 increasing their positions, 30 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed

153% more repeat investments, than reductions

Existing positions increased: 76 | Existing positions reduced: 30

71% more first-time investments, than exits

New positions opened: 41 | Existing positions closed: 24

11% more funds holding

Funds holding: 149165 (+16)

3.37% more ownership

Funds ownership: 97.42%100.79% (+3.4%)

9% less capital invested

Capital invested by funds: $971M → $889M (-$82.6M)

10% less funds holding in top 10

Funds holding in top 10: 109 (-1)

97% less call options, than puts

Call options by funds: $30K | Put options by funds: $1.11M

Holders
165
Holders Change
+16
Holders Change %
+10.74%
% of All Funds
2.17%
Holding in Top 10
9
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-10%
% of All Funds
0.12%
New
41
Increased
76
Reduced
30
Closed
24
Calls
$30K
Puts
$1.11M
Net Calls
-$1.08M
Net Calls Change
+$2.81M
Name Holding Trade Value Shares
Change
Change in
Stake
Federated Hermes
101
Federated Hermes
Pennsylvania
$224K +$66.3K +4,577 +38%
LBA
102
Letko, Brosseau & Associates
Quebec, Canada
$223K
FRM
103
Fox Run Management
Connecticut
$220K +$235K +16,243 New
CCM
104
Cinctive Capital Management
New York
$218K +$27.4K +1,894 +13%
BG
105
Bellevue Group
Switzerland
$210K -$13.7K -943 -6%
SO
106
STRS Ohio
Ohio
$208K -$104K -7,200 -32%
A
107
AlphaQuest
New York
$201K -$15.7K -1,084 -7%
Manulife (Manufacturers Life Insurance)
108
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$200K +$49.1K +3,390 +30%
Citadel Advisors
109
Citadel Advisors
Florida
$195K -$1.88M -129,980 -90%
QCM
110
Quantinno Capital Management
New York
$184K +$12.4K +859 +7%
CUAMC
111
China Universal Asset Management Company
China
$177K +$44.8K +3,094 +31%
Allianz Asset Management
112
Allianz Asset Management
Germany
$166K +$178K +12,300 New
PA
113
Profund Advisors
Maryland
$164K +$176K +12,131 New
QC
114
Quadrature Capital
United Kingdom
$162K -$884K -61,021 -84%
Janus Henderson Group
115
Janus Henderson Group
United Kingdom
$157K +$168K +11,600 New
Squarepoint
116
Squarepoint
New York
$156K +$167K +11,515 New
CW
117
CreativeOne Wealth
Kansas
$145K
ProShare Advisors
118
ProShare Advisors
Maryland
$141K +$152K +10,457 New
Group One Trading
119
Group One Trading
Illinois
$137K -$37.2K -2,567 -20%
HF
120
HRT Financial
New York
$136K +$146K +10,077 New
GCM
121
Greenland Capital Management
New York
$135K -$145K -10,000 -50%
Royal Bank of Canada
122
Royal Bank of Canada
Ontario, Canada
$130K +$120K +8,264 +636%
PFSRSONJ
123
Police & Firemen's Retirement System of New Jersey
New Jersey
$125K +$30.4K +2,098 +29%
New York State Common Retirement Fund
124
New York State Common Retirement Fund
New York
$105K
KK
125
KLP Kapitalforvaltning
Norway
$90.7K +$97.1K +6,700 New

MLYS Hedge Fund Activity: Q2 2025 in Review

165 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Mineralys Therapeutics (MLYS) for Q2 2025, worth a combined $889M — down 8.5% from $971M a quarter earlier.

Buyers outnumbered sellers: 41 funds opened new MLYS positions and 24 closed out — a net gain of 17 holders — while 76 added to existing stakes and 30 trimmed.

The largest buyer was Capital International Investors, opening a new position worth an estimated $42M. The largest seller was TCG Crossover Management, exiting entirely with an estimated $39.2M sold.

  • 165 institutional investors held Mineralys Therapeutics (MLYS) as of Q2 2025, up from 149 in Q1 2025.
  • Funds reported $889M of Mineralys Therapeutics stock for Q2 2025, down 8.5% quarter-over-quarter.
  • 41 funds opened new Mineralys Therapeutics positions in Q2 2025 and 24 closed out, a net change of +17 holders.
  • The largest Mineralys Therapeutics buyer in Q2 2025 was Capital International Investors, an estimated $42M added.
  • The largest Mineralys Therapeutics seller in Q2 2025 was TCG Crossover Management, an estimated $39.2M sold.

Based on aggregated 13F filings for Q2 2025.