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Mineralys Therapeutics

165 hedge funds and large institutions have $889M invested in Mineralys Therapeutics in 2025 Q2 according to their latest regulatory filings, with 41 funds opening new positions, 76 increasing their positions, 30 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed

153% more repeat investments, than reductions

Existing positions increased: 76 | Existing positions reduced: 30

71% more first-time investments, than exits

New positions opened: 41 | Existing positions closed: 24

11% more funds holding

Funds holding: 149165 (+16)

3.37% more ownership

Funds ownership: 97.42%100.79% (+3.4%)

9% less capital invested

Capital invested by funds: $971M → $889M (-$82.6M)

10% less funds holding in top 10

Funds holding in top 10: 109 (-1)

97% less call options, than puts

Call options by funds: $30K | Put options by funds: $1.11M

Holders
165
Holders Change
+16
Holders Change %
+10.74%
% of All Funds
2.17%
Holding in Top 10
9
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-10%
% of All Funds
0.12%
New
41
Increased
76
Reduced
30
Closed
24
Calls
$30K
Puts
$1.11M
Net Calls
-$1.08M
Net Calls Change
+$2.81M
Name Holding Trade Value Shares
Change
Change in
Stake
Renaissance Technologies
51
Renaissance Technologies
New York
$2.39M -$5.42K -374 -0.2%
VCIM
52
Velan Capital Investment Management
Georgia
$2.36M +$348K +24,000 +16%
ECM
53
ExodusPoint Capital Management
New York
$2.33M +$2.5M +172,552 New
ZP
54
Zimmer Partners
New York
$2.2M +$2.36M +162,733 New
SPS
55
Susquehanna Portfolio Strategies
Pennsylvania
$2.18M +$2.07M +142,889 +783%
HS
56
HighVista Strategies
Massachusetts
$2.03M +$2.18M +150,138 New
Barclays
57
Barclays
United Kingdom
$1.95M +$1.61M +110,984 +337%
DFCM
58
Dark Forest Capital Management
Puerto Rico
$1.71M +$1.55M +106,721 +533%
SG Americas Securities
59
SG Americas Securities
New York
$1.68M +$1.65M +113,530 +1,086%
Wellington Management Group
60
Wellington Management Group
Massachusetts
$1.56M -$88.5K -6,109 -5%
SCM
61
Silverarc Capital Management
Massachusetts
$1.56M -$3.23M -223,072 -66%
UBS Group
62
UBS Group
Switzerland
$1.56M +$1.13M +77,978 +210%
Ensign Peak Advisors
63
Ensign Peak Advisors
Utah
$1.46M +$1.02M +70,147 +187%
Bank of New York Mellon
64
Bank of New York Mellon
New York
$1.3M +$414K +28,547 +42%
WP
65
Woodline Partners
California
$1.19M +$583K +40,206 +84%
UOC
66
UBS O'Connor
Illinois
$1.08M +$92.4K +6,375 +9%
LPC
67
Lion Point Capital
New York
$1.07M
N
68
Nuveen
North Carolina
$1.05M +$142K +9,770 +14%
Walleye Capital
69
Walleye Capital
New York
$1M +$1.07M +73,921 New
Swiss National Bank
70
Swiss National Bank
Switzerland
$838K +$897K +61,900 New
JGC
71
J. Goldman & Co
New York
$780K -$1.75M -120,669 -68%
Rafferty Asset Management
72
Rafferty Asset Management
New York
$776K +$831K +57,375 New
Susquehanna International Group
73
Susquehanna International Group
Pennsylvania
$759K -$87.8K -6,058 -10%
RhumbLine Advisers
74
RhumbLine Advisers
Massachusetts
$725K +$206K +14,235 +36%
Ameriprise
75
Ameriprise
Minnesota
$688K +$737K +50,857 New

MLYS Hedge Fund Activity: Q2 2025 in Review

165 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Mineralys Therapeutics (MLYS) for Q2 2025, worth a combined $889M — down 8.5% from $971M a quarter earlier.

Buyers outnumbered sellers: 41 funds opened new MLYS positions and 24 closed out — a net gain of 17 holders — while 76 added to existing stakes and 30 trimmed.

The largest buyer was Capital International Investors, opening a new position worth an estimated $42M. The largest seller was TCG Crossover Management, exiting entirely with an estimated $39.2M sold.

  • 165 institutional investors held Mineralys Therapeutics (MLYS) as of Q2 2025, up from 149 in Q1 2025.
  • Funds reported $889M of Mineralys Therapeutics stock for Q2 2025, down 8.5% quarter-over-quarter.
  • 41 funds opened new Mineralys Therapeutics positions in Q2 2025 and 24 closed out, a net change of +17 holders.
  • The largest Mineralys Therapeutics buyer in Q2 2025 was Capital International Investors, an estimated $42M added.
  • The largest Mineralys Therapeutics seller in Q2 2025 was TCG Crossover Management, an estimated $39.2M sold.

Based on aggregated 13F filings for Q2 2025.