|
1
|
Flagship Pioneering
Cambridge,
Massachusetts
|
$611M
|
–
|
–
|
–
|
|
|
2
|
ARK Investment Management
St. Petersburg,
Florida
|
$348M
|
-$3.09M
|
-9,295
|
-1%
|
|
|
3
|
Fidelity Investments
Boston,
Massachusetts
|
$303M
|
+$82.7M
|
+248,766
|
+87%
|
|
|
4
|
|
$170M
|
+$24.7M
|
+74,400
|
+33%
|
|
|
5
|
Sumitomo Mitsui Trust Group
Minato-Ku, Tokyo,
Japan
|
$157M
|
-$31.1M
|
-93,428
|
-25%
|
|
|
6
|
Nikko Asset Management Americas
New York
|
$152M
|
-$31.1M
|
-93,428
|
-25%
|
|
|
7
|
RA Capital Management
Boston,
Massachusetts
|
$134M
|
+$79M
|
+237,500
|
New
|
|
|
8
|
Gilder Gagnon Howe & Co
New York
|
$90.2M
|
+$51.2M
|
+154,093
|
+2,976%
|
|
|
9
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$79M
|
+$29.3M
|
+88,043
|
+171%
|
|
|
10
|
Vanguard Group
Malvern,
Pennsylvania
|
$78M
|
+$8.27M
|
+24,868
|
+22%
|
|
|
11
|
Janus Henderson Group
London,
|
$54.2M
|
+$31.8M
|
+95,704
|
New
|
|
|
12
|
State Street
Boston,
Massachusetts
|
$26M
|
+$1.7M
|
+5,127
|
+13%
|
|
|
13
|
Geode Capital Management
Boston,
Massachusetts
|
$22.6M
|
+$1.01M
|
+3,051
|
+8%
|
|
|
14
|
Northern Trust
Chicago,
Illinois
|
$18.5M
|
+$1.66M
|
+5,003
|
+18%
|
|
|
15
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$16.5M
|
+$9.24M
|
+27,799
|
+2,124%
|
|
|
16
|
|
$14.1M
|
-$5.27M
|
-15,861
|
-39%
|
|
|
17
|
Renaissance Technologies
New York
|
$10.7M
|
-$16.9M
|
-50,825
|
-73%
|
|
|
18
|
Charles Schwab
San Francisco,
California
|
$9.7M
|
-$1.22M
|
-3,659
|
-18%
|
|
|
19
|
Opaleye Management
Boston,
Massachusetts
|
$9.49M
|
+$5.58M
|
+16,766
|
New
|
|
|
20
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$9.09M
|
+$5.34M
|
+16,047
|
New
|
|
|
21
|
|
$8.49M
|
+$4.99M
|
+15,000
|
New
|
|
|
22
|
Millennium Management
New York
|
$7.98M
|
-$1.47M
|
-4,419
|
-24%
|
|
|
23
|
Bank of New York Mellon
New York
|
$5.32M
|
+$917K
|
+2,758
|
+42%
|
|
|
24
|
|
$5.04M
|
-$12.1M
|
-36,284
|
-81%
|
|
|
25
|
Point72 Asset Management
Stamford,
Connecticut
|
$4.71M
|
+$2.77M
|
+8,319
|
New
|
|
