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Seres Therapeutics

32 hedge funds and large institutions have $40.9M invested in Seres Therapeutics in 2025 Q3 according to their latest regulatory filings, with 9 funds opening new positions, 10 increasing their positions, 7 reducing their positions, and 10 closing their positions.

New
Increased
Maintained
Reduced
Closed

571% more call options, than puts

Call options by funds: $17.4M | Put options by funds: $2.6M

61% more capital invested

Capital invested by funds: $25.4M → $40.9M (+$15.5M)

43% more repeat investments, than reductions

Existing positions increased: 10 | Existing positions reduced: 7

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

1.88% less ownership

Funds ownership: 26.17%24.28% (-1.9%)

3% less funds holding

Funds holding: 3332 (-1)

10% less first-time investments, than exits

New positions opened: 9 | Existing positions closed: 10

Holders
32
Holders Change
-1
Holders Change %
-3.03%
% of All Funds
0.42%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
9
Increased
10
Reduced
7
Closed
10
Calls
$17.4M
Puts
$2.6M
Net Calls
+$14.8M
Net Calls Change
+$12.9M
Name Holding Trade Value Shares
Change
Change in
Stake
FP
1
Flagship Pioneering
Massachusetts
$22.2M
Vanguard Group
2
Vanguard Group
Pennsylvania
$6M +$316K +19,793 +7%
Marshall Wace
3
Marshall Wace
United Kingdom
$2.42M +$546K +34,195 +37%
BlackRock
4
BlackRock
New York
$1.96M +$11.3K +709 +0.7%
Vontobel Holding
5
Vontobel Holding
Switzerland
$1.9M +$290K +18,186 +23%
Geode Capital Management
6
Geode Capital Management
Massachusetts
$1.64M -$106K -6,620 -7%
Charles Schwab
7
Charles Schwab
California
$604K -$55.4K -3,473 -10%
Citadel Advisors
8
Citadel Advisors
Florida
$594K +$493K +30,885 New
State Street
9
State Street
Massachusetts
$572K +$46.3K +2,900 +11%
SSA
10
Schonfeld Strategic Advisors
New York
$557K +$462K +28,942 New
LPC
11
Lion Point Capital
New York
$522K +$161K +10,100 +59%
JGC
12
J. Goldman & Co
New York
$519K +$431K +27,000 New
Morgan Stanley
13
Morgan Stanley
New York
$353K +$167K +10,496 +134%
UBS Group
14
UBS Group
Switzerland
$244K +$82.2K +5,150 +68%
Northern Trust
15
Northern Trust
Illinois
$233K -$47.5K -2,975 -20%
Invesco
16
Invesco
Georgia
$201K +$167K +10,442 New
Bank of America
17
Bank of America
North Carolina
$103K +$82.3K +5,157 +2,773%
SS
18
SBI Securities
Japan
$67K
Simplex Trading
19
Simplex Trading
Illinois
$54K +$44.8K +2,807 New
Citigroup
20
Citigroup
New York
$50.4K +$41.7K +2,612 +29,022%
Fidelity Investments
21
Fidelity Investments
Massachusetts
$36.2K -$4.26M -266,822 -99%
Barclays
22
Barclays
United Kingdom
$27.1K +$22.5K +1,408 New
Royal Bank of Canada
23
Royal Bank of Canada
Ontario, Canada
$6K -$106K -6,658 -96%
BNP Paribas Financial Markets
24
BNP Paribas Financial Markets
France
$4.08K -$1.48K -93 -30%
PWA
25
Physician Wealth Advisors
Utah
$2.73K

MCRB Hedge Fund Activity: Q3 2025 in Review

32 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Seres Therapeutics (MCRB) for Q3 2025, worth a combined $40.9M — up 61% from $25.4M a quarter earlier.

Sellers outnumbered buyers: 10 funds closed out of MCRB and 9 opened new positions — a net loss of 1 holder — while 7 trimmed existing stakes and 10 added.

The largest buyer was Marshall Wace, adding an estimated $546K. The largest seller was Fidelity Investments, cutting an estimated $4.26M.

  • 32 institutional investors held Seres Therapeutics (MCRB) as of Q3 2025, down from 33 in Q2 2025.
  • Funds reported $40.9M of Seres Therapeutics stock for Q3 2025, up 61% quarter-over-quarter.
  • 9 funds opened new Seres Therapeutics positions in Q3 2025 and 10 closed out, a net change of -1 holder.
  • The largest Seres Therapeutics buyer in Q3 2025 was Marshall Wace, an estimated $546K added.
  • The largest Seres Therapeutics seller in Q3 2025 was Fidelity Investments, an estimated $4.26M sold.

Based on aggregated 13F filings for Q3 2025.