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Seres Therapeutics
MCRB

32 hedge funds and large institutions have $40.9M invested in Seres Therapeutics in 2025 Q3 according to their latest regulatory filings, with 9 funds opening new positions, 10 increasing their positions, 7 reducing their positions, and 10 closing their positions.

New
Increased
Maintained
Reduced
Closed

571% more call options, than puts

Call options by funds: $17.4M | Put options by funds: $2.6M

61% more capital invested

Capital invested by funds: $25.4M → $40.9M (+$15.5M)

43% more repeat investments, than reductions

Existing positions increased: 10 | Existing positions reduced: 7

0% more funds holding in top 10

Funds holding in top 10: 1 → 1 (0)

1.88% less ownership

Funds ownership: 26.17% → 24.28% (-1.9%)

3% less funds holding

Funds holding: 33 → 32 (-1)

10% less first-time investments, than exits

New positions opened: 9 | Existing positions closed: 10

Holders
32
Holders Change
-1
Holders Change %
-3.03%
% of All Funds
0.42%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
9
Increased
10
Reduced
7
Closed
10
Calls
$17.4M
Puts
$2.6M
Net Calls
+$14.8M
Net Calls Change
+$12.9M

Top Buyers

Rank Fund Capital Flow
1
Marshall Wace
Marshall Wace
United Kingdom
+$546K
2
Citadel Advisors
Citadel Advisors
Florida
+$493K
3
SSA
Schonfeld Strategic Advisors
New York
+$462K
4
JGC
J. Goldman & Co
New York
+$431K
5
Vanguard Group
Vanguard Group
Pennsylvania
+$316K

Top Sellers

Rank Fund Capital Flow
1
Fidelity Investments
Fidelity Investments
Massachusetts
-$4.26M
2
XT
XTX Topco
Cayman Islands
-$249K
3
Squarepoint
Squarepoint
New York
-$232K
4
Susquehanna International Group
Susquehanna International Group
Pennsylvania
-$186K
5
TCM
Tang Capital Management
California
-$155K
Name Holding Trade Value Shares
Change 		Change in
Stake
JP Morgan Chase
26
JP Morgan Chase
New York
$1.25K – – –
US Bancorp
27
US Bancorp
Minnesota
$231 -$207 -13 -52%
Wells Fargo
28
Wells Fargo
California
$192 – – –
SIS
29
Sound Income Strategies
Florida
$156 +$128 +8 New
Osaic Holdings
30
Osaic Holdings
Arizona
$151 – – –
FDCDDQ
31
Federation des caisses Desjardins du Quebec
Quebec, Canada
$58 +$48 +3 New
AAP
32
Arax Advisory Partners
Colorado
$38 +$32 +2 New
XT
33
XTX Topco
Cayman Islands
– -$249K -22,417 Closed
Squarepoint
34
Squarepoint
New York
– -$232K -20,908 Closed
TCM
35
Tang Capital Management
California
– -$155K -13,921 Closed
BCM
36
Bridgeway Capital Management
Texas
– -$139K -12,500 Closed
Susquehanna International Group
37
Susquehanna International Group
Pennsylvania
– -$186K -11,684 Closed
Group One Trading
38
Group One Trading
Illinois
– -$18.5K -1,161 Closed
AUB
39
Atlantic Union Bankshares
Virginia
– -$4.57K -411 Closed
TRCT
40
Tower Research Capital (TRC)
New York
– -$2.06K -185 Closed
Raymond James Financial
41
Raymond James Financial
Florida
– -$623 -56 Closed
WT
42
Whittier Trust
California
– -$11 -1 Closed
1
2

MCRB Hedge Fund Activity: Q3 2025 in Review

32 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Seres Therapeutics (MCRB) for Q3 2025, worth a combined $40.9M — up 61% from $25.4M a quarter earlier.

Sellers outnumbered buyers: 10 funds closed out of MCRB and 9 opened new positions — a net loss of 1 holder — while 7 trimmed existing stakes and 10 added.

The largest buyer was Marshall Wace, adding an estimated $546K. The largest seller was Fidelity Investments, cutting an estimated $4.26M.

  • 32 institutional investors held Seres Therapeutics (MCRB) as of Q3 2025, down from 33 in Q2 2025.
  • Funds reported $40.9M of Seres Therapeutics stock for Q3 2025, up 61% quarter-over-quarter.
  • 9 funds opened new Seres Therapeutics positions in Q3 2025 and 10 closed out, a net change of -1 holder.
  • The largest Seres Therapeutics buyer in Q3 2025 was Marshall Wace, an estimated $546K added.
  • The largest Seres Therapeutics seller in Q3 2025 was Fidelity Investments, an estimated $4.26M sold.

Based on aggregated 13F filings for Q3 2025.