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Mustang Bio
MBIO

25 hedge funds and large institutions have $542K invested in Mustang Bio in 2025 Q4 according to their latest regulatory filings, with 7 funds opening new positions, 6 increasing their positions, 3 reducing their positions, and 2 closing their positions.

New
Increased
Maintained
Reduced
Closed

250% more first-time investments, than exits

New positions opened: 7 | Existing positions closed: 2

100% more repeat investments, than reductions

Existing positions increased: 6 | Existing positions reduced: 3

27% more capital invested

Capital invested by funds: $427K → $542K (+$115K)

25% more funds holding

Funds holding: 20 → 25 (+5)

4.16% more ownership

Funds ownership: 4.39% → 8.55% (+4.2%)

Holders
25
Holders Change
+5
Holders Change %
+25%
% of All Funds
0.3%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
7
Increased
6
Reduced
3
Closed
2
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

Rank Fund Capital Flow
1
Citadel Advisors
Citadel Advisors
Florida
+$112K
2
DS
DRW Securities
Illinois
+$97.6K
3
KAS
Kestra Advisory Services
Texas
+$59.3K
4
Two Sigma Investments
Two Sigma Investments
New York
+$52.9K
5
Jane Street
Jane Street
New York
+$18.6K

Top Sellers

Rank Fund Capital Flow
1
Renaissance Technologies
Renaissance Technologies
New York
-$17.9K
2
Citigroup
Citigroup
New York
-$915
3
TRCT
Tower Research Capital (TRC)
New York
-$523
4
Morgan Stanley
Morgan Stanley
New York
-$198
5
UBS Group
UBS Group
Switzerland
-$5
Name Holding Trade Value Shares
Change 		Change in
Stake
KAS
1
Kestra Advisory Services
Texas
$109K +$59.3K +44,934 +68%
Citadel Advisors
2
Citadel Advisors
Florida
$83.2K +$112K +84,765 New
BlackRock
3
BlackRock
New York
$83.1K – – –
DS
4
DRW Securities
Illinois
$72.5K +$97.6K +73,936 New
Vanguard Group
5
Vanguard Group
Pennsylvania
$56.8K – – –
Two Sigma Investments
6
Two Sigma Investments
New York
$39.3K +$52.9K +40,034 New
Geode Capital Management
7
Geode Capital Management
Massachusetts
$31.7K +$7.75K +5,867 +22%
XT
8
XTX Topco
Cayman Islands
$23.6K +$6.99K +5,298 +28%
Jane Street
9
Jane Street
New York
$13.9K +$18.6K +14,126 New
GCP
10
GSA Capital Partners
United Kingdom
$13K +$16.9K +12,834 New
CG
11
CFO4Life Group
Texas
$12.7K +$3.3K +2,500 +24%
SS
12
SBI Securities
Japan
$1.97K +$3 +2 +0.1%
TRCT
13
Tower Research Capital (TRC)
New York
$918 -$523 -396 -30%
Morgan Stanley
14
Morgan Stanley
New York
$150 -$198 -150 -50%
HI
15
Harbour Investments
Wisconsin
$75 – – –
Bank of America
16
Bank of America
North Carolina
$53 +$3 +2 +4%
UBS Group
17
UBS Group
Switzerland
$43 -$5 -4 -8%
CFB
18
Cullen/Frost Bankers
Texas
$13 +$17 +13 New
BNP Paribas Financial Markets
19
BNP Paribas Financial Markets
France
$6 – – –
MCM
20
MAI Capital Management
Ohio
$3 +$4 +3 New
DB
21
Danske Bank
Denmark
$2 – – –
JP Morgan Chase
22
JP Morgan Chase
New York
$2 – – –
NS
23
NBC Securities
Alabama
$2 – – –
Group One Trading
24
Group One Trading
Illinois
$1 – – –
Renaissance Technologies
25
Renaissance Technologies
New York
– -$17.9K -11,800 Closed
1
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MBIO Hedge Fund Activity: Q4 2025 in Review

25 of the 8,229 institutional investors tracked by Wall St. Rank reported a position in Mustang Bio (MBIO) for Q4 2025, worth a combined $542K — up 27% from $427K a quarter earlier.

Buyers outnumbered sellers: 7 funds opened new MBIO positions and 2 closed out — a net gain of 5 holders — while 6 added to existing stakes and 3 trimmed.

The largest buyer was Citadel Advisors, opening a new position worth an estimated $112K. The largest seller was Renaissance Technologies, exiting entirely with an estimated $17.9K sold.

  • 25 institutional investors held Mustang Bio (MBIO) as of Q4 2025, up from 20 in Q3 2025.
  • Funds reported $542K of Mustang Bio stock for Q4 2025, up 27% quarter-over-quarter.
  • 7 funds opened new Mustang Bio positions in Q4 2025 and 2 closed out, a net change of +5 holders.
  • The largest Mustang Bio buyer in Q4 2025 was Citadel Advisors, an estimated $112K added.
  • The largest Mustang Bio seller in Q4 2025 was Renaissance Technologies, an estimated $17.9K sold.

Based on aggregated 13F filings for Q4 2025.