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MASS

Name Holding Trade Value Shares
Change 		Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$42.6M +$43.7M +748,566 New
TCM
2
Tao Capital Management
California
$40.7M +$41.8M +715,519 New
T. Rowe Price Associates
3
T. Rowe Price Associates
Maryland
$32.6M +$33.5M +573,000 New
CAM
4
Cormorant Asset Management
Massachusetts
$29.5M +$31.9M +545,322 New
AIM
5
ARK Investment Management
Florida
$24.9M +$25.5M +437,248 New
Capital World Investors
6
Capital World Investors
California
$24.2M +$24.8M +425,000 New
CC
7
Casdin Capital
New York
$23.1M +$23.7M +406,502 New
Sands Capital Management
8
Sands Capital Management
Virginia
$22.4M +$23M +393,128 New
EAM
9
Eventide Asset Management
Massachusetts
$19M +$19.5M +333,283 New
Primecap Management
10
Primecap Management
California
$18.5M +$19M +325,000 New
BlackRock
11
BlackRock
New York
$17.1M +$17.5M +300,000 New
Wellington Management Group
12
Wellington Management Group
Massachusetts
$17.1M +$17.5M +299,969 New
Ameriprise
13
Ameriprise
Minnesota
$16.6M +$17.1M +292,115 New
Millennium Management
14
Millennium Management
New York
$12.2M +$12.5M +214,154 New
Lord, Abbett & Co
15
Lord, Abbett & Co
New Jersey
$8.57M +$8.79M +150,525 New
Adage Capital Partners
16
Adage Capital Partners
Massachusetts
$8.54M +$8.76M +150,000 New
PVI
17
Pura Vida Investments
New York
$7.97M +$8.18M +140,000 New
Invesco
18
Invesco
Georgia
$6.55M +$6.72M +115,000 New
NIP
19
Nicholas Investment Partners
California
$5.33M +$5.47M +93,595 New
Janus Henderson Group
20
Janus Henderson Group
$4.79M +$4.92M +84,190 New
Federated Hermes
21
Federated Hermes
Pennsylvania
$4.56M +$4.67M +80,000 New
FLAM
22
First Light Asset Management
Minnesota
$4.56M +$4.67M +80,000 New
PA
23
Perceptive Advisors
New York
$4.41M +$4.53M +77,500 New
DM
24
Deerfield Management
New York
$4.27M +$4.38M +75,000 New
FCM
25
Farallon Capital Management
California
$4.27M +$4.38M +75,000 New
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