|
1
|
|
$108M
|
+$9.23M
|
+343,869
|
+10%
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$83.5M
|
+$72.6M
|
+2,704,079
|
+1,174%
|
|
|
3
|
|
$61.9M
|
–
|
–
|
–
|
|
|
4
|
NEA Management Company
Timonium,
Maryland
|
$51M
|
–
|
–
|
–
|
|
|
5
|
RS Investment Management
San Francisco,
California
|
$41.1M
|
-$2.81M
|
-104,674
|
-7%
|
|
|
6
|
BVF Inc
San Francisco,
California
|
$20.2M
|
-$22M
|
-820,041
|
-54%
|
|
|
7
|
Eventide Asset Management
Boston,
Massachusetts
|
$15.7M
|
+$5.75M
|
+214,100
|
+63%
|
|
|
8
|
Adage Capital Partners
Boston,
Massachusetts
|
$14.2M
|
+$13.4M
|
+500,000
|
New
|
|
|
9
|
Visium Asset Management
New York
|
$11.4M
|
–
|
–
|
–
|
|
|
10
|
Driehaus Capital Management
Chicago,
Illinois
|
$10M
|
-$2.34M
|
-87,328
|
-20%
|
|
|
11
|
|
$7.84M
|
-$308K
|
-11,470
|
-4%
|
|
|
12
|
Vanguard Group
Malvern,
Pennsylvania
|
$7.19M
|
+$2.56M
|
+95,426
|
+61%
|
|
|
13
|
|
$7.16M
|
+$6.75M
|
+251,500
|
New
|
|
|
14
|
Deerfield Management
New York
|
$7.14M
|
-$22.5M
|
-837,225
|
-77%
|
|
|
15
|
BlackRock Fund Advisors
San Francisco,
California
|
$6.76M
|
+$1.15M
|
+42,918
|
+22%
|
|
|
16
|
Baker Bros. Advisors
New York
|
$3.92M
|
+$1.01M
|
+37,735
|
+38%
|
|
|
17
|
BlackRock Institutional Trust
San Francisco,
California
|
$3.61M
|
+$211K
|
+7,849
|
+7%
|
|
|
18
|
State Street
Boston,
Massachusetts
|
$3.53M
|
+$1.92M
|
+71,427
|
+136%
|
|
|
19
|
EAM Investors
Solana Beach,
California
|
$3.13M
|
-$341K
|
-12,697
|
-10%
|
|
|
20
|
AWM Investment Company
New York
|
$2.99M
|
+$805K
|
+30,000
|
+40%
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
$2.55M
|
+$578K
|
+21,528
|
+32%
|
|
|
22
|
|
$2.39M
|
+$88.5K
|
+3,298
|
+4%
|
|
|
23
|
|
$2.34M
|
+$2.21M
|
+82,179
|
New
|
|
|
24
|
DAFNA Capital Management
Los Angeles,
California
|
$1.76M
|
+$1.34M
|
+49,992
|
+426%
|
|
|
25
|
Opus Point Partners Management
New York
|
$1.71M
|
+$1.61M
|
+60,000
|
New
|
|
