|
1
|
EcoR1 Capital
San Francisco,
California
|
$143M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$71.6M
|
-$36.5M
|
-1,286,686
|
-31%
|
|
|
3
|
BVF Inc
San Francisco,
California
|
$38.9M
|
-$8.35M
|
-294,387
|
-16%
|
|
|
4
|
Deerfield Management
New York
|
$35M
|
–
|
–
|
–
|
|
|
5
|
Prosight Management
Dallas,
Texas
|
$33.5M
|
+$11.9M
|
+418,468
|
+45%
|
|
|
6
|
Segall Bryant & Hamill
Chicago,
Illinois
|
$19.8M
|
-$1.96M
|
-68,963
|
-8%
|
|
|
7
|
Primecap Management
Pasadena,
California
|
$17.8M
|
+$142K
|
+5,000
|
+0.7%
|
|
|
8
|
|
$13.9M
|
+$1.17M
|
+41,067
|
+8%
|
|
|
9
|
Finepoint Capital
Boston,
Massachusetts
|
$13.4M
|
+$1.11M
|
+39,003
|
+8%
|
|
|
10
|
Hudson Bay Capital Management
Stamford,
Connecticut
|
$13M
|
+$2.63M
|
+92,600
|
+21%
|
|
|
11
|
Newtyn Management
New York
|
$12.4M
|
+$3.8M
|
+134,000
|
+37%
|
|
|
12
|
Stonepine Capital Management
Bend,
Oregon
|
$12M
|
+$2.59M
|
+91,366
|
+23%
|
|
|
13
|
Wellington Management Group
Boston,
Massachusetts
|
$8.55M
|
-$3.68M
|
-129,833
|
-27%
|
|
|
14
|
Millennium Management
New York
|
$8.47M
|
+$485K
|
+17,089
|
+5%
|
|
|
15
|
Renaissance Technologies
New York
|
$6.71M
|
+$122K
|
+4,300
|
+2%
|
|
|
16
|
DME Capital Management
New York
|
$5.82M
|
+$2.13M
|
+75,000
|
+47%
|
|
|
17
|
Vestal Point Capital
New York
|
$4.46M
|
+$1.42M
|
+50,000
|
+38%
|
|
|
18
|
Citadel Advisors
Miami,
Florida
|
$3.81M
|
+$3.76M
|
+132,439
|
+616%
|
|
|
19
|
DAFNA Capital Management
Los Angeles,
California
|
$3.23M
|
–
|
–
|
–
|
|
|
20
|
|
$2.97M
|
–
|
–
|
–
|
|
|
21
|
|
$2.82M
|
+$2.56M
|
+90,067
|
+381%
|
|
|
22
|
AlphaCentric Advisors
San Juan,
Puerto Rico
|
$2.69M
|
+$99.3K
|
+3,500
|
+3%
|
|
|
23
|
Ameriprise
Minneapolis,
Minnesota
|
$2.63M
|
+$51.2K
|
+1,806
|
+2%
|
|
|
24
|
|
$1.98M
|
-$331K
|
-11,650
|
-13%
|
|
|
25
|
683 Capital Management
New York
|
$1.73M
|
+$341K
|
+12,000
|
+21%
|
|
