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LKFT

Lakefront Biotherapeutics American Depositary Shares
LKFT

85 hedge funds and large institutions have $887M invested in Lakefront Biotherapeutics American Depositary Shares in 2025 Q2 according to their latest regulatory filings, with 21 funds opening new positions, 25 increasing their positions, 24 reducing their positions, and 18 closing their positions.

New
Increased
Maintained
Reduced
Closed

80% more call options, than puts

Call options by funds: $28.7M | Put options by funds: $16M

17% more first-time investments, than exits

New positions opened: 21 | Existing positions closed: 18

13% more capital invested

Capital invested by funds: $783M → $887M (+$104M)

2% more funds holding

Funds holding: 83 → 85 (+2)

4% more repeat investments, than reductions

Existing positions increased: 25 | Existing positions reduced: 24

0.77% more ownership

Funds ownership: 47.33% → 48.1% (+0.77%)

0% more funds holding in top 10

Funds holding in top 10: 4 → 4 (0)

Holders
85
Holders Change
+2
Holders Change %
+2.41%
% of All Funds
1.12%
Holding in Top 10
4
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.05%
New
21
Increased
25
Reduced
24
Closed
18
Calls
$28.7M
Puts
$16M
Net Calls
+$12.8M
Net Calls Change
+$15M

Top Buyers

Rank Fund Capital Flow
1
MAP
Madison Avenue Partners
New York
+$50.3M
2
EC
EcoR1 Capital
California
+$23.6M
3
PM
Prosight Management
Texas
+$12.3M
4
Point72 Asset Management
Point72 Asset Management
Connecticut
+$9.16M
5
Renaissance Technologies
Renaissance Technologies
New York
+$3.59M

Top Sellers

Rank Fund Capital Flow
1
BI
BVF Inc
California
-$36.5M
2
DTC
Deep Track Capital
Connecticut
-$18.6M
3
FC
Finepoint Capital
Massachusetts
-$16.5M
4
NM
Newtyn Management
New York
-$5.02M
5
VPC
Vestal Point Capital
New York
-$5.02M
Name Holding Trade Value Shares
Change 		Change in
Stake
GS
1
Gilead Sciences
California
$468M – – –
TCM
2
Tang Capital Management
California
$112M +$759K +28,314 +0.7%
MAP
3
Madison Avenue Partners
New York
$52.5M +$50.3M +1,877,011 New
PM
4
Prosight Management
Texas
$49.6M +$12.3M +458,751 +35%
Fidelity Investments
5
Fidelity Investments
Massachusetts
$43.3M -$263K -9,828 -0.6%
EC
6
EcoR1 Capital
California
$29M +$23.6M +881,939 +569%
Hudson Bay Capital Management
7
Hudson Bay Capital Management
Connecticut
$14.4M -$1.34M -50,000 -9%
SBH
8
Segall Bryant & Hamill
Illinois
$14M -$4.03M -150,384 -23%
DCM
9
DME Capital Management
New York
$13.5M – – –
Renaissance Technologies
10
Renaissance Technologies
New York
$13M +$3.59M +133,900 +40%
Point72 Asset Management
11
Point72 Asset Management
Connecticut
$9.56M +$9.16M +341,500 New
UBS Group
12
UBS Group
Switzerland
$6.68M +$3.47M +129,513 +119%
BlackRock
13
BlackRock
New York
$6.33M -$748K -27,895 -11%
Millennium Management
14
Millennium Management
New York
$5.34M +$3.42M +127,645 +202%
D.E. Shaw & Co
15
D.E. Shaw & Co
New York
$4.29M +$2.42M +90,165 +143%
Primecap Management
16
Primecap Management
California
$4.01M -$105K -3,900 -3%
DCM
17
DAFNA Capital Management
California
$3.64M – – –
Norges Bank
18
Norges Bank
Norway
$3.36M – – –
CC
19
Centiva Capital
New York
$2.66M +$1.51M +56,354 +146%
Voloridge Investment Management
20
Voloridge Investment Management
Florida
$2.39M +$2.29M +85,401 New
Royal Bank of Canada
21
Royal Bank of Canada
Ontario, Canada
$2.26M +$2.14M +79,980 +9,068%
TRCT
22
Tower Research Capital (TRC)
New York
$2.21M +$2.08M +77,750 +5,614%
Optiver Holding
23
Optiver Holding
Netherlands
$2.21M +$1.3M +48,521 +160%
Morgan Stanley
24
Morgan Stanley
New York
$1.85M +$1.09M +40,757 +160%
Goldman Sachs
25
Goldman Sachs
New York
$1.59M +$1.52M +56,731 New
1
2 3 4 5

LKFT Hedge Fund Activity: Q2 2025 in Review

85 of the 7,598 institutional investors tracked by Wall St. Rank reported a position in Lakefront Biotherapeutics American Depositary Shares (LKFT) for Q2 2025, worth a combined $887M — up 13% from $783M a quarter earlier.

Buyers outnumbered sellers: 21 funds opened new LKFT positions and 18 closed out — a net gain of 3 holders — while 25 added to existing stakes and 24 trimmed.

The largest buyer was Madison Avenue Partners, opening a new position worth an estimated $50.3M. The largest seller was BVF Inc, exiting entirely with an estimated $36.5M sold.

  • 85 institutional investors held Lakefront Biotherapeutics American Depositary Shares (LKFT) as of Q2 2025, up from 83 in Q1 2025.
  • Funds reported $887M of Lakefront Biotherapeutics American Depositary Shares stock for Q2 2025, up 13% quarter-over-quarter.
  • 21 funds opened new Lakefront Biotherapeutics American Depositary Shares positions in Q2 2025 and 18 closed out, a net change of +3 holders.
  • The largest Lakefront Biotherapeutics American Depositary Shares buyer in Q2 2025 was Madison Avenue Partners, an estimated $50.3M added.
  • The largest Lakefront Biotherapeutics American Depositary Shares seller in Q2 2025 was BVF Inc, an estimated $36.5M sold.

Based on aggregated 13F filings for Q2 2025.