|
1
|
Tang Capital Management
San Diego,
California
|
$43.5M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$35.8M
|
–
|
–
|
–
|
|
|
3
|
|
$17.7M
|
+$46.6K
|
+4,929
|
+0.2%
|
|
|
4
|
Baker Bros. Advisors
New York
|
$13.7M
|
–
|
–
|
–
|
|
|
5
|
|
$12.8M
|
+$365K
|
+38,634
|
+3%
|
|
|
6
|
VHCP Management III
New York
|
$11M
|
–
|
–
|
–
|
|
|
7
|
Sectoral Asset Management
Montreal,
Quebec, Canada
|
$10.2M
|
-$4.71M
|
-498,900
|
-30%
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$9.05M
|
-$156K
|
-16,511
|
-2%
|
|
|
9
|
|
$7.48M
|
+$4.06M
|
+429,436
|
+102%
|
|
|
10
|
Boxer Capital
San Diego,
California
|
$6.82M
|
+$1.89M
|
+200,000
|
+35%
|
|
|
11
|
VHCP Management II
New York
|
$4.56M
|
–
|
–
|
–
|
|
|
12
|
Prudential Financial
Newark,
New Jersey
|
$3.92M
|
-$2.08K
|
-220
|
-0.1%
|
|
|
13
|
State Street
Boston,
Massachusetts
|
$3.76M
|
+$112K
|
+11,890
|
+3%
|
|
|
14
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$3.74M
|
–
|
–
|
–
|
|
|
15
|
SG Americas Securities
New York
|
$3.31M
|
+$2.83M
|
+299,995
|
+395%
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$3.01M
|
+$239K
|
+25,259
|
+8%
|
|
|
17
|
Millennium Management
New York
|
$2.88M
|
-$6.86M
|
-725,831
|
-69%
|
|
|
18
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$2.87M
|
–
|
–
|
–
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$2.64M
|
+$224K
|
+23,735
|
+9%
|
|
|
20
|
|
$2.32M
|
+$1.06M
|
+112,429
|
+74%
|
|
|
21
|
|
$2.11M
|
–
|
–
|
–
|
|
|
22
|
Broadfin Capital
New York
|
$1.6M
|
-$6.71M
|
-709,916
|
-80%
|
|
|
23
|
Spark Investment Management
New York
|
$1.26M
|
-$820K
|
-86,764
|
-38%
|
|
|
24
|
Charles Schwab
San Francisco,
California
|
$1.14M
|
+$25.2K
|
+2,667
|
+2%
|
|
|
25
|
|
$1.06M
|
+$51.5K
|
+5,451
|
+5%
|
|
