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Keros Therapeutics

166 hedge funds and large institutions have $409M invested in Keros Therapeutics in 2025 Q4 according to their latest regulatory filings, with 41 funds opening new positions, 39 increasing their positions, 73 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

130% more call options, than puts

Call options by funds: $10.4M | Put options by funds: $4.54M

58% more first-time investments, than exits

New positions opened: 41 | Existing positions closed: 26

7% more funds holding

Funds holding: 155166 (+11)

20.97% less ownership

Funds ownership: 86.87%65.89% (-21%)

27% less capital invested

Capital invested by funds: $559M → $409M (-$150M)

47% less repeat investments, than reductions

Existing positions increased: 39 | Existing positions reduced: 73

67% less funds holding in top 10

Funds holding in top 10: 31 (-2)

Holders
166
Holders Change
+11
Holders Change %
+7.1%
% of All Funds
2.02%
Holding in Top 10
1
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-66.67%
% of All Funds
0.01%
New
41
Increased
39
Reduced
73
Closed
26
Calls
$10.4M
Puts
$4.54M
Net Calls
+$5.91M
Net Calls Change
+$3.31M
Name Holding Trade Value Shares
Change
Change in
Stake
BlackRock
1
BlackRock
New York
$46.6M -$7.48M -426,621 -16%
Vanguard Group
2
Vanguard Group
Pennsylvania
$31.1M -$20.9M -1,193,422 -44%
Arrowstreet Capital
3
Arrowstreet Capital
Massachusetts
$27.2M +$18.9M +1,075,762 +416%
State Street
4
State Street
Massachusetts
$21.9M -$3.98M -226,985 -17%
MAP
5
Madison Avenue Partners
New York
$16.8M -$33.1M -1,884,511 -70%
O
6
OrbiMed
New York
$16.4M -$3.76M -214,522 -21%
Qube Research & Technologies (QRT)
7
Qube Research & Technologies (QRT)
United Kingdom
$16M +$8.44M +480,796 +159%
Jacobs Levy Equity Management
8
Jacobs Levy Equity Management
New Jersey
$15.6M +$2.83M +161,336 +27%
D.E. Shaw & Co
9
D.E. Shaw & Co
New York
$15.4M -$10.1M -575,952 -43%
Federated Hermes
10
Federated Hermes
Pennsylvania
$13.3M +$2.47M +140,564 +27%
Geode Capital Management
11
Geode Capital Management
Massachusetts
$12.9M -$3.55M -202,155 -24%
Renaissance Technologies
12
Renaissance Technologies
New York
$12M +$7.67M +436,986 +282%
Goldman Sachs
13
Goldman Sachs
New York
$12M -$12.9M -734,966 -55%
Citadel Advisors
14
Citadel Advisors
Florida
$9.62M +$5.2M +296,376 +168%
NCM
15
Nantahala Capital Management
Connecticut
$7.34M -$15.3M -872,770 -71%
Connor, Clark & Lunn Investment Management (CC&L)
16
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$6.54M -$242K -13,808 -4%
Two Sigma Investments
17
Two Sigma Investments
New York
$6.48M +$4.14M +235,916 +286%
HF
18
HRT Financial
New York
$5.31M +$3.83M +218,092 +510%
WAM
19
Weiss Asset Management
Massachusetts
$5.17M +$4.46M +254,063 New
Northern Trust
20
Northern Trust
Illinois
$5.1M -$1.44M -82,187 -25%
Morgan Stanley
21
Morgan Stanley
New York
$4.69M -$2.89M -164,611 -42%
Millennium Management
22
Millennium Management
New York
$4.48M +$2.93M +166,863 +313%
Deutsche Bank
23
Deutsche Bank
Germany
$3.98M +$3.02M +172,022 +740%
AG
24
Algert Global
California
$3.94M +$2.56M +145,828 +305%
Man Group
25
Man Group
United Kingdom
$3.87M -$46.4K -2,647 -1%

KROS Hedge Fund Activity: Q4 2025 in Review

166 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Keros Therapeutics (KROS) for Q4 2025, worth a combined $409M — down 27% from $559M a quarter earlier.

Buyers outnumbered sellers: 41 funds opened new KROS positions and 26 closed out — a net gain of 15 holders — while 39 added to existing stakes and 73 trimmed.

The largest buyer was Arrowstreet Capital, adding an estimated $18.9M. The largest seller was ADAR1 Capital Management, cutting an estimated $94.2M.

  • 166 institutional investors held Keros Therapeutics (KROS) as of Q4 2025, up from 155 in Q3 2025.
  • Funds reported $409M of Keros Therapeutics stock for Q4 2025, down 27% quarter-over-quarter.
  • 41 funds opened new Keros Therapeutics positions in Q4 2025 and 26 closed out, a net change of +15 holders.
  • The largest Keros Therapeutics buyer in Q4 2025 was Arrowstreet Capital, an estimated $18.9M added.
  • The largest Keros Therapeutics seller in Q4 2025 was ADAR1 Capital Management, an estimated $94.2M sold.

Based on aggregated 13F filings for Q4 2025.