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Kiniksa Pharmaceuticals

189 hedge funds and large institutions have $1.1B invested in Kiniksa Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 48 funds opening new positions, 65 increasing their positions, 63 reducing their positions, and 33 closing their positions.

New
Increased
Maintained
Reduced
Closed

50% more funds holding in top 10

Funds holding in top 10: 23 (+1)

45% more first-time investments, than exits

New positions opened: 48 | Existing positions closed: 33

24% more capital invested

Capital invested by funds: $889M → $1.1B (+$213M)

7% more funds holding

Funds holding: 176189 (+13)

3% more repeat investments, than reductions

Existing positions increased: 65 | Existing positions reduced: 63

1.18% less ownership

Funds ownership: 95.32%94.14% (-1.2%)

77% less call options, than puts

Call options by funds: $8.22M | Put options by funds: $36.2M

Holders
189
Holders Change
+13
Holders Change %
+7.39%
% of All Funds
2.49%
Holding in Top 10
3
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+50%
% of All Funds
0.04%
New
48
Increased
65
Reduced
63
Closed
33
Calls
$8.22M
Puts
$36.2M
Net Calls
-$28M
Net Calls Change
-$28.1M
Name Holding Trade Value Shares
Change
Change in
Stake
RCMNY
1
Rubric Capital Management (New York)
New York
$108M +$13.4M +526,567 +16%
Vanguard Group
2
Vanguard Group
Pennsylvania
$86.7M -$5.79M -227,499 -7%
BBA
3
Baker Bros. Advisors
New York
$78.2M +$162K +6,346 +0.2%
TCM
4
Tang Capital Management
California
$64.4M +$5.35M +210,030 +10%
FFM
5
Fairmount Funds Management
Pennsylvania
$49.1M +$17.1M +670,591 +61%
Acadian Asset Management
6
Acadian Asset Management
Massachusetts
$35.1M +$5.95M +233,668 +23%
B
7
Braidwell
Connecticut
$30.5M -$21.9M -860,329 -44%
Morgan Stanley
8
Morgan Stanley
New York
$29.5M -$258K -10,120 -0.9%
Millennium Management
9
Millennium Management
New York
$28.2M +$4.4M +172,844 +20%
Pictet Asset Management
10
Pictet Asset Management
Switzerland
$27.2M -$3.8M -149,334 -13%
Qube Research & Technologies (QRT)
11
Qube Research & Technologies (QRT)
United Kingdom
$24.6M +$16.6M +653,236 +278%
Point72 Asset Management
12
Point72 Asset Management
Connecticut
$23.5M -$7.66M -300,862 -26%
Fidelity Investments
13
Fidelity Investments
Massachusetts
$22.3M +$70.1K +2,755 +0.3%
D.E. Shaw & Co
14
D.E. Shaw & Co
New York
$21.9M +$10M +393,560 +99%
Arrowstreet Capital
15
Arrowstreet Capital
Massachusetts
$20.3M +$18.7M +735,417 New
BlackRock
16
BlackRock
New York
$19.4M -$69.5M -2,729,819 -80%
CSS
17
Cubist Systematic Strategies
Connecticut
$18.2M +$11.4M +447,536 +213%
Dimensional Fund Advisors
18
Dimensional Fund Advisors
Texas
$17.9M -$3.16M -123,967 -16%
DCM
19
Driehaus Capital Management
Illinois
$17.9M +$934K +36,702 +6%
RHJA
20
Rice Hall James & Associates
California
$17.7M +$348K +13,688 +2%
Connor, Clark & Lunn Investment Management (CC&L)
21
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$17.3M +$5.7M +223,946 +56%
Jane Street
22
Jane Street
New York
$15.5M +$10.9M +429,101 +332%
PHP
23
Parkman Healthcare Partners
Connecticut
$13.5M -$6.97M -273,825 -36%
ACH
24
ArrowMark Colorado Holdings
Colorado
$12.9M -$1.78M -69,808 -13%
TI
25
Trexquant Investment
Connecticut
$12.6M +$5.61M +220,504 +93%

KNSA Hedge Fund Activity: Q2 2025 in Review

189 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Kiniksa Pharmaceuticals (KNSA) for Q2 2025, worth a combined $1.1B — up 24% from $889M a quarter earlier.

Buyers outnumbered sellers: 48 funds opened new KNSA positions and 33 closed out — a net gain of 15 holders — while 65 added to existing stakes and 63 trimmed.

The largest buyer was Arrowstreet Capital, opening a new position worth an estimated $18.7M. The largest seller was BlackRock, cutting an estimated $69.5M.

  • 189 institutional investors held Kiniksa Pharmaceuticals (KNSA) as of Q2 2025, up from 176 in Q1 2025.
  • Funds reported $1.1B of Kiniksa Pharmaceuticals stock for Q2 2025, up 24% quarter-over-quarter.
  • 48 funds opened new Kiniksa Pharmaceuticals positions in Q2 2025 and 33 closed out, a net change of +15 holders.
  • The largest Kiniksa Pharmaceuticals buyer in Q2 2025 was Arrowstreet Capital, an estimated $18.7M added.
  • The largest Kiniksa Pharmaceuticals seller in Q2 2025 was BlackRock, an estimated $69.5M sold.

Based on aggregated 13F filings for Q2 2025.