|
1
|
Baillie Gifford & Co
Edinburgh,
United Kingdom
|
$482M
|
-$15M
|
-300,612
|
-3%
|
|
|
2
|
Crestline Management
Fort Worth,
Texas
|
$349M
|
-$85.7M
|
-1,717,168
|
-18%
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
$320M
|
+$13.9M
|
+278,148
|
+4%
|
|
|
4
|
Capital International Investors
Los Angeles,
California
|
$287M
|
+$28.7M
|
+575,160
|
+10%
|
|
|
5
|
|
$221M
|
+$14.9M
|
+299,586
|
+7%
|
|
|
6
|
Fidelity Investments
Boston,
Massachusetts
|
$125M
|
+$49.3M
|
+987,489
|
+56%
|
|
|
7
|
Capital World Investors
Los Angeles,
California
|
$104M
|
–
|
–
|
–
|
|
|
8
|
Janus Henderson Group
London,
|
$92.3M
|
+$59.2M
|
+1,186,190
|
+142%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$90M
|
-$35M
|
-702,070
|
-26%
|
|
|
10
|
BB Biotech
Schaffhausen,
Switzerland
|
$88M
|
-$6.48M
|
-130,000
|
-6%
|
|
|
11
|
|
$86M
|
-$3.95M
|
-79,191
|
-4%
|
|
|
12
|
Biomark Capital Management
Greenwich,
Connecticut
|
$85.2M
|
–
|
–
|
–
|
|
|
13
|
PFM Health Sciences
San Francisco,
California
|
$84.6M
|
+$20M
|
+400,213
|
+28%
|
|
|
14
|
|
$83.9M
|
-$10.3M
|
-206,420
|
-10%
|
|
|
15
|
Jennison Associates
New York
|
$78.9M
|
-$13.1M
|
-263,472
|
-13%
|
|
|
16
|
|
$72.9M
|
+$33.6M
|
+674,093
|
+73%
|
|
|
17
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$55.4M
|
-$5.08M
|
-101,881
|
-8%
|
|
|
18
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$50.1M
|
-$1.77M
|
-35,542
|
-3%
|
|
|
19
|
First Trust Advisors
Wheaton,
Illinois
|
$46.1M
|
-$14.4M
|
-287,858
|
-22%
|
|
|
20
|
Temasek Holdings
Singapore
|
$41.9M
|
–
|
–
|
–
|
|
|
21
|
Capital Guardian Trust
Los Angeles,
California
|
$40.7M
|
+$2.84M
|
+56,890
|
+7%
|
|
|
22
|
Mitsubishi UFJ Trust & Banking
Tokyo,
Japan
|
$40.2M
|
-$922K
|
-18,480
|
-2%
|
|
|
23
|
Geode Capital Management
Boston,
Massachusetts
|
$35.1M
|
+$3.72M
|
+74,519
|
+11%
|
|
|
24
|
Omega Fund Management
Boston,
Massachusetts
|
$34.4M
|
-$16M
|
-321,048
|
-30%
|
|
|
25
|
ARK Investment Management
St. Petersburg,
Florida
|
$31.2M
|
+$8.05M
|
+161,380
|
+31%
|
|
