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Jazz Pharmaceuticals

573 hedge funds and large institutions have $10.5B invested in Jazz Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 129 funds opening new positions, 180 increasing their positions, 193 reducing their positions, and 51 closing their positions.

New
Increased
Maintained
Reduced
Closed

244% more call options, than puts

Call options by funds: $172M | Put options by funds: $50.2M

153% more first-time investments, than exits

New positions opened: 129 | Existing positions closed: 51

31% more capital invested

Capital invested by funds: $8.01B → $10.5B (+$2.48B)

25% more funds holding in top 10

Funds holding in top 10: 1215 (+3)

14% more funds holding

Funds holding: 502573 (+71)

1.41% more ownership

Funds ownership: 100.16%101.57% (+1.4%)

7% less repeat investments, than reductions

Existing positions increased: 180 | Existing positions reduced: 193

Holders
573
Holders Change
+71
Holders Change %
+14.14%
% of All Funds
6.97%
Holding in Top 10
15
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+25%
% of All Funds
0.18%
New
129
Increased
180
Reduced
193
Closed
51
Calls
$172M
Puts
$50.2M
Net Calls
+$122M
Net Calls Change
+$16.2M
Name Holding Trade Value Shares
Change
Change in
Stake
Vanguard Group
1
Vanguard Group
Pennsylvania
$1.01B +$1.56M +10,197 +0.2%
BlackRock
2
BlackRock
New York
$927M -$16.6M -108,071 -2%
Capital World Investors
3
Capital World Investors
California
$453M +$17.1M +111,735 +4%
Dimensional Fund Advisors
4
Dimensional Fund Advisors
Texas
$446M -$32.7M -213,349 -8%
LSV Asset Management
5
LSV Asset Management
Illinois
$418M -$8.57M -55,901 -2%
State Street
6
State Street
Massachusetts
$312M -$4.61M -30,093 -2%
Franklin Resources
7
Franklin Resources
California
$309M +$173M +1,129,995 +164%
EC
8
EcoR1 Capital
California
$290M
Fuller & Thaler Asset Management
9
Fuller & Thaler Asset Management
California
$285M +$7.82M +50,996 +3%
Ameriprise
10
Ameriprise
Minnesota
$259M -$50M -326,365 -18%
Millennium Management
11
Millennium Management
New York
$204M +$143M +933,604 +347%
Geode Capital Management
12
Geode Capital Management
Massachusetts
$204M +$176K +1,150 +0.1%
Bank of New York Mellon
13
Bank of New York Mellon
New York
$198M +$110M +715,361 +160%
Swedbank
14
Swedbank
Sweden
$188M +$4.43M +28,882 +3%
JP Morgan Chase
15
JP Morgan Chase
New York
$178M -$126M -822,517 -44%
SI
16
Sofinnova Investments
California
$163M +$56.9M +371,032 +63%
Bank of America
17
Bank of America
North Carolina
$156M -$8.09M -52,757 -5%
AQR Capital Management
18
AQR Capital Management
Connecticut
$149M +$27.3M +178,326 +26%
Renaissance Technologies
19
Renaissance Technologies
New York
$142M -$13.5M -88,100 -10%
Fidelity Investments
20
Fidelity Investments
Massachusetts
$136M +$18.2M +118,789 +17%
BNP Paribas Asset Management
21
BNP Paribas Asset Management
France
$120M +$22.8M +148,595 +27%
Pacer Advisors
22
Pacer Advisors
Pennsylvania
$110M +$16.4M +107,144 +20%
Morgan Stanley
23
Morgan Stanley
New York
$109M -$12M -78,446 -11%
GC
24
GMT Capital
Georgia
$109M -$23.7M -154,300 -19%
Allianz Asset Management
25
Allianz Asset Management
Germany
$102M +$37.2M +242,892 +68%

JAZZ Hedge Fund Activity: Q4 2025 in Review

573 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Jazz Pharmaceuticals (JAZZ) for Q4 2025, worth a combined $10.5B — up 31% from $8.01B a quarter earlier.

Buyers outnumbered sellers: 129 funds opened new JAZZ positions and 51 closed out — a net gain of 78 holders — while 180 added to existing stakes and 193 trimmed.

The largest buyer was Franklin Resources, adding an estimated $173M. The largest seller was JP Morgan Chase, cutting an estimated $126M.

  • 573 institutional investors held Jazz Pharmaceuticals (JAZZ) as of Q4 2025, up from 502 in Q3 2025.
  • Funds reported $10.5B of Jazz Pharmaceuticals stock for Q4 2025, up 31% quarter-over-quarter.
  • 129 funds opened new Jazz Pharmaceuticals positions in Q4 2025 and 51 closed out, a net change of +78 holders.
  • The largest Jazz Pharmaceuticals buyer in Q4 2025 was Franklin Resources, an estimated $173M added.
  • The largest Jazz Pharmaceuticals seller in Q4 2025 was JP Morgan Chase, an estimated $126M sold.

Based on aggregated 13F filings for Q4 2025.