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Jazz Pharmaceuticals

573 hedge funds and large institutions have $10.5B invested in Jazz Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 129 funds opening new positions, 180 increasing their positions, 193 reducing their positions, and 51 closing their positions.

New
Increased
Maintained
Reduced
Closed

244% more call options, than puts

Call options by funds: $172M | Put options by funds: $50.2M

153% more first-time investments, than exits

New positions opened: 129 | Existing positions closed: 51

31% more capital invested

Capital invested by funds: $8.01B → $10.5B (+$2.48B)

25% more funds holding in top 10

Funds holding in top 10: 1215 (+3)

14% more funds holding

Funds holding: 502573 (+71)

1.41% more ownership

Funds ownership: 100.16%101.57% (+1.4%)

7% less repeat investments, than reductions

Existing positions increased: 180 | Existing positions reduced: 193

Holders
573
Holders Change
+71
Holders Change %
+14.14%
% of All Funds
6.97%
Holding in Top 10
15
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+25%
% of All Funds
0.18%
New
129
Increased
180
Reduced
193
Closed
51
Calls
$172M
Puts
$50.2M
Net Calls
+$122M
Net Calls Change
+$16.2M
Name Holding Trade Value Shares
Change
Change in
Stake
D.E. Shaw & Co
51
D.E. Shaw & Co
New York
$33.9M +$11.5M +74,936 +60%
Invesco
52
Invesco
Georgia
$32.5M +$3.08M +20,090 +12%
WCM
53
Wedge Capital Management
North Carolina
$32.1M -$3.42M -22,307 -11%
Pictet Asset Management
54
Pictet Asset Management
Switzerland
$31.5M -$5.14M -33,547 -15%
FCM
55
Frontier Capital Management
Massachusetts
$31M +$22M +143,692 +373%
Raymond James Financial
56
Raymond James Financial
Florida
$30.2M +$2.83M +18,470 +12%
Point72 Asset Management
57
Point72 Asset Management
Connecticut
$29.8M +$25M +163,145 +1,376%
Goldman Sachs
58
Goldman Sachs
New York
$29.7M +$1.44M +9,409 +6%
QCM
59
Quantinno Capital Management
New York
$29.6M +$21.1M +137,468 +373%
PA
60
Perceptive Advisors
New York
$28.9M +$26.1M +170,000 New
KAM
61
Krensavage Asset Management
New York
$28.5M
Retirement Systems of Alabama
62
Retirement Systems of Alabama
Alabama
$28.5M -$3.17M -20,703 -11%
IC
63
Ikarian Capital
Texas
$27.3M +$12.7M +82,567 +106%
Aristotle Capital Management
64
Aristotle Capital Management
California
$27M +$120K +781 +0.5%
RhumbLine Advisers
65
RhumbLine Advisers
Massachusetts
$26.9M -$985K -6,427 -4%
PL
66
Perpetual Ltd
Australia
$26.3M -$68.7M -447,997 -74%
UBS AM
67
UBS AM
Illinois
$25.2M -$3.28M -21,364 -13%
Deutsche Bank
68
Deutsche Bank
Germany
$23.8M +$19.1M +124,864 +810%
SSA
69
Schonfeld Strategic Advisors
New York
$23.7M -$45.6M -297,226 -68%
ECM
70
ExodusPoint Capital Management
New York
$23.4M +$17.9M +116,542 +555%
SG Americas Securities
71
SG Americas Securities
New York
$23.1M +$20.2M +131,592 +2,969%
Principal Financial Group
72
Principal Financial Group
Iowa
$22.2M -$620K -4,041 -3%
SC
73
SummitTX Capital
Texas
$21.6M +$15.9M +103,790 +451%
Stifel Financial
74
Stifel Financial
Missouri
$20.9M -$486K -3,171 -3%
Hotchkis & Wiley Capital Management
75
Hotchkis & Wiley Capital Management
California
$20.2M -$2.93M -19,127 -14%

JAZZ Hedge Fund Activity: Q4 2025 in Review

573 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Jazz Pharmaceuticals (JAZZ) for Q4 2025, worth a combined $10.5B — up 31% from $8.01B a quarter earlier.

Buyers outnumbered sellers: 129 funds opened new JAZZ positions and 51 closed out — a net gain of 78 holders — while 180 added to existing stakes and 193 trimmed.

The largest buyer was Franklin Resources, adding an estimated $173M. The largest seller was JP Morgan Chase, cutting an estimated $126M.

  • 573 institutional investors held Jazz Pharmaceuticals (JAZZ) as of Q4 2025, up from 502 in Q3 2025.
  • Funds reported $10.5B of Jazz Pharmaceuticals stock for Q4 2025, up 31% quarter-over-quarter.
  • 129 funds opened new Jazz Pharmaceuticals positions in Q4 2025 and 51 closed out, a net change of +78 holders.
  • The largest Jazz Pharmaceuticals buyer in Q4 2025 was Franklin Resources, an estimated $173M added.
  • The largest Jazz Pharmaceuticals seller in Q4 2025 was JP Morgan Chase, an estimated $126M sold.

Based on aggregated 13F filings for Q4 2025.