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Jazz Pharmaceuticals

573 hedge funds and large institutions have $10.5B invested in Jazz Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 129 funds opening new positions, 180 increasing their positions, 193 reducing their positions, and 51 closing their positions.

New
Increased
Maintained
Reduced
Closed

244% more call options, than puts

Call options by funds: $172M | Put options by funds: $50.2M

153% more first-time investments, than exits

New positions opened: 129 | Existing positions closed: 51

31% more capital invested

Capital invested by funds: $8.01B → $10.5B (+$2.48B)

25% more funds holding in top 10

Funds holding in top 10: 1215 (+3)

14% more funds holding

Funds holding: 502573 (+71)

1.41% more ownership

Funds ownership: 100.16%101.57% (+1.4%)

7% less repeat investments, than reductions

Existing positions increased: 180 | Existing positions reduced: 193

Holders
573
Holders Change
+71
Holders Change %
+14.14%
% of All Funds
6.97%
Holding in Top 10
15
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+25%
% of All Funds
0.18%
New
129
Increased
180
Reduced
193
Closed
51
Calls
$172M
Puts
$50.2M
Net Calls
+$122M
Net Calls Change
+$16.2M
Name Holding Trade Value Shares
Change
Change in
Stake
Holocene Advisors
26
Holocene Advisors
New York
$100M -$2.36M -15,374 -3%
Adage Capital Partners
27
Adage Capital Partners
Massachusetts
$93.2M +$60.6M +395,000 +258%
Manulife (Manufacturers Life Insurance)
28
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$93.1M +$4.82M +31,432 +6%
Qube Research & Technologies (QRT)
29
Qube Research & Technologies (QRT)
United Kingdom
$85.1M +$68.1M +444,242 +790%
Northern Trust
30
Northern Trust
Illinois
$81.1M -$4.09M -26,679 -5%
UBS Group
31
UBS Group
Switzerland
$80.4M +$2.83M +18,485 +4%
PCM
32
Polaris Capital Management
Massachusetts
$73.5M -$12.4M -81,000 -16%
GKIM
33
GW&K Investment Management
Massachusetts
$72.7M -$4.15M -27,068 -6%
Charles Schwab
34
Charles Schwab
California
$72.1M -$6.62M -43,193 -9%
GAM
35
Goldentree Asset Management
New York
$71.3M -$110M -716,765 -63%
SFM
36
Systematic Financial Management
New Jersey
$67.5M +$389K +2,536 +0.6%
BTW
37
Boston Trust Walden
Massachusetts
$67M -$2.29M -14,916 -4%
N
38
Nuveen
North Carolina
$64.9M -$1.04M -6,764 -2%
Alyeska Investment Group
39
Alyeska Investment Group
Illinois
$55M +$18M +117,430 +57%
Citadel Advisors
40
Citadel Advisors
Florida
$52.9M -$87.8M -572,825 -65%
ITP
41
Iron Triangle Partners
Connecticut
$49.7M +$21.8M +142,170 +95%
American Century Companies
42
American Century Companies
Missouri
$49.5M +$11.5M +74,928 +35%
TSW
43
Thompson Siegel & Walmsley
Virginia
$49.3M -$12.8M -83,719 -22%
VPC
44
Vestal Point Capital
New York
$49.3M -$32.2M -210,000 -42%
Rockefeller Capital Management
45
Rockefeller Capital Management
New York
$45.1M -$1.81M -11,816 -4%
Victory Capital Management
46
Victory Capital Management
Texas
$42.4M -$8.53M -55,663 -18%
SVCM
47
Saturn V Capital Management
Texas
$42.2M -$8.05M -52,540 -17%
Zurich Cantonal Bank
48
Zurich Cantonal Bank
Switzerland
$38.9M +$30.2M +197,072 +624%
Bank of Montreal
49
Bank of Montreal
Ontario, Canada
$38M -$17.5M -113,841 -34%
LGM
50
Logos Global Management
California
$34M

JAZZ Hedge Fund Activity: Q4 2025 in Review

573 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Jazz Pharmaceuticals (JAZZ) for Q4 2025, worth a combined $10.5B — up 31% from $8.01B a quarter earlier.

Buyers outnumbered sellers: 129 funds opened new JAZZ positions and 51 closed out — a net gain of 78 holders — while 180 added to existing stakes and 193 trimmed.

The largest buyer was Franklin Resources, adding an estimated $173M. The largest seller was JP Morgan Chase, cutting an estimated $126M.

  • 573 institutional investors held Jazz Pharmaceuticals (JAZZ) as of Q4 2025, up from 502 in Q3 2025.
  • Funds reported $10.5B of Jazz Pharmaceuticals stock for Q4 2025, up 31% quarter-over-quarter.
  • 129 funds opened new Jazz Pharmaceuticals positions in Q4 2025 and 51 closed out, a net change of +78 holders.
  • The largest Jazz Pharmaceuticals buyer in Q4 2025 was Franklin Resources, an estimated $173M added.
  • The largest Jazz Pharmaceuticals seller in Q4 2025 was JP Morgan Chase, an estimated $126M sold.

Based on aggregated 13F filings for Q4 2025.