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Jazz Pharmaceuticals

573 hedge funds and large institutions have $10.5B invested in Jazz Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 129 funds opening new positions, 180 increasing their positions, 193 reducing their positions, and 51 closing their positions.

New
Increased
Maintained
Reduced
Closed

244% more call options, than puts

Call options by funds: $172M | Put options by funds: $50.2M

153% more first-time investments, than exits

New positions opened: 129 | Existing positions closed: 51

31% more capital invested

Capital invested by funds: $8.01B → $10.5B (+$2.48B)

25% more funds holding in top 10

Funds holding in top 10: 1215 (+3)

14% more funds holding

Funds holding: 502573 (+71)

1.41% more ownership

Funds ownership: 100.16%101.57% (+1.4%)

7% less repeat investments, than reductions

Existing positions increased: 180 | Existing positions reduced: 193

Holders
573
Holders Change
+71
Holders Change %
+14.14%
% of All Funds
6.97%
Holding in Top 10
15
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+25%
% of All Funds
0.18%
New
129
Increased
180
Reduced
193
Closed
51
Calls
$172M
Puts
$50.2M
Net Calls
+$122M
Net Calls Change
+$16.2M
Name Holding Trade Value Shares
Change
Change in
Stake
William Blair & Company
401
William Blair & Company
Illinois
$297K -$55.3K -361 -17%
MFS
402
Mirabella Financial Services
United Kingdom
$296K -$16.1K -105 -6%
SC
403
Syon Capital
California
$290K +$262K +1,708 New
MFF
404
Michels Family Financial
Texas
$290K -$3.83K -25 -1%
QCM
405
QRG Capital Management
Illinois
$288K +$260K +1,693 New
Acadian Asset Management
406
Acadian Asset Management
Massachusetts
$286K +$259K +1,687 New
PWPS
407
Pinnacle Wealth Planning Services
Ohio
$286K
AAM
408
Advisors Asset Management
Colorado
$280K -$143K -935 -36%
Jones Financial Companies
409
Jones Financial Companies
Missouri
$275K +$14.6K +95 +6%
TLCM
410
Twin Lakes Capital Management
California
$264K -$9.35K -61 -4%
OL
411
Optas LLC
Texas
$263K +$237K +1,547 New
GIP
412
Granite Investment Partners
California
$263K -$1.17M -7,630 -83%
DCM
413
DGS Capital Management
New Jersey
$260K +$235K +1,531 New
FCG
414
Fielder Capital Group
Tennessee
$260K +$234K +1,529 New
FPAS
415
Focus Partners Advisor Solutions
Missouri
$259K +$233K +1,521 New
PMAM
416
Picton Mahoney Asset Management
Ontario, Canada
$248K +$222K +1,450 +13,182%
BC
417
Bayforest Capital
United Kingdom
$247K -$42.9K -280 -16%
BAAM
418
Baker Avenue Asset Management
California
$244K +$220K +1,433 New
ECM
419
Everence Capital Management
Indiana
$243K +$219K +1,430 New
CB
420
Commerce Bank
Missouri
$242K +$218K +1,425 New
Cambridge Investment Research Advisors
421
Cambridge Investment Research Advisors
Iowa
$242K -$24.1K -157 -10%
SWP
422
Sagespring Wealth Partners
Tennessee
$240K +$216K +1,411 New
MYAM
423
Meiji Yasuda Asset Management
Japan
$240K +$216K +1,409 New
WI
424
Westbourne Investments
Virginia
$238K +$215K +1,400 New
SO
425
STRS Ohio
Ohio
$237K +$307 +2 +0.1%

JAZZ Hedge Fund Activity: Q4 2025 in Review

573 of the 8,224 institutional investors tracked by Wall St. Rank reported a position in Jazz Pharmaceuticals (JAZZ) for Q4 2025, worth a combined $10.5B — up 31% from $8.01B a quarter earlier.

Buyers outnumbered sellers: 129 funds opened new JAZZ positions and 51 closed out — a net gain of 78 holders — while 180 added to existing stakes and 193 trimmed.

The largest buyer was Franklin Resources, adding an estimated $173M. The largest seller was JP Morgan Chase, cutting an estimated $126M.

  • 573 institutional investors held Jazz Pharmaceuticals (JAZZ) as of Q4 2025, up from 502 in Q3 2025.
  • Funds reported $10.5B of Jazz Pharmaceuticals stock for Q4 2025, up 31% quarter-over-quarter.
  • 129 funds opened new Jazz Pharmaceuticals positions in Q4 2025 and 51 closed out, a net change of +78 holders.
  • The largest Jazz Pharmaceuticals buyer in Q4 2025 was Franklin Resources, an estimated $173M added.
  • The largest Jazz Pharmaceuticals seller in Q4 2025 was JP Morgan Chase, an estimated $126M sold.

Based on aggregated 13F filings for Q4 2025.