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Jazz Pharmaceuticals

573 hedge funds and large institutions have $10.5B invested in Jazz Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 129 funds opening new positions, 180 increasing their positions, 193 reducing their positions, and 51 closing their positions.

New
Increased
Maintained
Reduced
Closed

244% more call options, than puts

Call options by funds: $172M | Put options by funds: $50.2M

153% more first-time investments, than exits

New positions opened: 129 | Existing positions closed: 51

31% more capital invested

Capital invested by funds: $8.01B → $10.5B (+$2.48B)

25% more funds holding in top 10

Funds holding in top 10: 1215 (+3)

14% more funds holding

Funds holding: 502573 (+71)

1.41% more ownership

Funds ownership: 100.16%101.57% (+1.4%)

7% less repeat investments, than reductions

Existing positions increased: 180 | Existing positions reduced: 193

Holders
573
Holders Change
+71
Holders Change %
+14.14%
% of All Funds
6.97%
Holding in Top 10
15
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+25%
% of All Funds
0.18%
New
129
Increased
180
Reduced
193
Closed
51
Calls
$172M
Puts
$50.2M
Net Calls
+$122M
Net Calls Change
+$16.2M
Name Holding Trade Value Shares
Change
Change in
Stake
CL
351
Choreo LLC
Illinois
$492K +$442K +2,883 New
I
352
InceptionR
California
$489K +$441K +2,877 New
PA
353
Profund Advisors
Maryland
$488K -$124K -806 -22%
HT
354
Headlands Technologies
Illinois
$484K +$436K +2,846 New
MSRPS
355
Maryland State Retirement & Pension System
Maryland
$479K
GAM
356
Guinness Asset Management
United Kingdom
$475K -$78.5K -512 -16%
ECM
357
EMC Capital Management
Texas
$468K -$74.5K -486 -15%
EP
358
Edgestream Partners
New Jersey
$465K +$419K +2,733 New
AWM
359
AE Wealth Management
Kansas
$464K +$9.81K +64 +2%
MML Investors Services
360
MML Investors Services
Massachusetts
$450K -$465K -3,030 -53%
CIBC World Market
361
CIBC World Market
Ontario, Canada
$449K -$39.9K -260 -9%
ACM
362
Aquatic Capital Management
Illinois
$448K +$404K +2,636 New
P
363
&Partners
Tennessee
$448K -$298K -1,944 -42%
AWM
364
Affinity Wealth Management
Delaware
$447K
FFM
365
Forum Financial Management
Illinois
$443K
HAG
366
HighPoint Advisor Group
Illinois
$438K -$11K -72 -3%
GAM
367
Groupama Asset Management
France
$438K
LCM
368
Logan Capital Management
Pennsylvania
$437K
ECM
369
Evergreen Capital Management
Washington
$435K +$58.9K +384 +18%
PAG
370
Private Advisor Group
New Jersey
$434K -$30.2K -197 -7%
Rafferty Asset Management
371
Rafferty Asset Management
New York
$415K -$48K -313 -11%
Fifth Third Bancorp
372
Fifth Third Bancorp
Ohio
$413K +$4.6K +30 +1%
Vontobel Holding
373
Vontobel Holding
Switzerland
$411K +$60.3K +393 +19%
Two Sigma Investments
374
Two Sigma Investments
New York
$408K -$272K -1,773 -42%
TRCT
375
Tower Research Capital (TRC)
New York
$405K +$165K +1,073 +82%

JAZZ Hedge Fund Activity: Q4 2025 in Review

573 of the 8,224 institutional investors tracked by Wall St. Rank reported a position in Jazz Pharmaceuticals (JAZZ) for Q4 2025, worth a combined $10.5B — up 31% from $8.01B a quarter earlier.

Buyers outnumbered sellers: 129 funds opened new JAZZ positions and 51 closed out — a net gain of 78 holders — while 180 added to existing stakes and 193 trimmed.

The largest buyer was Franklin Resources, adding an estimated $173M. The largest seller was JP Morgan Chase, cutting an estimated $126M.

  • 573 institutional investors held Jazz Pharmaceuticals (JAZZ) as of Q4 2025, up from 502 in Q3 2025.
  • Funds reported $10.5B of Jazz Pharmaceuticals stock for Q4 2025, up 31% quarter-over-quarter.
  • 129 funds opened new Jazz Pharmaceuticals positions in Q4 2025 and 51 closed out, a net change of +78 holders.
  • The largest Jazz Pharmaceuticals buyer in Q4 2025 was Franklin Resources, an estimated $173M added.
  • The largest Jazz Pharmaceuticals seller in Q4 2025 was JP Morgan Chase, an estimated $126M sold.

Based on aggregated 13F filings for Q4 2025.