Invivyd
IVVD
116 hedge funds and large institutions have $594M invested in Invivyd in 2025 Q4 according to their latest regulatory filings, with 49 funds opening new positions, 27 increasing their positions, 18 reducing their positions, and 8 closing their positions.
513% more first-time investments, than exits
New positions opened: 49 | Existing positions closed: 8
262% more capital invested
Capital invested by funds: $164M → $594M (+$430M)
139% more call options, than puts
Call options by funds: $2.88M | Put options by funds: $1.21M
50% more repeat investments, than reductions
Existing positions increased: 27 | Existing positions reduced: 18
49% more funds holding
Funds holding: 78 → 116 (+38)
20.84% less ownership
Funds ownership: 123.86% → 103.02% (-21%)
50% less funds holding in top 10
Funds holding in top 10: 2 → 1 (-1)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
PA
Perceptive Advisors
New York
|
+$45.3M |
| 2 |
BI
BVF Inc
San Francisco,
California
|
+$40.6M |
| 3 |
SVCM
Saturn V Capital Management
Austin,
Texas
|
+$16.1M |
| 4 |
SCM
Soleus Capital Management
Greenwich,
Connecticut
|
+$16M |
| 5 |
Janus Henderson Group
London,
|
+$14.9M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Point72 Asset Management
Stamford,
Connecticut
|
-$7.59M |
| 2 |
ACM
ADAR1 Capital Management
Austin,
Texas
|
-$7.22M |
| 3 |
6CM
683 Capital Management
New York
|
-$7.07M |
| 4 |
GCP
GSA Capital Partners
London,
United Kingdom
|
-$891K |
| 5 |
Jane Street
New York
|
-$523K |
IVVD Hedge Fund Activity: Q4 2025 in Review
116 of the 8,270 institutional investors tracked by Wall St. Rank reported a position in Invivyd (IVVD) for Q4 2025, worth a combined $594M — up 262% from $164M a quarter earlier.
Buyers outnumbered sellers: 49 funds opened new IVVD positions and 8 closed out — a net gain of 41 holders — while 27 added to existing stakes and 18 trimmed.
The largest buyer was Perceptive Advisors, opening a new position worth an estimated $45.3M. The largest seller was Point72 Asset Management, cutting an estimated $7.59M.
- 116 institutional investors held Invivyd (IVVD) as of Q4 2025, up from 78 in Q3 2025.
- Funds reported $594M of Invivyd stock for Q4 2025, up 262% quarter-over-quarter.
- 49 funds opened new Invivyd positions in Q4 2025 and 8 closed out, a net change of +41 holders.
- The largest Invivyd buyer in Q4 2025 was Perceptive Advisors, an estimated $45.3M added.
- The largest Invivyd seller in Q4 2025 was Point72 Asset Management, an estimated $7.59M sold.
Based on aggregated 13F filings for Q4 2025.