|
1
|
RA Capital Management
Boston,
Massachusetts
|
$142M
|
–
|
–
|
–
|
|
|
2
|
|
$107M
|
+$62.4M
|
+1,718,085
|
+106%
|
|
|
3
|
Boxer Capital
San Diego,
California
|
$103M
|
-$41.9M
|
-1,152,958
|
-27%
|
|
|
4
|
MPM Asset Management
Boston,
Massachusetts
|
$88.1M
|
-$5.33M
|
-146,685
|
-5%
|
|
|
5
|
MPM BioImpact
Boston,
Massachusetts
|
$56.2M
|
-$3.59M
|
-98,784
|
-5%
|
|
|
6
|
State Street
Boston,
Massachusetts
|
$55.1M
|
+$34.5M
|
+948,540
|
+124%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$47.5M
|
+$15.1M
|
+415,232
|
+39%
|
|
|
8
|
BVF Inc
San Francisco,
California
|
$45.1M
|
+$50.9M
|
+1,400,201
|
New
|
|
|
9
|
AllianceBernstein
Nashville,
Tennessee
|
$36M
|
-$6.83M
|
-187,867
|
-14%
|
|
|
10
|
Tang Capital Management
San Diego,
California
|
$30.2M
|
–
|
–
|
–
|
|
|
11
|
Rubric Capital Management (New York)
New York
|
$26.5M
|
-$12.7M
|
-350,208
|
-30%
|
|
|
12
|
|
$25.8M
|
+$23.2M
|
+638,371
|
+389%
|
|
|
13
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$22M
|
-$2.67M
|
-73,515
|
-10%
|
|
|
14
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$22M
|
+$24.4M
|
+670,533
|
+5,465%
|
|
|
15
|
Fidelity Investments
Boston,
Massachusetts
|
$19.7M
|
-$6.61M
|
-181,944
|
-23%
|
|
|
16
|
Citadel Advisors
Miami,
Florida
|
$16.8M
|
-$17.3M
|
-477,470
|
-48%
|
|
|
17
|
|
$15.7M
|
-$67.7M
|
-1,864,001
|
-79%
|
|
|
18
|
Octagon Capital Advisors
New York
|
$14.5M
|
–
|
–
|
–
|
|
|
19
|
Pacer Advisors
Malvern,
Pennsylvania
|
$14.3M
|
+$16.1M
|
+443,460
|
New
|
|
|
20
|
Gotham Asset Management
New York
|
$13.7M
|
+$5.13M
|
+141,165
|
New
|
|
|
21
|
|
$12.9M
|
-$5.23M
|
-144,047
|
-26%
|
|
|
22
|
Geode Capital Management
Boston,
Massachusetts
|
$12.9M
|
+$932K
|
+25,662
|
+7%
|
|
|
23
|
Millennium Management
New York
|
$8.85M
|
+$1.72M
|
+47,424
|
+21%
|
|
|
24
|
Sectoral Asset Management
Montreal,
Quebec, Canada
|
$7.54M
|
+$5.6M
|
+154,150
|
+193%
|
|
|
25
|
Two Sigma Advisers
New York
|
$7.44M
|
+$1.86M
|
+51,100
|
+28%
|
|
