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ITOS

iTeos Therapeutics

Delisted

ITOS was delisted on the 28th of August, 2025.

118 hedge funds and large institutions have $1.55B invested in iTeos Therapeutics in 2021 Q4 according to their latest regulatory filings, with 46 funds opening new positions, 37 increasing their positions, 24 reducing their positions, and 4 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,050% more first-time investments, than exits

New positions opened: 46 | Existing positions closed: 4

85% more capital invested

Capital invested by funds: $841M → $1.55B (+$712M)

75% more funds holding in top 10

Funds holding in top 10: 47 (+3)

54% more repeat investments, than reductions

Existing positions increased: 37 | Existing positions reduced: 24

53% more funds holding

Funds holding: 77118 (+41)

6.23% more ownership

Funds ownership: 88.47%94.71% (+6.2%)

Holders
118
Holders Change
+41
Holders Change %
+53.25%
% of All Funds
1.82%
Holding in Top 10
7
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+75%
% of All Funds
0.11%
New
46
Increased
37
Reduced
24
Closed
4
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
RCM
1
RA Capital Management
Massachusetts
$206M
BC
2
Boxer Capital
California
$202M
MAM
3
MPM Asset Management
Massachusetts
$134M -$13.5M -405,241 -12%
RI
4
RTW Investments
New York
$110M
MB
5
MPM BioImpact
Massachusetts
$85.9M -$8.73M -262,365 -12%
BlackRock
6
BlackRock
New York
$75.1M +$1.83M +54,992 +4%
AllianceBernstein
7
AllianceBernstein
Tennessee
$60.8M -$994K -29,868 -2%
EC
8
EcoR1 Capital
California
$60.7M
RCMNY
9
Rubric Capital Management (New York)
New York
$54.6M +$6.11M +183,637 +19%
Vanguard Group
10
Vanguard Group
Pennsylvania
$49.4M +$14.7M +441,779 +71%
Citadel Advisors
11
Citadel Advisors
Florida
$46.5M +$783K +23,523 +2%
TCM
12
Tang Capital Management
California
$43.6M +$1.25M +37,500 +4%
Fidelity Investments
13
Fidelity Investments
Massachusetts
$37M -$320K -9,600 -1%
State Street
14
State Street
Massachusetts
$35.5M +$14.7M +441,244 +137%
CS
15
Candriam SCA
Luxembourg
$35.3M +$7.73M +232,083 +44%
AG
16
Artal Group
Luxembourg
$25.3M -$15M -450,000 -45%
OCA
17
Octagon Capital Advisors
New York
$21M +$15M +450,776 New
Geode Capital Management
18
Geode Capital Management
Massachusetts
$17.4M +$880K +26,425 +8%
Millennium Management
19
Millennium Management
New York
$10.6M +$7.57M +227,436 New
Axa
20
Axa
France
$10.2M +$87K +2,614 +1%
Marshall Wace
21
Marshall Wace
United Kingdom
$10.1M +$5.33M +160,265 +283%
Citigroup
22
Citigroup
New York
$9.71M -$6.82M -204,972 -50%
Two Sigma Investments
23
Two Sigma Investments
New York
$9.66M +$1.32M +39,613 +24%
Northern Trust
24
Northern Trust
Illinois
$8.64M +$306K +9,188 +5%
Two Sigma Advisers
25
Two Sigma Advisers
New York
$8.38M +$2.08M +62,400 +53%

ITOS Hedge Fund Activity: Q4 2021 in Review

118 of the 6,498 institutional investors tracked by Wall St. Rank reported a position in iTeos Therapeutics (ITOS) for Q4 2021, worth a combined $1.55B — up 85% from $841M a quarter earlier.

Buyers outnumbered sellers: 46 funds opened new ITOS positions and 4 closed out — a net gain of 42 holders — while 37 added to existing stakes and 24 trimmed.

The largest buyer was Octagon Capital Advisors, opening a new position worth an estimated $15M. The largest seller was Artal Group, cutting an estimated $15M.

  • 118 institutional investors held iTeos Therapeutics (ITOS) as of Q4 2021, up from 77 in Q3 2021.
  • Funds reported $1.55B of iTeos Therapeutics stock for Q4 2021, up 85% quarter-over-quarter.
  • 46 funds opened new iTeos Therapeutics positions in Q4 2021 and 4 closed out, a net change of +42 holders.
  • The largest iTeos Therapeutics buyer in Q4 2021 was Octagon Capital Advisors, an estimated $15M added.
  • The largest iTeos Therapeutics seller in Q4 2021 was Artal Group, an estimated $15M sold.

Based on aggregated 13F filings for Q4 2021.