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ITOS

iTeos Therapeutics
ITOS

Delisted

ITOS was delisted on the 28th of August, 2025.

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118 hedge funds and large institutions have $1.55B invested in iTeos Therapeutics in 2021 Q4 according to their latest regulatory filings, with 46 funds opening new positions, 37 increasing their positions, 24 reducing their positions, and 4 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,050% more first-time investments, than exits

New positions opened: 46 | Existing positions closed: 4

85% more capital invested

Capital invested by funds: $841M → $1.55B (+$712M)

75% more funds holding in top 10

Funds holding in top 10: 4 → 7 (+3)

54% more repeat investments, than reductions

Existing positions increased: 37 | Existing positions reduced: 24

53% more funds holding

Funds holding: 77 → 118 (+41)

6.23% more ownership

Funds ownership: 88.47% → 94.71% (+6.2%)

Holders
118
Holders Change
+41
Holders Change %
+53.25%
% of All Funds
1.82%
Holding in Top 10
7
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+75%
% of All Funds
0.11%
New
46
Increased
37
Reduced
24
Closed
4
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

Rank Fund Capital Flow
1
OCA
Octagon Capital Advisors
New York
+$15M
2
Vanguard Group
Vanguard Group
Pennsylvania
+$14.7M
3
State Street
State Street
Massachusetts
+$14.7M
4
CS
Candriam SCA
Luxembourg
+$7.73M
5
Millennium Management
Millennium Management
New York
+$7.57M

Top Sellers

Rank Fund Capital Flow
1
AG
Artal Group
Luxembourg
-$15M
2
MAM
MPM Asset Management
Massachusetts
-$13.5M
3
MB
MPM BioImpact
Massachusetts
-$8.73M
4
Citigroup
Citigroup
New York
-$6.82M
5
SAM
Sectoral Asset Management
Quebec, Canada
-$6.45M
Name Holding Trade Value Shares
Change 		Change in
Stake
CCM
76
Cinctive Capital Management
New York
$987K +$706K +21,200 New
PA
77
Perceptive Advisors
New York
$931K +$666K +20,000 New
Man Group
78
Man Group
United Kingdom
$913K -$243K -7,301 -27%
SFI
79
Susquehanna Fundamental Investments
Pennsylvania
$889K +$267K +8,010 +72%
SEI Investments
80
SEI Investments
Pennsylvania
$830K +$593K +17,819 New
AIMCA
81
Alberta Investment Management Corp (AIMCo)
Alberta, Canada
$781K +$558K +16,777 New
AA
82
AlphaCentric Advisors
Puerto Rico
$698K +$499K +15,000 New
Jane Street
83
Jane Street
New York
$692K +$494K +14,853 New
FLC
84
Fifth Lane Capital
Texas
$678K +$485K +14,566 New
New York State Common Retirement Fund
85
New York State Common Retirement Fund
New York
$655K -$1.4K -42 -0.3%
CF
86
CNA Financial
Illinois
$585K -$48.3K -1,450 -10%
Deutsche Bank
87
Deutsche Bank
Germany
$571K -$1.93M -57,898 -83%
CS
88
Credit Suisse
Switzerland
$535K +$383K +11,502 New
AIG
89
American International Group
New York
$500K -$10.7K -321 -3%
DU
90
Delphia (USA)
Ontario, Canada
$495K +$354K +10,631 New
DekaBank Deutsche Girozentrale
91
DekaBank Deutsche Girozentrale
Germany
$475K +$9.99K +300 +3%
ProShare Advisors
92
ProShare Advisors
Maryland
$437K -$24.2K -728 -7%
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
93
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$400K -$3.45M -103,700 -92%
Wells Fargo
94
Wells Fargo
California
$390K -$1.72M -51,544 -86%
MIM
95
MetLife Investment Management
New Jersey
$372K – – –
VOYA Investment Management
96
VOYA Investment Management
Georgia
$372K -$10.3K -308 -4%
Acadian Asset Management
97
Acadian Asset Management
Massachusetts
$347K +$250K +7,497 New
SG Americas Securities
98
SG Americas Securities
New York
$324K -$242K -7,265 -51%
Verition Fund Management
99
Verition Fund Management
Connecticut
$300K +$214K +6,435 New
Zurich Cantonal Bank
100
Zurich Cantonal Bank
Switzerland
$283K +$144K +4,322 +246%
1 2 3
4
5

ITOS Hedge Fund Activity: Q4 2021 in Review

118 of the 6,498 institutional investors tracked by Wall St. Rank reported a position in iTeos Therapeutics (ITOS) for Q4 2021, worth a combined $1.55B — up 85% from $841M a quarter earlier.

Buyers outnumbered sellers: 46 funds opened new ITOS positions and 4 closed out — a net gain of 42 holders — while 37 added to existing stakes and 24 trimmed.

The largest buyer was Octagon Capital Advisors, opening a new position worth an estimated $15M. The largest seller was Artal Group, cutting an estimated $15M.

  • 118 institutional investors held iTeos Therapeutics (ITOS) as of Q4 2021, up from 77 in Q3 2021.
  • Funds reported $1.55B of iTeos Therapeutics stock for Q4 2021, up 85% quarter-over-quarter.
  • 46 funds opened new iTeos Therapeutics positions in Q4 2021 and 4 closed out, a net change of +42 holders.
  • The largest iTeos Therapeutics buyer in Q4 2021 was Octagon Capital Advisors, an estimated $15M added.
  • The largest iTeos Therapeutics seller in Q4 2021 was Artal Group, an estimated $15M sold.

Based on aggregated 13F filings for Q4 2021.