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ITOS

iTeos Therapeutics
ITOS

Delisted

ITOS was delisted on the 28th of August, 2025.

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118 hedge funds and large institutions have $1.55B invested in iTeos Therapeutics in 2021 Q4 according to their latest regulatory filings, with 46 funds opening new positions, 37 increasing their positions, 24 reducing their positions, and 4 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,050% more first-time investments, than exits

New positions opened: 46 | Existing positions closed: 4

85% more capital invested

Capital invested by funds: $841M → $1.55B (+$712M)

75% more funds holding in top 10

Funds holding in top 10: 4 → 7 (+3)

54% more repeat investments, than reductions

Existing positions increased: 37 | Existing positions reduced: 24

53% more funds holding

Funds holding: 77 → 118 (+41)

6.23% more ownership

Funds ownership: 88.47% → 94.71% (+6.2%)

Holders
118
Holders Change
+41
Holders Change %
+53.25%
% of All Funds
1.82%
Holding in Top 10
7
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+75%
% of All Funds
0.11%
New
46
Increased
37
Reduced
24
Closed
4
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

Rank Fund Capital Flow
1
OCA
Octagon Capital Advisors
New York
+$15M
2
Vanguard Group
Vanguard Group
Pennsylvania
+$14.7M
3
State Street
State Street
Massachusetts
+$14.7M
4
CS
Candriam SCA
Luxembourg
+$7.73M
5
Millennium Management
Millennium Management
New York
+$7.57M

Top Sellers

Rank Fund Capital Flow
1
AG
Artal Group
Luxembourg
-$15M
2
MAM
MPM Asset Management
Massachusetts
-$13.5M
3
MB
MPM BioImpact
Massachusetts
-$8.73M
4
Citigroup
Citigroup
New York
-$6.82M
5
SAM
Sectoral Asset Management
Quebec, Canada
-$6.45M
Name Holding Trade Value Shares
Change 		Change in
Stake
CSS
51
Cubist Systematic Strategies
Connecticut
$2.49M +$1.41M +42,323 +378%
Norges Bank
52
Norges Bank
Norway
$2.44M +$1.75M +52,500 New
IHAM
53
Integral Health Asset Management
New York
$2.33M +$1.66M +50,000 New
American Century Companies
54
American Century Companies
Missouri
$2.25M +$1.6M +48,208 New
Invesco
55
Invesco
Georgia
$2.19M +$1.31M +39,223 +506%
Jacobs Levy Equity Management
56
Jacobs Levy Equity Management
New Jersey
$2.12M +$1.52M +45,551 New
EGI
57
EAM Global Investors
California
$2.02M +$1.45M +43,493 New
TCM
58
Tekla Capital Management
Massachusetts
$1.97M – – –
PI
59
Putnam Investments
Massachusetts
$1.97M +$1.41M +42,309 New
JF
60
Jump Financial
Illinois
$1.95M +$1.39M +41,900 New
Rafferty Asset Management
61
Rafferty Asset Management
New York
$1.88M +$1.34M +40,316 New
JCIA
62
Jackson Creek Investment Advisors
Colorado
$1.77M +$1.26M +37,994 New
UBS Group
63
UBS Group
Switzerland
$1.76M +$1.25M +37,621 +27,867%
HS
64
HighVista Strategies
Massachusetts
$1.61M +$1.15M +34,487 New
Walleye Capital
65
Walleye Capital
New York
$1.59M +$1.14M +34,253 New
Renaissance Technologies
66
Renaissance Technologies
New York
$1.54M +$1.1M +33,100 New
Swiss National Bank
67
Swiss National Bank
Switzerland
$1.44M +$1.03M +31,000 New
CC
68
Corton Capital
Ontario, Canada
$1.27M +$911K +27,377 New
RhumbLine Advisers
69
RhumbLine Advisers
Massachusetts
$1.27M +$16.8K +504 +2%
State of Wisconsin Investment Board
70
State of Wisconsin Investment Board
Wisconsin
$1.25M +$396K +11,900 +79%
Massachusetts Financial Services
71
Massachusetts Financial Services
Massachusetts
$1.16M +$827K +24,829 New
VIA
72
Vident Investment Advisory
Georgia
$1.13M +$804K +24,153 New
JMPWA
73
JP Morgan Private Wealth Advisors
California
$1.1M +$786K +23,617 New
California State Teachers Retirement System (CalSTRS)
74
California State Teachers Retirement System (CalSTRS)
California
$1.06M +$396K +11,894 +109%
SO
75
STRS Ohio
Ohio
$1.06M +$393K +11,800 +108%
1 2
3
4 5

ITOS Hedge Fund Activity: Q4 2021 in Review

118 of the 6,498 institutional investors tracked by Wall St. Rank reported a position in iTeos Therapeutics (ITOS) for Q4 2021, worth a combined $1.55B — up 85% from $841M a quarter earlier.

Buyers outnumbered sellers: 46 funds opened new ITOS positions and 4 closed out — a net gain of 42 holders — while 37 added to existing stakes and 24 trimmed.

The largest buyer was Octagon Capital Advisors, opening a new position worth an estimated $15M. The largest seller was Artal Group, cutting an estimated $15M.

  • 118 institutional investors held iTeos Therapeutics (ITOS) as of Q4 2021, up from 77 in Q3 2021.
  • Funds reported $1.55B of iTeos Therapeutics stock for Q4 2021, up 85% quarter-over-quarter.
  • 46 funds opened new iTeos Therapeutics positions in Q4 2021 and 4 closed out, a net change of +42 holders.
  • The largest iTeos Therapeutics buyer in Q4 2021 was Octagon Capital Advisors, an estimated $15M added.
  • The largest iTeos Therapeutics seller in Q4 2021 was Artal Group, an estimated $15M sold.

Based on aggregated 13F filings for Q4 2021.