Intuitive Surgical
ISRG
2,110 hedge funds and large institutions have $130B invested in Intuitive Surgical in 2025 Q3 according to their latest regulatory filings, with 147 funds opening new positions, 848 increasing their positions, 811 reducing their positions, and 266 closing their positions.
5% more repeat investments, than reductions
Existing positions increased: 848 | Existing positions reduced: 811
3.6% less ownership
Funds ownership: 85.39% → 81.8% (-3.6%)
7% less funds holding
Funds holding: 2,265 → 2,110 (-155)
22% less capital invested
Capital invested by funds: $168B → $130B (-$37.2B)
26% less call options, than puts
Call options by funds: $1.39B | Put options by funds: $1.87B
28% less funds holding in top 10
Funds holding in top 10: 68 → 49 (-19)
45% less first-time investments, than exits
New positions opened: 147 | Existing positions closed: 266
Top Buyers
| 1 |
D.E. Shaw & Co
New York
|
+$666M |
| 2 |
Amundi
Paris,
France
|
+$355M |
| 3 |
Two Sigma Advisers
New York
|
+$335M |
| 4 |
Jane Street
New York
|
+$320M |
| 5 |
Qube Research & Technologies (QRT)
London,
United Kingdom
|
+$296M |
Top Sellers
ISRG Hedge Fund Activity: Q3 2025 in Review
2,110 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Intuitive Surgical (ISRG) for Q3 2025, worth a combined $130B — down 22% from $168B a quarter earlier.
Sellers outnumbered buyers: 266 funds closed out of ISRG and 147 opened new positions — a net loss of 119 holders — while 811 trimmed existing stakes and 848 added.
The largest buyer was D.E. Shaw & Co, adding an estimated $666M. The largest seller was JP Morgan Chase, cutting an estimated $2B.
- 2,110 institutional investors held Intuitive Surgical (ISRG) as of Q3 2025, down from 2,265 in Q2 2025.
- Funds reported $130B of Intuitive Surgical stock for Q3 2025, down 22% quarter-over-quarter.
- 147 funds opened new Intuitive Surgical positions in Q3 2025 and 266 closed out, a net change of -119 holders.
- The largest Intuitive Surgical buyer in Q3 2025 was D.E. Shaw & Co, an estimated $666M added.
- The largest Intuitive Surgical seller in Q3 2025 was JP Morgan Chase, an estimated $2B sold.
Based on aggregated 13F filings for Q3 2025.