iSpecimen
ISPC
9 hedge funds and large institutions have $32.9K invested in iSpecimen in 2025 Q4 according to their latest regulatory filings, with 3 funds opening new positions, 2 increasing their positions, 2 reducing their positions, and 4 closing their positions.
0% more repeat investments, than reductions
Existing positions increased: 2 | Existing positions reduced: 2
0.12% less ownership
Funds ownership: 0.15% → 0.03% (-0.12%)
10% less funds holding
Funds holding: 10 → 9 (-1)
25% less first-time investments, than exits
New positions opened: 3 | Existing positions closed: 4
93% less capital invested
Capital invested by funds: $443K → $32.9K (-$410K)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
|
+$9.55K |
| 2 |
JF
Jump Financial
Chicago,
Illinois
|
+$6.64K |
| 3 |
UBS Group
Zurich,
Switzerland
|
+$4.08K |
| 4 |
TRCT
Tower Research Capital (TRC)
New York
|
+$2.74K |
| 5 |
Bank of America
Charlotte,
North Carolina
|
+$25 |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Renaissance Technologies
New York
|
-$198K |
| 2 |
VF
Virtu Financial
New York
|
-$82K |
| 3 |
SRL
Scientech Research LLC
Jersey City,
New Jersey
|
-$38K |
| 4 |
Jane Street
New York
|
-$3.9K |
| 5 |
Fidelity Investments
Boston,
Massachusetts
|
-$387 |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
1
Geode Capital Management
Boston,
Massachusetts
| $10.8K | -$51 | -2 | -0.2% |
|
2
Vanguard Group
Malvern,
Pennsylvania
| $7.65K | – | – | – |
|
|
3
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
| $3.92K | +$9.55K | +377 | New |
|
|
4
Jane Street
New York
| $3.67K | -$3.9K | -154 | -30% |
|
|
JF
5
Jump Financial
Chicago,
Illinois
| $2.72K | +$6.64K | +262 | New |
|
|
TRCT
6
Tower Research Capital (TRC)
New York
| $1.73K | +$2.74K | +108 | +183% |
|
|
7
UBS Group
Zurich,
Switzerland
| $1.68K | +$4.08K | +161 | New |
|
8
BlackRock
New York
| $735 | – | – | – |
|
|
9
Bank of America
Charlotte,
North Carolina
| $22 | +$25 | +1 | +100% |
|
|
S
10
Sachetta
Lynnfield,
Massachusetts
| $1 | – | – | – |
|
|
SS
11
SBI Securities
Tokyo,
Japan
| $1 | – | – | – |
|
|
12
Renaissance Technologies
New York
| – | -$198K | -3,836 | Closed |
|
|
VF
13
Virtu Financial
New York
| – | -$82K | -1,581 | Closed |
|
|
SRL
14
Scientech Research LLC
Jersey City,
New Jersey
| – | -$38K | -737 | Closed |
|
|
15
Fidelity Investments
Boston,
Massachusetts
| – | -$387 | -8 | Closed |
|
ISPC Hedge Fund Activity: Q4 2025 in Review
9 of the 8,228 institutional investors tracked by Wall St. Rank reported a position in iSpecimen (ISPC) for Q4 2025, worth a combined $32.9K — down 93% from $443K a quarter earlier.
Sellers outnumbered buyers: 4 funds closed out of ISPC and 3 opened new positions — a net loss of 1 holder — while 2 trimmed existing stakes and 2 added.
The largest buyer was Susquehanna International Group, opening a new position worth an estimated $9.55K. The largest seller was Renaissance Technologies, exiting entirely with an estimated $198K sold.
- 9 institutional investors held iSpecimen (ISPC) as of Q4 2025, down from 10 in Q3 2025.
- Funds reported $32.9K of iSpecimen stock for Q4 2025, down 93% quarter-over-quarter.
- 3 funds opened new iSpecimen positions in Q4 2025 and 4 closed out, a net change of -1 holder.
- The largest iSpecimen buyer in Q4 2025 was Susquehanna International Group, an estimated $9.55K added.
- The largest iSpecimen seller in Q4 2025 was Renaissance Technologies, an estimated $198K sold.
Based on aggregated 13F filings for Q4 2025.