iRhythm Holdings
IRTC
334 hedge funds and large institutions have $6.24B invested in iRhythm Holdings in 2025 Q4 according to their latest regulatory filings, with 46 funds opening new positions, 108 increasing their positions, 122 reducing their positions, and 43 closing their positions.
15% more capital inflows, than outflows
Capital inflows: $839M | Capital outflows: $729M
1.13% more ownership
Funds ownership: 108.02% → 109.16% (+1.1%)
7% more first-time investments, than exits
New positions opened: 46 | Existing positions closed: 43
0% more funds holding in top 10
Funds holding in top 10: 2 → 2 (0)
1% less funds holding
Funds holding: 338 → 334 (-4)
11% less repeat investments, than reductions
Existing positions increased: 108 | Existing positions reduced: 122
67% less call options, than puts
Call options by funds: $7M | Put options by funds: $21.3M
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
RTW Investments
New York
|
+$209M |
| 2 |
Millennium Management
New York
|
+$97.2M |
| 3 |
JP Morgan Chase
New York
|
+$56.6M |
| 4 |
UBS AM
Chicago,
Illinois
|
+$46M |
| 5 |
Holocene Advisors
New York
|
+$37.3M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Artisan Partners
Milwaukee,
Wisconsin
|
-$187M |
| 2 |
Sands Capital Management
Arlington,
Virginia
|
-$95.1M |
| 3 |
CIP
Champlain Investment Partners
Burlington,
Vermont
|
-$62.9M |
| 4 |
Man Group
London,
United Kingdom
|
-$26.6M |
| 5 |
Point72 Asset Management
Stamford,
Connecticut
|
-$22.8M |
IRTC Hedge Fund Activity: Q4 2025 in Review
334 of the 8,288 institutional investors tracked by Wall St. Rank reported a position in iRhythm Holdings (IRTC) for Q4 2025, worth a combined $6.24B — up 4.6% from $5.97B a quarter earlier.
Buyers outnumbered sellers: 46 funds opened new IRTC positions and 43 closed out — a net gain of 3 holders — while 108 added to existing stakes and 122 trimmed.
The largest buyer was RTW Investments, opening a new position worth an estimated $209M. The largest seller was Artisan Partners, cutting an estimated $187M.
- 334 institutional investors held iRhythm Holdings (IRTC) as of Q4 2025, down from 338 in Q3 2025.
- Funds reported $6.24B of iRhythm Holdings stock for Q4 2025, up 4.6% quarter-over-quarter.
- 46 funds opened new iRhythm Holdings positions in Q4 2025 and 43 closed out, a net change of +3 holders.
- The largest iRhythm Holdings buyer in Q4 2025 was RTW Investments, an estimated $209M added.
- The largest iRhythm Holdings seller in Q4 2025 was Artisan Partners, an estimated $187M sold.
Based on aggregated 13F filings for Q4 2025.