|
1
|
NEA Management Company
Timonium,
Maryland
|
$48.4M
|
–
|
–
|
–
|
|
|
2
|
Sofinnova Investments
Menlo Park,
California
|
$40.2M
|
–
|
–
|
–
|
|
|
3
|
RA Capital Management
Boston,
Massachusetts
|
$39.7M
|
–
|
–
|
–
|
|
|
4
|
Novo Holdings A/S
Hellerup,
Denmark
|
$39M
|
-$13.2M
|
-600,000
|
-23%
|
|
|
5
|
Deerfield Management
New York
|
$38.9M
|
+$18M
|
+813,701
|
+71%
|
|
|
6
|
Pivotal bioVenture Partners Investment Advisor
San Francisco,
California
|
$31.5M
|
–
|
–
|
–
|
|
|
7
|
Adage Capital Partners
Boston,
Massachusetts
|
$21.6M
|
+$4.26M
|
+193,000
|
+22%
|
|
|
8
|
|
$18.4M
|
-$1.5M
|
-68,132
|
-7%
|
|
|
9
|
|
$17.1M
|
+$5.1M
|
+230,932
|
+37%
|
|
|
10
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$16.4M
|
-$58.4K
|
-2,646
|
-0.3%
|
|
|
11
|
Fidelity Investments
Boston,
Massachusetts
|
$12.1M
|
–
|
–
|
–
|
|
|
12
|
Wellington Management Group
Boston,
Massachusetts
|
$9.26M
|
+$638K
|
+28,914
|
+7%
|
|
|
13
|
Suvretta Capital Management
New York
|
$6.76M
|
+$2.8M
|
+127,116
|
+59%
|
|
|
14
|
Vanguard Group
Malvern,
Pennsylvania
|
$6.75M
|
+$703K
|
+31,850
|
+10%
|
|
|
15
|
Citadel Advisors
Miami,
Florida
|
$4.76M
|
-$268K
|
-12,141
|
-5%
|
|
|
16
|
CAAS Capital Management
New York
|
$3.52M
|
+$3.92M
|
+177,502
|
New
|
|
|
17
|
Burrage Capital Management
Boston,
Massachusetts
|
$3.36M
|
-$29.2K
|
-1,323
|
-0.8%
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
$2.98M
|
+$969K
|
+43,915
|
+41%
|
|
|
19
|
Millennium Management
New York
|
$2.95M
|
+$3.29M
|
+149,205
|
New
|
|
|
20
|
State Street
Boston,
Massachusetts
|
$2.62M
|
+$323K
|
+14,640
|
+12%
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
$2.29M
|
+$500K
|
+22,663
|
+24%
|
|
|
22
|
Baker Bros. Advisors
New York
|
$2.12M
|
–
|
–
|
–
|
|
|
23
|
Commonwealth Equity Services
Waltham,
Massachusetts
|
$1.3M
|
+$1.45M
|
+65,781
|
New
|
|
|
24
|
Charles Schwab
San Francisco,
California
|
$1.18M
|
+$231K
|
+10,450
|
+21%
|
|
|
25
|
Marshall Wace
London,
United Kingdom
|
$1.03M
|
+$1.14M
|
+51,813
|
New
|
|
