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Inspire Medical Systems

342 hedge funds and large institutions have $3.12B invested in Inspire Medical Systems in 2025 Q4 according to their latest regulatory filings, with 92 funds opening new positions, 114 increasing their positions, 114 reducing their positions, and 69 closing their positions.

New
Increased
Maintained
Reduced
Closed

35% more capital invested

Capital invested by funds: $2.31B → $3.12B (+$816M)

33% more first-time investments, than exits

New positions opened: 92 | Existing positions closed: 69

11.46% more ownership

Funds ownership: 105.16%116.62% (+11%)

5% more funds holding

Funds holding: 325342 (+17)

0% more repeat investments, than reductions

Existing positions increased: 114 | Existing positions reduced: 114

11% less call options, than puts

Call options by funds: $41.8M | Put options by funds: $47.2M

100% less funds holding in top 10

Funds holding in top 10: 10 (-1)

Holders
342
Holders Change
+17
Holders Change %
+5.23%
% of All Funds
4.16%
Holding in Top 10
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
New
92
Increased
114
Reduced
114
Closed
69
Calls
$41.8M
Puts
$47.2M
Net Calls
-$5.34M
Net Calls Change
+$5M
Name Holding Trade Value Shares
Change
Change in
Stake
BlackRock
1
BlackRock
New York
$327M +$350K +3,653 +0.1%
Vanguard Group
2
Vanguard Group
Pennsylvania
$272M -$4.49M -46,917 -2%
Wellington Management Group
3
Wellington Management Group
Massachusetts
$204M +$212M +2,211,091 New
DM
4
Deerfield Management
New York
$139M +$43.8M +458,178 +44%
Morgan Stanley
5
Morgan Stanley
New York
$116M +$77.4M +809,121 +180%
D.E. Shaw & Co
6
D.E. Shaw & Co
New York
$112M +$81.6M +853,305 +238%
William Blair Investment Management
7
William Blair Investment Management
Illinois
$107M -$13M -136,288 -11%
State Street
8
State Street
Massachusetts
$84.7M -$5.82M -60,805 -6%
Artisan Partners
9
Artisan Partners
Wisconsin
$72.5M +$24.8M +259,500 +49%
Fuller & Thaler Asset Management
10
Fuller & Thaler Asset Management
California
$61.6M +$63.9M +668,099 New
Janus Henderson Group
11
Janus Henderson Group
United Kingdom
$51.9M -$10M -104,747 -16%
B
12
Braidwell
Connecticut
$49.9M -$32.8M -342,857 -39%
Marshall Wace
13
Marshall Wace
United Kingdom
$49M +$38M +396,810 +296%
Deutsche Bank
14
Deutsche Bank
Germany
$47.7M +$48.8M +509,628 +7,090%
Citadel Advisors
15
Citadel Advisors
Florida
$47.2M -$118M -1,237,091 -71%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$45.4M -$1.27M -13,237 -3%
UBS AM
17
UBS AM
Illinois
$42.7M -$35.4M -370,283 -44%
Aberdeen Group
18
Aberdeen Group
United Kingdom
$42.5M +$6.18M +64,561 +16%
BNP Paribas Financial Markets
19
BNP Paribas Financial Markets
France
$41.9M -$6.45M -67,370 -13%
EAM
20
Eventide Asset Management
Massachusetts
$40.6M +$17.6M +183,547 +72%
UBS Group
21
UBS Group
Switzerland
$37.9M -$5.4M -56,407 -12%
Renaissance Technologies
22
Renaissance Technologies
New York
$37.9M +$24.5M +255,768 +165%
Amundi
23
Amundi
France
$33.6M +$10.5M +109,498 +43%
DCM
24
Driehaus Capital Management
Illinois
$32.1M +$33.3M +348,500 New
Dimensional Fund Advisors
25
Dimensional Fund Advisors
Texas
$31.5M -$222K -2,321 -0.7%

INSP Hedge Fund Activity: Q4 2025 in Review

342 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Inspire Medical Systems (INSP) for Q4 2025, worth a combined $3.12B — up 35% from $2.31B a quarter earlier.

Buyers outnumbered sellers: 92 funds opened new INSP positions and 69 closed out — a net gain of 23 holders — while 114 added to existing stakes and 114 trimmed.

The largest buyer was Wellington Management Group, opening a new position worth an estimated $212M. The largest seller was Citadel Advisors, cutting an estimated $118M.

  • 342 institutional investors held Inspire Medical Systems (INSP) as of Q4 2025, up from 325 in Q3 2025.
  • Funds reported $3.12B of Inspire Medical Systems stock for Q4 2025, up 35% quarter-over-quarter.
  • 92 funds opened new Inspire Medical Systems positions in Q4 2025 and 69 closed out, a net change of +23 holders.
  • The largest Inspire Medical Systems buyer in Q4 2025 was Wellington Management Group, an estimated $212M added.
  • The largest Inspire Medical Systems seller in Q4 2025 was Citadel Advisors, an estimated $118M sold.

Based on aggregated 13F filings for Q4 2025.