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Inovio Pharmaceuticals

102 hedge funds and large institutions have $57.5M invested in Inovio Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 21 funds opening new positions, 25 increasing their positions, 22 reducing their positions, and 18 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,161% more call options, than puts

Call options by funds: $2.02M | Put options by funds: $160K

19% more capital invested

Capital invested by funds: $48.4M → $57.5M (+$9.01M)

17% more first-time investments, than exits

New positions opened: 21 | Existing positions closed: 18

14% more repeat investments, than reductions

Existing positions increased: 25 | Existing positions reduced: 22

9.1% more ownership

Funds ownership: 38.97%48.07% (+9.1%)

3% more funds holding

Funds holding: 99102 (+3)

Holders
102
Holders Change
+3
Holders Change %
+3.03%
% of All Funds
1.24%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
21
Increased
25
Reduced
22
Closed
18
Calls
$2.02M
Puts
$160K
Net Calls
+$1.86M
Net Calls Change
-$535K
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$17.1M +$21.7M +9,845,363 +756,753%
Janus Henderson Group
2
Janus Henderson Group
United Kingdom
$5.77M +$92.8K +42,146 +1%
Vanguard Group
3
Vanguard Group
Pennsylvania
$5.77M +$1.33M +602,708 +22%
Adage Capital Partners
4
Adage Capital Partners
Massachusetts
$4.44M -$1.93M -875,000 -26%
BCM
5
Boxer Capital Management
California
$4.21M +$265K +120,122 +5%
D.E. Shaw & Co
6
D.E. Shaw & Co
New York
$3.88M +$3.14M +1,425,069 +177%
ACM
7
ADAR1 Capital Management
Texas
$2.58M +$3.27M +1,485,008 New
Millennium Management
8
Millennium Management
New York
$2.44M -$1.25M -569,139 -29%
Geode Capital Management
9
Geode Capital Management
Massachusetts
$1.34M +$490K +222,609 +41%
BlackRock
10
BlackRock
New York
$1.08M +$261K +118,466 +24%
Renaissance Technologies
11
Renaissance Technologies
New York
$963K -$580K -263,175 -32%
DP
12
Diadema Partners
New Jersey
$929K +$1.18M +533,682 New
GCP
13
GSA Capital Partners
United Kingdom
$800K +$36.8K +16,724 +4%
Two Sigma Investments
14
Two Sigma Investments
New York
$562K +$70.4K +31,939 +11%
Northern Trust
15
Northern Trust
Illinois
$522K +$135K +61,513 +26%
Susquehanna International Group
16
Susquehanna International Group
Pennsylvania
$437K +$440K +199,768 +390%
6CM
17
683 Capital Management
New York
$433K +$548K +248,790 New
State Street
18
State Street
Massachusetts
$430K +$135K +61,200 +33%
OAC
19
OMERS Administration Corp
Ontario, Canada
$388K +$491K +223,000 New
BCM
20
Bridgeway Capital Management
Texas
$301K +$381K +173,000 New
UBS Group
21
UBS Group
Switzerland
$297K -$270K -122,483 -42%
XT
22
XTX Topco
Cayman Islands
$291K -$95.9K -43,530 -21%
PAP
23
Persistent Asset Partners
Hong Kong
$247K +$313K +142,164 New
Jacobs Levy Equity Management
24
Jacobs Levy Equity Management
New Jersey
$228K +$249K +113,119 +640%
Qube Research & Technologies (QRT)
25
Qube Research & Technologies (QRT)
United Kingdom
$201K +$181K +81,974 +245%

INO Hedge Fund Activity: Q4 2025 in Review

102 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Inovio Pharmaceuticals (INO) for Q4 2025, worth a combined $57.5M — up 19% from $48.4M a quarter earlier.

Buyers outnumbered sellers: 21 funds opened new INO positions and 18 closed out — a net gain of 3 holders — while 25 added to existing stakes and 22 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $21.7M. The largest seller was Adage Capital Partners, cutting an estimated $1.93M.

  • 102 institutional investors held Inovio Pharmaceuticals (INO) as of Q4 2025, up from 99 in Q3 2025.
  • Funds reported $57.5M of Inovio Pharmaceuticals stock for Q4 2025, up 19% quarter-over-quarter.
  • 21 funds opened new Inovio Pharmaceuticals positions in Q4 2025 and 18 closed out, a net change of +3 holders.
  • The largest Inovio Pharmaceuticals buyer in Q4 2025 was Fidelity Investments, an estimated $21.7M added.
  • The largest Inovio Pharmaceuticals seller in Q4 2025 was Adage Capital Partners, an estimated $1.93M sold.

Based on aggregated 13F filings for Q4 2025.