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Inovio Pharmaceuticals
INO

102 hedge funds and large institutions have $57.5M invested in Inovio Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 21 funds opening new positions, 25 increasing their positions, 22 reducing their positions, and 18 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,161% more call options, than puts

Call options by funds: $2.02M | Put options by funds: $160K

19% more capital invested

Capital invested by funds: $48.4M → $57.5M (+$9.01M)

17% more first-time investments, than exits

New positions opened: 21 | Existing positions closed: 18

14% more repeat investments, than reductions

Existing positions increased: 25 | Existing positions reduced: 22

9.1% more ownership

Funds ownership: 38.97% → 48.07% (+9.1%)

3% more funds holding

Funds holding: 99 → 102 (+3)

Holders
102
Holders Change
+3
Holders Change %
+3.03%
% of All Funds
1.24%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
21
Increased
25
Reduced
22
Closed
18
Calls
$2.02M
Puts
$160K
Net Calls
+$1.86M
Net Calls Change
-$535K

Top Buyers

Rank Fund Capital Flow
1
Fidelity Investments
Fidelity Investments
Massachusetts
+$21.7M
2
ACM
ADAR1 Capital Management
Texas
+$3.27M
3
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$3.14M
4
Vanguard Group
Vanguard Group
Pennsylvania
+$1.33M
5
DP
Diadema Partners
New Jersey
+$1.18M

Top Sellers

Rank Fund Capital Flow
1
Adage Capital Partners
Adage Capital Partners
Massachusetts
-$1.93M
2
Morgan Stanley
Morgan Stanley
New York
-$1.5M
3
Bank of America
Bank of America
North Carolina
-$1.26M
4
Millennium Management
Millennium Management
New York
-$1.25M
5
Renaissance Technologies
Renaissance Technologies
New York
-$580K
Name Holding Trade Value Shares
Change 		Change in
Stake
SEIA
51
Signature Estate & Investment Advisors
California
$19.2K – – –
C
52
Covestor
United Kingdom
$10K – – –
SS
53
SBI Securities
Japan
$7.42K -$95 -43 -1%
Wells Fargo
54
Wells Fargo
California
$4.78K +$5.57K +2,528 +1,170%
Rockefeller Capital Management
55
Rockefeller Capital Management
New York
$3.54K – – –
SPIA
56
Steward Partners Investment Advisory
New York
$3.21K – – –
Royal Bank of Canada
57
Royal Bank of Canada
Ontario, Canada
$3K -$361K -163,791 -99%
Federated Hermes
58
Federated Hermes
Pennsylvania
$3K -$1.37K -623 -27%
AWM
59
Activest Wealth Management
Florida
$2.61K – – –
LWMI
60
Legacy Wealth Management (Idaho)
Idaho
$2.36K – – –
Osaic Holdings
61
Osaic Holdings
Arizona
$1.68K -$2.07K -941 -49%
PNC Financial Services Group
62
PNC Financial Services Group
Pennsylvania
$1.54K -$330 -150 -14%
MCM
63
MAI Capital Management
Ohio
$1.45K -$218 -99 -11%
Barclays
64
Barclays
United Kingdom
$1.26K +$1.59K +721 +72,100%
RhumbLine Advisers
65
RhumbLine Advisers
Massachusetts
$1.05K – – –
CA
66
Clearstead Advisors
Ohio
$870 – – –
NFSG
67
Newbridge Financial Services Group
Florida
$624 – – –
BNP Paribas Financial Markets
68
BNP Paribas Financial Markets
France
$612 -$23.4K -10,634 -97%
MAFA
69
MJT & Associates Financial Advisory
Minnesota
$566 – – –
PFO
70
Pioneer Family Office
Florida
$506 +$641 +291 New
Jones Financial Companies
71
Jones Financial Companies
Missouri
$418 -$13 -6 -2%
RFP
72
Root Financial Partners
California
$362 – – –
FDCDDQ
73
Federation des caisses Desjardins du Quebec
Quebec, Canada
$245 – – –
AAP
74
Arax Advisory Partners
Colorado
$179 – – –
National Bank of Canada
75
National Bank of Canada
Quebec, Canada
$172 +$128 +58 +141%
1 2
3
4 5

INO Hedge Fund Activity: Q4 2025 in Review

102 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Inovio Pharmaceuticals (INO) for Q4 2025, worth a combined $57.5M — up 19% from $48.4M a quarter earlier.

Buyers outnumbered sellers: 21 funds opened new INO positions and 18 closed out — a net gain of 3 holders — while 25 added to existing stakes and 22 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $21.7M. The largest seller was Adage Capital Partners, cutting an estimated $1.93M.

  • 102 institutional investors held Inovio Pharmaceuticals (INO) as of Q4 2025, up from 99 in Q3 2025.
  • Funds reported $57.5M of Inovio Pharmaceuticals stock for Q4 2025, up 19% quarter-over-quarter.
  • 21 funds opened new Inovio Pharmaceuticals positions in Q4 2025 and 18 closed out, a net change of +3 holders.
  • The largest Inovio Pharmaceuticals buyer in Q4 2025 was Fidelity Investments, an estimated $21.7M added.
  • The largest Inovio Pharmaceuticals seller in Q4 2025 was Adage Capital Partners, an estimated $1.93M sold.

Based on aggregated 13F filings for Q4 2025.