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Name Holding Trade Value Shares
Change
Change in
Stake
Goldman Sachs
26
Goldman Sachs
New York
$75M +$18.8M +252,870 +32%
BG
27
BlackRock Group
United Kingdom
$73.2M -$14.2M -190,863 -16%
Wells Fargo
28
Wells Fargo
California
$72M -$29.6M -397,654 -29%
American Century Companies
29
American Century Companies
Missouri
$70.8M -$18.8M -251,691 -20%
TCM
30
Tekla Capital Management
Massachusetts
$69.3M +$5.66M +76,000 +9%
Jennison Associates
31
Jennison Associates
New York
$68M -$81.7M -1,096,380 -54%
Canada Pension Plan Investment Board
32
Canada Pension Plan Investment Board
Ontario, Canada
$65.8M -$17.1M -229,200 -20%
Two Sigma Advisers
33
Two Sigma Advisers
New York
$65.5M +$3.87M +51,949 +6%
GGHC
34
Gilder Gagnon Howe & Co
New York
$63.2M -$6.77M -90,794 -9%
New York State Common Retirement Fund
35
New York State Common Retirement Fund
New York
$61.1M +$4.02M +53,922 +7%
Northern Trust
36
Northern Trust
Illinois
$61M +$3.24M +43,440 +6%
Federated Hermes
37
Federated Hermes
Pennsylvania
$52M +$1.62M +21,755 +3%
Bank of New York Mellon
38
Bank of New York Mellon
New York
$51.2M -$290K -3,891 -0.5%
Royal Bank of Canada
39
Royal Bank of Canada
Ontario, Canada
$45M +$25.2M +337,809 +119%
First Trust Advisors
40
First Trust Advisors
Illinois
$44M -$81.8M -1,097,860 -64%
AG
41
Artal Group
Luxembourg
$43.5M +$2.24M +30,000 +5%
Legal & General Group
42
Legal & General Group
United Kingdom
$43.4M -$739K -9,916 -2%
Bank of America
43
Bank of America
North Carolina
$43.3M -$16.5M -221,612 -27%
Two Sigma Investments
44
Two Sigma Investments
New York
$42M +$6.59M +88,422 +18%
TCIM
45
TIAA CREF Investment Management
New York
$40.7M -$27.1M -363,426 -39%
CS
46
Credit Suisse
Switzerland
$38.1M +$5.68M +76,153 +17%
CI
47
Capital International
California
$37.7M +$149K +2,000 +0.4%
Sumitomo Mitsui Trust Group
48
Sumitomo Mitsui Trust Group
Japan
$36.2M +$3.26M +43,784 +10%
FAM
49
Fred Alger Management
New York
$36.1M -$28.5M -382,670 -43%
Millennium Management
50
Millennium Management
New York
$35.7M +$15.9M +213,161 +76%