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Immuneering

86 hedge funds and large institutions have $209M invested in Immuneering in 2025 Q4 according to their latest regulatory filings, with 31 funds opening new positions, 27 increasing their positions, 12 reducing their positions, and 13 closing their positions.

New
Increased
Maintained
Reduced
Closed

183% more call options, than puts

Call options by funds: $2.34M | Put options by funds: $828K

138% more first-time investments, than exits

New positions opened: 31 | Existing positions closed: 13

125% more repeat investments, than reductions

Existing positions increased: 27 | Existing positions reduced: 12

50% more funds holding in top 10

Funds holding in top 10: 23 (+1)

26% more funds holding

Funds holding: 6886 (+18)

15% more capital invested

Capital invested by funds: $182M → $209M (+$26.6M)

13.48% less ownership

Funds ownership: 62.65%49.17% (-13%)

Holders
86
Holders Change
+18
Holders Change %
+26.47%
% of All Funds
1.05%
Holding in Top 10
3
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+50%
% of All Funds
0.04%
New
31
Increased
27
Reduced
12
Closed
13
Calls
$2.34M
Puts
$828K
Net Calls
+$1.52M
Net Calls Change
+$1.52M
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$63.7M +$5.77M +898,443 +10%
S
2
Sanofi
France
$17.8M
EAM
3
Empery Asset Management
New York
$17.6M +$17.2M +2,674,950 New
Vanguard Group
4
Vanguard Group
Pennsylvania
$16.9M +$983K +153,049 +6%
State Street
5
State Street
Massachusetts
$15.8M +$14.3M +2,229,374 +1,290%
T. Rowe Price Associates
6
T. Rowe Price Associates
Maryland
$13.1M +$1.25M +195,176 +11%
BlackRock
7
BlackRock
New York
$9.55M +$4.95M +770,521 +113%
Marshall Wace
8
Marshall Wace
United Kingdom
$4.68M +$2.83M +440,571 +162%
BOCH
9
Blue Owl Capital Holdings
New York
$4.38M +$738K +115,000 +21%
Geode Capital Management
10
Geode Capital Management
Massachusetts
$4.07M +$670K +104,409 +20%
OCM
11
Occam Crest Management
Connecticut
$3.28M
Morgan Stanley
12
Morgan Stanley
New York
$3.22M +$1.25M +194,760 +66%
Goldman Sachs
13
Goldman Sachs
New York
$2.1M +$2.05M +318,809 New
BGM
14
Burkehill Global Management
New York
$1.97M
SM
15
Southport Management
Wyoming
$1.83M +$32.1K +5,000 +2%
DC
16
Diametric Capital
Massachusetts
$1.62M -$34.3K -5,336 -2%
Barclays
17
Barclays
United Kingdom
$1.52M +$1.34M +208,608 +943%
DA
18
DCF Advisers
Connecticut
$1.41M +$1.38M +215,000 New
Bank of America
19
Bank of America
North Carolina
$1.41M +$1.1M +170,587 +390%
Two Sigma Investments
20
Two Sigma Investments
New York
$1.36M +$637K +99,284 +92%
UBS Group
21
UBS Group
Switzerland
$1.25M +$410K +63,931 +51%
Qube Research & Technologies (QRT)
22
Qube Research & Technologies (QRT)
United Kingdom
$1.09M +$1.06M +165,875 New
Renaissance Technologies
23
Renaissance Technologies
New York
$1M +$753K +117,300 +335%
6CM
24
683 Capital Management
New York
$992K +$968K +150,697 New
WP
25
Woodline Partners
California
$987K

IMRX Hedge Fund Activity: Q4 2025 in Review

86 of the 8,228 institutional investors tracked by Wall St. Rank reported a position in Immuneering (IMRX) for Q4 2025, worth a combined $209M — up 15% from $182M a quarter earlier.

Buyers outnumbered sellers: 31 funds opened new IMRX positions and 13 closed out — a net gain of 18 holders — while 27 added to existing stakes and 12 trimmed.

The largest buyer was State Street, adding an estimated $14.3M. The largest seller was ExodusPoint Capital Management, exiting entirely with an estimated $10.6M sold.

  • 86 institutional investors held Immuneering (IMRX) as of Q4 2025, up from 68 in Q3 2025.
  • Funds reported $209M of Immuneering stock for Q4 2025, up 15% quarter-over-quarter.
  • 31 funds opened new Immuneering positions in Q4 2025 and 13 closed out, a net change of +18 holders.
  • The largest Immuneering buyer in Q4 2025 was State Street, an estimated $14.3M added.
  • The largest Immuneering seller in Q4 2025 was ExodusPoint Capital Management, an estimated $10.6M sold.

Based on aggregated 13F filings for Q4 2025.